Search Results - "Gakiopoulou, Hariklia"

Histone Deacetylase (HDAC) Inhibitors: A Promising Weapon to Tackle Therapy Resistance in Melanoma by Palamaris, Kostas, Moutafi, Myrto, Gakiopoulou, Hariklia, Theocharis, Stamatios

“…Melanoma is an aggressive malignant tumor, arising more commonly on the skin, while it can also occur on mucosal surfaces and the uveal tract of the eye. In…”
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Podocyte-targeted Heme Oxygenase (HO)-1 overexpression exacerbates age-related pathology in the rat kidney by Poulaki, Elpida, Detsika, Maria G., Fourtziala, Eythimia, Lianos, Elias A., Gakiopoulou, Hariklia

“…Although Heme Oxygenase-1 (HO-1) induction in various forms of kidney injury is protective, its role in age-related renal pathology is unknown. In the ageing…”
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Targeted proteomic analysis dataset of archival core human kidney biopsies to investigate the biology of hypertensive nephropathy by Barkas, Georgios, Makridakis, Manousos, Gakiopoulou, Hariklia, Vlahakos, Demetrios

“…Hypertensive nephropathy is the second most frequent cause of end-stage renal disease in western societies. In previous experiments in our laboratory with…”
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NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE by Georgakis, Spiros, Gkirtzimanaki, Katerina, Papadaki, Garyfalia, Gakiopoulou, Hariklia, Drakos, Elias, Eloranta, Maija-Leena, Makridakis, Manousos, Kontostathi, Georgia, Zoidakis, Jerome, Baira, Eirini, Rönnblom, Lars, Boumpas, Dimitrios T, Sidiropoulos, Prodromos, Verginis, Panayotis, Bertsias, George

“…IL-33, a nuclear alarmin released during cell death, exerts context-specific effects on adaptive and innate immune cells, eliciting potent inflammatory…”
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The P274S Mutation of Lecithin-Cholesterol Acyltransferase (LCAT) and Its Clinical Manifestations in a Large Kindred by Fountoulakis, Nikolaos, Lioudaki, Eirini, Lygerou, Dimitra, Dermitzaki, Eleftheria-Kleio, Papakitsou, Ioanna, Kounali, Vasiliki, Holleboom, Adriaan G., Stratigis, Spyros, Belogianni, Christina, Syngelaki, Paraskevi, Stratakis, Stavros, Evangeliou, Athanasios, Gakiopoulou, Hariklia, Kuivenhoven, Jan Albert, Wevers, Ron, Dafnis, Eugene, Stylianou, Kostas

“…Lecithin-cholesterol acyltransferase (LCAT) catalyzes the maturation of high-density lipoprotein. Homozygosity for loss-of-function mutations causes familial…”
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Clinical impact of repeat renal biopsies in patients with lupus nephritis: Renal biopsy is essential especially later in the course of the disease by Marinaki, Smaragdi, Kapsia, Eleni, Liapis, George, Gakiopoulou, Hariklia, Skalioti, Chrysanthi, Kolovou, Kyriaki, Boletis, John

“…The clinical impact of repeat renal biopsies in patients with lupus nephritis (LN) is still debatable. The aim of this retrospective analysis was to assess…”
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Increase of HO-1 Expression in Critically Ill COVID-19 Patients Is Associated with Poor Prognosis and Outcome by Detsika, Maria G., Nikitopoulou, Ioanna, Veroutis, Dimitris, Vassiliou, Alice G., Jahaj, Edison, Tsipilis, Stamatis, Athanassiou, Nikolaos, Gakiopoulou, Hariklia, Gorgoulis, Vassilis G., Dimopoulou, Ioanna, Orfanos, Stylianos E., Kotanidou, Anastasia

