Search Results - "Galactéros, Frederic"

Eculizumab salvage therapy for delayed hemolysis transfusion reaction in sickle cell disease patients by Dumas, Guillaume, Habibi, Anoosha, Onimus, Thierry, Merle, Jean-Claude, Razazi, Keyvan, Mekontso Dessap, Armand, Galactéros, Frederic, Michel, Marc, Frémeaux Bacchi, Veronique, Noizat Pirenne, France, Bartolucci, Pablo

Get full text

Safety and Efficacy of Mitapivat in Pyruvate Kinase Deficiency by Grace, Rachael F, Rose, Christian, Layton, D. Mark, Galactéros, Frédéric, Barcellini, Wilma, Morton, D. Holmes, van Beers, Eduard J, Yaish, Hassan, Ravindranath, Yaddanapudi, Kuo, Kevin H.M, Sheth, Sujit, Kwiatkowski, Janet L, Barbier, Ann J, Bodie, Susan, Silver, Bruce, Hua, Lei, Kung, Charles, Hawkins, Peter, Jouvin, Marie-Hélène, Bowden, Chris, Glader, Bertil

“…In this study, approximately half the patients with red-cell pyruvate kinase deficiency who were treated with mitapivat had an improvement in their hemoglobin…”
Get full text

Incidence and predictive score for delayed hemolytic transfusion reaction in adult patients with sickle cell disease by Narbey, David, Habibi, Anoosha, Chadebech, Philippe, Mekontso‐Dessap, Armand, Khellaf, Mehdi, Lelièvre, Jean‐Daniel, Godeau, Bertrand, Michel, Marc, Galactéros, Frédéric, Djoudi, Rachid, Bartolucci, Pablo, Pirenne, France

“…Delayed hemolytic transfusion reaction (DHTR) is a life‐threatening complication of transfusion in sickle cell disease (SCD). The frequency of DHTR is…”
Get full text

Complement activation in sickle cell disease: Dependence on cell density, hemolysis and modulation by hydroxyurea therapy by Roumenina, Lubka T., Chadebech, Philippe, Bodivit, Gwellaouen, Vieira‐Martins, Paula, Grunenwald, Anne, Boudhabhay, Idris, Poillerat, Victoria, Pakdaman, Sadaf, Kiger, Laurent, Jouard, Alicia, Audureau, Etienne, Pirenne, France, Galactéros, Frédéric, Frémeaux‐Bacchi, Véronique, Bartolucci, Pablo

“…The complement system is an innate immune defense cascade that can cause tissue damage when inappropriately activated. Evidence for complement over activation…”
Get full text

Epidemiology and disease burden of sickle cell disease in France: A descriptive study based on a French nationwide claim database by Leleu, Henri, Arlet, Jean Benoit, Habibi, Anoosha, Etienne-Julan, Maryse, Khellaf, Mehdi, Adjibi, Yolande, Pirenne, France, Pitel, Marine, Granghaud, Anna, Sinniah, Cynthia, De Montalembert, Mariane, Galacteros, Frédéric

“…Context Sickle cell disease (SCD) is a severe hematological disorder. The most common acute complication of SCD is vaso-occlusive crisis (VOC), but SCD is a…”
Get full text

Clinical and biological features in PIEZO1 -hereditary xerocytosis and Gardos channelopathy: a retrospective series of 126 patients by Picard, Véronique, Guitton, Corinne, Thuret, Isabelle, Rose, Christian, Bendelac, Laurence, Ghazal, Kaldoun, Aguilar-Martinez, Patricia, Badens, Catherine, Barro, Claire, Bénéteau, Claire, Berger, Claire, Cathébras, Pascal, Deconinck, Eric, Delaunay, Jacques, Durand, Jean-Marc, Firah, Nadia, Galactéros, Frédéric, Godeau, Bertrand, Jaïs, Xavier, de Jaureguiberry, Jean-Pierre, Le Stradic, Camille, Lifermann, François, Maffre, Robert, Morin, Gilles, Perrin, Julien, Proulle, Valérie, Ruivard, Marc, Toutain, Fabienne, Lahary, Agnès, Garçon, Loïc

“…We describe the clinical, hematologic and genetic characteristics of a retrospective series of 126 subjects from 64 families with hereditary xerocytosis…”
Get full text

Clinical management of adult sickle-cell disease by Bartolucci, Pablo, Galactéros, Frédéric

