Search Results - "Galaup, Ariane"
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Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo
Published in Nature communications (20-11-2012)“…Endothelial adherens junctions maintain vascular integrity. Arteries and veins differ in their permeability but whether organization and strength of their…”
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2
Pharmacology of dimethanesulfonate alkylating agents: busulfan and treosulfan
Published in Expert opinion on drug metabolism & toxicology (01-03-2013)“…Among the dimethanesulfonates, busulfan, in combination with other alkylating agents or nucleoside analogues, is the cornerstone of high-dose chemotherapy. It…”
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3
Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis
Published in Nature Medicine (01-10-2011)“…Rapidly progressive glomerulonephritis (RPGN) is a form of severe kidney injury that can lead to promptly lethal renal failure. Pierre-Louis Tharaux and…”
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Enhanced angiogenesis and increased cardiac perfusion after myocardial infarction in protein tyrosine phosphatase 1B‐deficient mice
Published in The FASEB journal (01-08-2014)“…The protein tyrosine phosphatase 1B (PTP1B) modulates tyrosine kinase receptors, among which is the vascular endothelial growth factor receptor type 2…”
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Angiopoietin-Like 4 Prevents Metastasis through Inhibition of Vascular Permeability and Tumor Cell Motility and Invasiveness
Published in Proceedings of the National Academy of Sciences - PNAS (05-12-2006)“…Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hypoxia in both tumor and endothelial cells as well as in…”
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Alteration of Developmental and Pathological Retinal Angiogenesis in angptl4-deficient Mice
Published in The Journal of biological chemistry (21-10-2011)“…Proper vessel maturation, remodeling of endothelial junctions, and recruitment of perivascular cells is crucial for establishing and maintaining vessel…”
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Extracellular Matrix–Bound Angiopoietin-Like 4 Inhibits Endothelial Cell Adhesion, Migration, and Sprouting and Alters Actin Cytoskeleton
Published in Circulation research (24-11-2006)“…Angiopoietin-like 4 (ANGPTL4) is a secreted protein that belongs to the angiopoietin family and is involved in angiogenesis and metabolism regulation. We…”
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Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease
Published in The Journal of clinical investigation (01-05-2008)“…Patients with sickle-cell disease (SCD) suffer from tissue damage and life-threatening complications caused by vasoocclusive crisis (VOC). Endothelin receptors…”
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Protection Against Myocardial Infarction and No-Reflow Through Preservation of Vascular Integrity by Angiopoietin-Like 4
Published in Circulation (New York, N.Y.) (03-01-2012)“…Increased permeability, predominantly controlled by endothelial junction stability, is an early event in the deterioration of vascular integrity in ischemic…”
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ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2
Published in The Journal of pathology (01-12-2016)“…Dynamic control of endothelial cell junctions is essential for vascular homeostasis and angiogenesis. We recently provided genetic evidence that ANGPTL4 is a…”
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11
Platform trials
Published in Therapie (01-01-2023)“…For the past few years, platform trials have experienced a significant increase, recently amplified by the COVID-19 pandemic. The implementation of a platform…”
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12
Canstatin acts on endothelial and tumor cells via mitochondrial damage initiated through interaction with αvβ3 and αvβ5 integrins
Published in Cancer research (Chicago, Ill.) (15-05-2005)“…Abstract Canstatin, the noncollagenous domain of collagen type IV α-chains, belongs to a series of collagen-derived angiogenic inhibitors. We have elucidated…”
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Attractiveness of France for international clinical research: 8th survey conducted by Leem (French association for pharmaceutical companies)
Published in Therapie (01-10-2018)“…The Leem (French association of pharmaceutical companies) has conducted the eighth survey on attractiveness of France for clinical research. It serves to…”
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How the new European data protection regulation affects clinical research and recommendations?
Published in Therapie (01-02-2019)“…Clinical research on human subjects or their data is confronted with conflicting requirements with, on one hand, the principle of open science (transparency…”
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ANGPTL4-[alpha]v[beta]3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2
Published in The Journal of pathology (01-12-2016)“…Dynamic control of endothelial cell junctions is essential for vascular homeostasis and angiogenesis. We recently provided genetic evidence that ANGPTL4 is a…”
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16
ANGPTL4- alpha v beta 3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2
Published in The Journal of pathology (01-12-2016)“…Dynamic control of endothelial cell junctions is essential for vascular homeostasis and angiogenesis. We recently provided genetic evidence that ANGPTL4 is a…”
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17
Radiation and inhibition of angiogenesis by canstatin synergize to induce HIF-1α–mediated tumor apoptotic switch
Published in The Journal of clinical investigation (01-07-2007)“…Tumor radioresponsiveness depends on endothelial cell death, which leads in turn to tumor hypoxia. Radiation-induced hypoxia was recently shown to trigger…”
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ANGPTL4 modulates in vivo developmental and pathological angiogenesis
Published in Vascular pharmacology (01-05-2012)Get full text
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Protecting vascular integrity in acute myocardial ischemia-reperfusion
Published in M.S. Médecine sciences (01-02-2012)Get more information
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20
Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis
Published in Nature medicine (01-11-2011)Get full text
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