Search Results - "Galal, Alaaeldin M. F"
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Synthesis and biological evaluation of novel 5-chloro-N-(4-sulfamoylbenzyl) salicylamide derivatives as tubulin polymerization inhibitors
Published in MedChemComm (2018)“…A novel series of sulfonamide derivatives, coupled with a salicylamide scaffold, was designed and synthesized. The structures of the synthesized compounds were…”
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Phytochemical and antimicrobial investigation of the leaves of five Egyptian mango cultivars and evaluation of their essential oils as preservatives materials
Published in Journal of food science and technology (01-08-2021)“…The sterols, hydrocarbons and fatty acids constituents of the leaves of five mango cultivars locally implanted in Egypt were identified. The effect of their…”
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Configuration and molecular structure of 5-chloro-N-(4-sulfamoylbenzyl) salicylamide derivatives
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-05-2019)“…A systematic study on sulfonamide derivatives with salicylamide core is presented for possible use in pharmaceutical applications. The molecular structure of…”
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Development, synthesis, and biological evaluation of sulfonyl‐α‐l‐amino acids as potential anti‐Helicobacter pylori and IMPDH inhibitors
Published in Archiv der Pharmazie (Weinheim) (01-06-2021)“…Inosine 5ʹ‐monophosphate dehydrogenase (IMPDH) catalyzes a crucial step in the biosynthesis of DNA and RNA, and it has been exploited as a promising target for…”
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Structure and absolute configuration of some 5-chloro-2-methoxy-N-phenylbenzamide derivatives
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-01-2018)“…The absolute configuration of 5-chloro-2-methoxy-N-phenylbenzamide single crystal [compound (1)] and the effect of introducing –[CH2]n–, n=1,2 group adjacent…”
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Cytotoxicity of multicellular cancer spheroids, antibacterial, and antifungal of selected sulfonamide derivatives coupled with a salicylamide and/or anisamide scaffold
Published in Medicinal chemistry research (01-09-2019)“…In an attempt to overcome the drawbacks of the cancer monolayers model (2D), the 3-dimensional (3D) multicellular cancer spheroids (MCS) have been developed…”
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