“…PURPOSE OF REVIEWThis review provides an overview of the clinical management of sickle-cell disease (SCD) with recently published findings. RECENT…”
Get full text

Sotatercept, a novel transforming growth factor β ligand trap, improves anemia in β-thalassemia: a phase II, open-label, dose-finding study by Cappellini, Maria Domenica, Porter, John, Origa, Raffaella, Forni, Gian Luca, Voskaridou, Ersi, Galactéros, Frédéric, Taher, Ali T, Arlet, Jean-Benoît, Ribeil, Jean-Antoine, Garbowski, Maciej, Graziadei, Giovanna, Brouzes, Chantal, Semeraro, Michaela, Laadem, Abderrahmane, Miteva, Dimana, Zou, Jun, Sung, Victoria, Zinger, Tatiana, Attie, Kenneth M, Hermine, Olivier

“…β-thalassemia, a hereditary blood disorder caused by defective synthesis of hemoglobin β globin chains, leads to ineffective erythropoiesis and chronic anemia…”
Get full text

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci by Canver, Matthew C, Lessard, Samuel, Pinello, Luca, Wu, Yuxuan, Ilboudo, Yann, Stern, Emily N, Needleman, Austen J, Galactéros, Frédéric, Brugnara, Carlo, Kutlar, Abdullah, McKenzie, Colin, Reid, Marvin, Chen, Diane D, Das, Partha Pratim, A Cole, Mitchel, Zeng, Jing, Kurita, Ryo, Nakamura, Yukio, Yuan, Guo-Cheng, Lettre, Guillaume, Bauer, Daniel E, Orkin, Stuart H

“…Stuart Orkin, Daniel Bauer and colleagues present DNA Striker , a computational tool to design variant-aware saturating-mutagenesis screens with multiple…”
Get full text

Mitapivat versus Placebo for Pyruvate Kinase Deficiency by Al-Samkari, Hanny, Galactéros, Frédéric, Glenthøj, Andreas, Rothman, Jennifer A, Andres, Oliver, Grace, Rachael F, Morado-Arias, Marta, Layton, D. Mark, Onodera, Koichi, Verhovsek, Madeleine, Barcellini, Wilma, Chonat, Satheesh, Judge, Malia P, Zagadailov, Erin, Xu, Rengyi, Hawkins, Peter, Beynon, Vanessa, Gheuens, Sarah, van Beers, Eduard J

“…Pyruvate kinase deficiency, the most common genetic lesion in the glycolytic pathway, leads to chronic hemolytic anemia. Mitapivat, an oral agent, can activate…”
Get full text

Clinical phenotypes and outcomes of precapillary pulmonary hypertension of sickle cell disease by Savale, Laurent, Habibi, Anoosha, Lionnet, François, Maitre, Bernard, Cottin, Vincent, Jais, Xavier, Chaouat, Ari, Artaud-Macari, Elise, Canuet, Matthieu, Prevot, Grégoire, Chantalat-Auger, Christelle, Montani, David, Sitbon, Olivier, Galacteros, Fréderic, Simonneau, Gérald, Parent, Florence, Bartolucci, Pablo, Humbert, Marc

“…Precapillary pulmonary hypertension (PH) is a devastating complication of sickle cell disease (SCD). Little is known about the influence of the SCD genotype on…”
Get full text

Whole‐blood CCR7 expression and chemoattraction in red blood cell alloimmunization by Tamagne, Marie, Pakdaman, Sadaf, Bartolucci, Pablo, Habibi, Anoosha, Galactéros, Frédéric, Pirenne, France, Vingert, Benoît

Get full text

Real‐Life experience with hydroxyurea in patients with sickle cell disease: Results from the prospective ESCORT‐HU cohort study by Montalembert, Mariane, Voskaridou, Ersi, Oevermann, Lena, Cannas, Giovanna, Habibi, Anoosha, Loko, Gylna, Joseph, Laure, Colombatti, Raffaella, Bartolucci, Pablo, Brousse, Valentine, Galactéros, Frédéric

“…Several controlled studies have evidenced good efficacy and short‐term and mid‐term safety profiles for hydroxyurea (HU), which has become the cornerstone for…”
Get full text

