Search Results - "Galal, Alaaeldin M. F"

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  1. 1

    Synthesis and biological evaluation of novel 5-chloro-N-(4-sulfamoylbenzyl) salicylamide derivatives as tubulin polymerization inhibitors by Galal, Alaaeldin M. F, Soltan, Maha M, Ahmed, Esam R, Hanna, Atef G

    Published in MedChemComm (2018)
    “…A novel series of sulfonamide derivatives, coupled with a salicylamide scaffold, was designed and synthesized. The structures of the synthesized compounds were…”
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    Journal Article
  2. 2
  3. 3

    Configuration and molecular structure of 5-chloro-N-(4-sulfamoylbenzyl) salicylamide derivatives by Galal, Alaaeldin M.F., Atta, Diaa, Abouelsayed, Ahmed, Ibrahim, Medhat A., Hanna, Atef G.

    “…A systematic study on sulfonamide derivatives with salicylamide core is presented for possible use in pharmaceutical applications. The molecular structure of…”
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    Journal Article
  4. 4

    Development, synthesis, and biological evaluation of sulfonyl‐α‐l‐amino acids as potential anti‐Helicobacter pylori and IMPDH inhibitors by Galal, Alaaeldin M. F., Mohamed, Hanaa S., Abdel‐Aziz, Marwa M., Hanna, Atef G.

    Published in Archiv der Pharmazie (Weinheim) (01-06-2021)
    “…Inosine 5ʹ‐monophosphate dehydrogenase (IMPDH) catalyzes a crucial step in the biosynthesis of DNA and RNA, and it has been exploited as a promising target for…”
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    Journal Article
  5. 5

    Structure and absolute configuration of some 5-chloro-2-methoxy-N-phenylbenzamide derivatives by Galal, Alaaeldin M F, Shalaby, Elsayed M., Abouelsayed, Ahmed, Ibrahim, Medhat A., Al-Ashkar, Emad, Hanna, Atef G

    “…The absolute configuration of 5-chloro-2-methoxy-N-phenylbenzamide single crystal [compound (1)] and the effect of introducing –[CH2]n–, n=1,2 group adjacent…”
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    Journal Article
  6. 6

    Cytotoxicity of multicellular cancer spheroids, antibacterial, and antifungal of selected sulfonamide derivatives coupled with a salicylamide and/or anisamide scaffold by Galal, Alaaeldin M. F., Fayad, Walid, Mettwally, Walaa S. A., Gomaa, Sanaa K., Ahmed, Esam R., El-Refai, Heba A., Hanna, Atef G.

    Published in Medicinal chemistry research (01-09-2019)
    “…In an attempt to overcome the drawbacks of the cancer monolayers model (2D), the 3-dimensional (3D) multicellular cancer spheroids (MCS) have been developed…”
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    Journal Article