“…Heme-oxygenase (HO)-1 is a cytoprotective enzyme with strong antioxidant and anti-apoptotic properties and previous reports have also emphasized the antiviral…”
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Validation of the International IgA Nephropathy Prediction Tool in the Greek Registry of IgA Nephropathy by Papasotiriou, Marios, Stangou, Maria, Chlorogiannis, Dimitris, Marinaki, Smaragdi, Xydakis, Dimitrios, Sampani, Erasmia, Lioulios, Georgios, Kapsia, Eleni, Zerbala, Synodi, Koukoulaki, Maria, Moustakas, Georgios, Fokas, Stavros, Dounousi, Evangelia, Duni, Anila, Papadaki, Antonia, Damianakis, Nikolaos, Bacharaki, Dimitra, Stylianou, Kostas, Gakiopoulou, Hariklia, Liapis, George, Sakellaropoulos, Georgios, Papachristou, Evangelos, Boletis, Ioannis, Papagianni, Aikaterini, Goumenos, Dimitrios S

“…Immunoglobulin A nephropathy (IgAN) is among the commonest glomerulonephritides in Greece and an important cause of end-stage kidney disease (ESKD) with an…”
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Membranoproliferative glomerulonephritis in a patient with chronic brucellosis by Provatopoulou, Simella, Papasotiriou, Marios, Papachristou, Evangelos, Gakiopoulou, Hariklia, Marangos, Markos, Goumenos, Dimitrios S

“…Brucellosis is the most common zoonotic disease in Greece, with an endemic distribution and can affect any organ. Infiltration of the renal parenchyma causes…”
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The complement interference phenomenon as a cause of underestimation of high titer anti-HLA antibodies in a renal transplant recipient by Vittoraki, Angeliki G, Stylianou, Kostas G, Skoumi, Dimitra A, Ioannou, Sofia I, Vrani, Vasiliki P, Gakiopoulou, Hariklia H, Daphnis, Eugene K, Iniotaki, Aliki G

“…Single antigen bead assay is the most sensitive laboratory tool for the anti-HLA antibody (Ab) identification in renal transplant recipients. However, this…”
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PLA2R-Negative Membranous Nephropathy Presenting as a Prodrome of IgG4-Related Autoimmune Pancreatitis by Velegraki, Magdalini, Stylianou, Kostas G., Xydakis, Dimitrios, Gakiopoulou, Hariklia, Voudoukis, Evangelos, Lygerou, Dimitra, Dermitzaki, Eleftheria-Kleio, Mpitouli, Aphrodite, Paspatis, Gregorios, Theodoropoulou, Angeliki

“…Membranous nephropathy (MN) with tubulointerstitial nephritis (TIN) is an established manifestation of immunoglobulin G4 (IgG4)-related disease (IgG4-RD). A…”
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Immunohistochemical evaluation of podocalyxin expression in glomerulopathies associated with nephrotic syndrome by Kavoura, Evangelia, MD, Gakiopoulou, Hariklia, MD, PhD, Paraskevakou, Helen, MD, PhD, Marinaki, Smaragdi, MD, Agrogiannis, George, MD, Stofas, Anastasios, MD, Boletis, Ioannis, MD, Patsouris, Efstratios, MD, PhD, Lazaris, Andreas C., MD, PhD

“…Summary It is now well established that morphological change of podocytes is closely correlated to the development of proteinuria. The aim of this study was to…”
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Repair of gastric defects with an equine pericardial patch by Spiliopoulos, Kostantinos, Markakis, Charalampos, Tomos, Periklis, Gakiopoulou, Hariklia, Nikolopoulos, Ioannis, Spartalis, Eleftherios, Kontzoglou, Kostantinos, Safioleas, Michael

“…Purposes The objective of this study was to test the efficacy of an equine pericardial patch for repairing full-thickness defects of the stomach wall. Methods…”
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Replication protein A: a reliable biologic marker of prognostic and therapeutic value in human astrocytic tumors by Kanakis, Dimitrios, MD, PhD, Levidou, Georgia, MD, MSc, PhD, Gakiopoulou, Hariklia, MD, PhD, Eftichiadis, Christos, MD, Thymara, Irene, MD, PhD, Fragkou, Paraskevi, MD, Trigka, Eleni-Andriana, MD, Boviatsis, Efstathios, MD, PhD, Patsouris, Efstratios, MD, PhD, Korkolopoulou, Penelope, MD, PhD

