Low-renin hypertension. Occurrence in vascular complications

Two hundred one patients with essential hypertension, who had studies of their renin-aldosterone system performed between April 1967 and December 1972, were surveyed for myocardial infraction or cerebrovascular accident. Of the patients, 42% had low plasma renin activity. Myocardial infractions or c...

Full description

Saved in:

Bibliographic Details
Published in:	Archives of internal medicine (1960) Vol. 135; no. 2; p. 260
Main Authors:	Galati, S C, Channick, B J, Biddle, C M, Marks, A D
Format:	Journal Article
Language:	English
Published:	United States 01-02-1975
Subjects:	Black or African American Black People Cerebrovascular Disorders - epidemiology Cerebrovascular Disorders - etiology Humans Hypertension - blood Hypertension - complications Myocardial Infarction - epidemiology Myocardial Infarction - etiology Pennsylvania Renin - blood Retrospective Studies White People Pennsylvania
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Two hundred one patients with essential hypertension, who had studies of their renin-aldosterone system performed between April 1967 and December 1972, were surveyed for myocardial infraction or cerebrovascular accident. Of the patients, 42% had low plasma renin activity. Myocardial infractions or cerebrovascular accidents were documented in 15% of those with low plasms renin activity and in 5% of those with normal plasma renin activity. When adjustments were made for differences in afe and blood pressure , a protective effect in low-renin hypertension was evident. When black patients were considered separately,there was no difference in diastolic blood pressure; however, vascular complications were not less frequent in low-renin hypertensives. The results suggest that low plasma renin activity does not protect against the development of vascular complications in essential hypertension.
ISSN:	0003-9926
DOI:	10.1001/archinte.1975.00330020064008