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia by Cavazzana-Calvo, Marina, Payen, Emmanuel, Negre, Olivier, Wang, Gary, Hehir, Kathleen, Fusil, Floriane, Down, Julian, Denaro, Maria, Brady, Troy, Westerman, Karen, Cavallesco, Resy, Gillet-Legrand, Beatrix, Caccavelli, Laure, Sgarra, Riccardo, Maouche-Chrétien, Leila, Bernaudin, Françoise, Girot, Robert, Dorazio, Ronald, Mulder, Geert-Jan, Polack, Axel, Bank, Arthur, Soulier, Jean, Larghero, Jérôme, Kabbara, Nabil, Dalle, Bruno, Gourmel, Bernard, Socie, Gérard, Chrétien, Stany, Cartier, Nathalie, Aubourg, Patrick, Fischer, Alain, Cornetta, Kenneth, Galacteros, Frédéric, Beuzard, Yves, Gluckman, Eliane, Bushman, Frederick, Hacein-Bey-Abina, Salima, Leboulch, Philippe

“…Gene therapy success Blood disorders caused by abnormal β-globin — β-thalassaemia and sickle cell disease — are the most prevalent inherited disorders…”
Get full text

How to implement endurance exercise training in sickle cell disease by Messonnier, Laurent A, Riccetti, Manon, Chatel, Benjamin, Galactéros, Frédéric, Gellen, Barnabas, Rupp, Thomas, Féasson, Léonard, Bartolucci, Pablo

Get full text

A Hemodynamic Study of Pulmonary Hypertension in Sickle Cell Disease by Parent, Florence, Bachir, Dora, Inamo, Jocelyn, Lionnet, François, Driss, Françoise, Loko, Gylna, Habibi, Anoosha, Bennani, Soumiya, Savale, Laurent, Adnot, Serge, Maitre, Bernard, Yaïci, Azzedine, Hajji, Leila, O'Callaghan, Dermot S, Clerson, Pierre, Girot, Robert, Galacteros, Frederic, Simonneau, Gerald

“…Patients with sickle cell disease underwent ECG with assessment of tricuspid valve regurgitant jet velocity (TRJV) to screen for pulmonary hypertension,…”
Get full text

A rare G6PD variant (c.383T > G; p.128Leu > Arg) with a molecular pathophysiological mechanism similar to that of G6PD A − (68Val > Met, 126Asn > Asp) by Moradkhani, Kamran, Bahuau, Michel, Préhu, Claude, Martin, Natacha, Bimet, Catherine, Galactéros, Frederic, Wajcman, Henri

“…We report the second documented observation of a rare class-III variant, we named G6PD Pyrgos, [c.383 T > G, p.128Leu > Arg] found in a Greek family. A…”
Get full text

Fetal Hemoglobin Decrease During Voxelotor Treatment by De Luna, Gonzalo, Habibi, Anoosha, Moutereau, Stéphane, Martino, Suella, Alhamrouni, Jamila, Morel, Celia, Pelinski, Yanis, Zaouali, Yosr, Galactéros, Frédéric, Bartolucci, Pablo

“…Voxelotor modifies hemoglobin-oxygen affinity improving anemia and reducing hemolysis in sickle cell patients. However, the impact of Voxelotor on fetal…”
Get full text

Determination of hydroxyurea in human plasma by HPLC-UV using derivatization with xanthydrol by Legrand, Tiphaine, Rakotoson, Marie-Georgine, Galactéros, Frédéric, Bartolucci, Pablo, Hulin, Anne

“…[Display omitted] •Hydroxyurea is a challenging compound for chromatographic separation and detection.•A simple method for hydroxyurea determination in plasma…”
Get full text

Cardiac diastolic maladaptation is associated with the severity of exercise intolerance in sickle cell anemia patients by d’Humières, Thomas, Bouvarel, Antoine, Boyer, Laurent, Savale, Laurent, Guillet, Henri, Alassaad, Lara, de Luna, Gonzalo, Berti, Enora, Iles, Sihem, Pham Hung d’Alexandry d’Orengiani, Anne Laure, Audureau, Etienne, Troupe, Marie-Joelle, Schlatter, Reine-Claude, Lamadieu, Anaïs, Galactéros, Frédéric, Derumeaux, Geneviève, Messonnier, Laurent A., Bartolucci, Pablo

“…This pilot study focusing on Sickle Cell Anemia (SCA) patients offers a comprehensive and integrative evaluation of respiratory, cardiovascular, hemodynamic,…”
Get full text