“…Summary Replication protein A is a single-stranded DNA–binding protein that is required for the stabilization of single-stranded DNA and identified in…”
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Acute Interstitial Nephritis and Membranous Nephropathy in the Context of IgG4-Related Disease by Stylianou, Kostas, Maragkaki, Eleftheria, Tzanakakis, Michael, Stratakis, Stavros, Gakiopoulou, Hariklia, Daphnis, Eugene

“…We present the case of a patient with IgG4-related disease, which manifested in an asynchronous manner as vitiligo, cholecystitis, sialadenitis,…”
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Possible association of CEA expression with oxyphilic change but not with C-cell hyperplasia in Hashimoto’s thyroiditis by Gakiopoulou, Hariklia, Litsiou, Eleni, Valaris, Konstantinos, Balafoutas, Dimitrios, Patsouris, Efstratios, Tseleni-Balafouta, Sofia

“…Reactive C-cell hyperplasia (CCH) has been observed in cases of autoimmune Hashimoto’s thyroiditis; however, its occurrence in Graves’ disease, the other major…”
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Tissue Inhibitor of Metalloproteinase-2 as a Multifunctional Molecule of Which the Expression Is Associated with Adverse Prognosis of Patients with Urothelial Bladder Carcinomas by GAKIOPOULOU, Hariklia, NAKOPOULOU, Lydia, SIATELIS, Argyris, MAVROMMATIS, Ioannis, PANAYOTOPOULOU, Effie G, TSIRMPA, Ioanna, STRAVODIMOS, Constantinos, GIANNOPOULOS, Aris

“…Purpose: Tissue inhibitors of metalloproteinases (TIMPs) regulate matrix metalloproteinase (MMP) activity controlling the breakdown of extracellular matrix…”
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REDD1/autophagy pathway promotes thromboinflammation and fibrosis in human systemic lupus erythematosus (SLE) through NETs decorated with tissue factor (TF) and interleukin-17A (IL-17A) by Frangou, Eleni, Chrysanthopoulou, Akrivi, Mitsios, Alexandros, Kambas, Konstantinos, Arelaki, Stella, Angelidou, Iliana, Arampatzioglou, Athanasios, Gakiopoulou, Hariklia, Bertsias, George K, Verginis, Panayotis, Ritis, Konstantinos, Boumpas, Dimitrios T

“…The release of neutrophil extracellular traps (NETs) represents a novel neutrophil effector function in systemic lupus erythematosus (SLE) pathogenesis…”
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Nuclear hTERT Immunohistochemical Expression is Associated with Survival of Patients with Urothelial Bladder Cancer by MAVROMMATIS, John, MYLONA, Eleni, GAKIOPOULOU, Hariklia, STRAVODIMOS, Constantinos, ZERVAS, Anastasios, GIANNOPOULOS, Aris, NAKOPOULOU, Lydia

“…Background: The role of telomere in tumorigenesis is complex. While telomerase activation is suggested to be necessary for tumor growth, it may also help in…”
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Undifferentiated giant cell type carcinoma of the gallbladder with sarcomatoid dedifferentiation: a case report and review of the literature by Manouras, Andreas, Genetzakis, Michael, Lagoudianakis, Emmanuel E, Markogiannakis, Haridimos, Papadima, Artemisia, Agrogiannis, George, Gakiopoulou, Hariklia, Kekis, Panagiotis, Filis, Konstantinos, Patsouris, Efstratios

“…Abstract Introduction Undifferentiated gallbladder carcinoma is a rare entity. Among unusual types of undifferentiated gallbladder carcinoma, giant cell type…”
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