Search Results - "Gaipa, Giuseppe"

Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse by Good, Zinaida, Sarno, Jolanda, Jager, Astraea, Samusik, Nikolay, Aghaeepour, Nima, Simonds, Erin F, White, Leah, Lacayo, Norman J, Fantl, Wendy J, Fazio, Grazia, Gaipa, Giuseppe, Biondi, Andrea, Tibshirani, Robert, Bendall, Sean C, Nolan, Garry P, Davis, Kara L

“…Mass cytometry of diagnostic biopsies from children with B cell precursor acute lymphoblastic leukemia identifies a signaling state that predicts relapse…”
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Recurrent SETBP1 mutations in atypical chronic myeloid leukemia by Piazza, Rocco, Valletta, Simona, Winkelmann, Nils, Redaelli, Sara, Spinelli, Roberta, Pirola, Alessandra, Antolini, Laura, Mologni, Luca, Donadoni, Carla, Papaemmanuil, Elli, Schnittger, Susanne, Kim, Dong-Wook, Boultwood, Jacqueline, Rossi, Fabio, Gaipa, Giuseppe, De Martini, Greta P, di Celle, Paola Francia, Jang, Hyun Gyung, Fantin, Valeria, Bignell, Graham R, Magistroni, Vera, Haferlach, Torsten, Pogliani, Enrico Maria, Campbell, Peter J, Chase, Andrew J, Tapper, William J, Cross, Nicholas C P, Gambacorti-Passerini, Carlo

“…Carlo Gambacorti-Passerini and colleagues identify recurrent SETBP1 mutations in atypical chronic myeloid leukemia. The mutations, which cluster in a small…”
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Risk of Relapse of Childhood Acute Lymphoblastic Leukemia Is Predicted By Flow Cytometric Measurement of Residual Disease on Day 15 Bone Marrow by BASSO, Giuseppe, VELTRONI, Marinella, CONTER, Valentino, ARICO, Maurizio, BIONDI, Andrea, GAIPA, Giuseppe, GRAZIA VALSECCHI, Maria, DWORZAK, Michael N, RATEI, Richard, SILVESTRI, Daniela, BENETELLO, Alessandra, BULDINI, Barbara, MAGLIA, Oscar, MASERA, Giuseppe

“…Speed of blast clearance is an indicator of outcome in childhood acute lymphoblastic leukemia (ALL). Availability of measurement of minimal residual disease…”
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Either IL-7 activation of JAK-STAT or BEZ inhibition of PI3K-AKT-mTOR pathways dominates the single-cell phosphosignature of ex vivo treated pediatric T-cell acute lymphoblastic leukemia cells by Kuzilková, Daniela, Bugarin, Cristina, Rejlova, Katerina, Schulz, Axel R, Mei, Henrik E, Paganin, Maddalena, Biffi, Alessandra, Biondi, Andrea, Kalina, Tomas, Gaipa, Giuseppe

“…T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive cancer arising from lymphoblasts of T-cell origin. While TALL accounts for only 15% of childhood…”
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Dasatinib overcomes glucocorticoid resistance in B-cell acute lymphoblastic leukemia by Sarno, Jolanda, Domizi, Pablo, Liu, Yuxuan, Merchant, Milton, Pedersen, Christina Bligaard, Jedoui, Dorra, Jager, Astraea, Nolan, Garry P., Gaipa, Giuseppe, Bendall, Sean C., Bava, Felice-Alessio, Davis, Kara L.

“…Resistance to glucocorticoids (GC) is associated with an increased risk of relapse in B-cell progenitor acute lymphoblastic leukemia (BCP-ALL). Performing…”
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Recurrent ETNK1 mutations in atypical chronic myeloid leukemia by Gambacorti-Passerini, Carlo B., Donadoni, Carla, Parmiani, Andrea, Pirola, Alessandra, Redaelli, Sara, Signore, Giovanni, Piazza, Vincenzo, Malcovati, Luca, Fontana, Diletta, Spinelli, Roberta, Magistroni, Vera, Gaipa, Giuseppe, Peronaci, Marco, Morotti, Alessandro, Panuzzo, Cristina, Saglio, Giuseppe, Usala, Emilio, Kim, Dong-Wook, Rea, Delphine, Zervakis, Konstantinos, Viniou, Nora, Symeonidis, Argiris, Becker, Heiko, Boultwood, Jacqueline, Campiotti, Leonardo, Carrabba, Matteo, Elli, Elena, Bignell, Graham R., Papaemmanuil, Elli, Campbell, Peter J., Cazzola, Mario, Piazza, Rocco

“…Despite the recent identification of recurrent SETBP1 mutations in atypical chronic myeloid leukemia (aCML), a complete description of the somatic lesions…”
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Intravenous infusion of human bone marrow mesenchymal stromal cells promotes functional recovery and neuroplasticity after ischemic stroke in mice by Sammali, Eliana, Alia, Claudia, Vegliante, Gloria, Colombo, Valentina, Giordano, Nadia, Pischiutta, Francesca, Boncoraglio, Giorgio B., Barilani, Mario, Lazzari, Lorenza, Caleo, Matteo, De Simoni, Maria-Grazia, Gaipa, Giuseppe, Citerio, Giuseppe, Zanier, Elisa R.

“…Transplantation of human bone marrow mesenchymal stromal cells (hBM-MSC) promotes functional recovery after stroke in animal models, but the mechanisms…”
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Potency assays and biomarkers for cell-based advanced therapy medicinal products by Capelli, Chiara, Cuofano, Carolina, Pavoni, Chiara, Frigerio, Simona, Lisini, Daniela, Nava, Sara, Quaroni, Michele, Colombo, Valentina, Galli, Francesco, Bezukladova, Svetlana, Panina-Bordignon, Paola, Gaipa, Giuseppe, Comoli, Patrizia, Cossu, Giulio, Martino, Gianvito, Biondi, Andrea, Introna, Martino, Golay, Josée

“…Advanced Therapy Medicinal Products (ATMPs) based on somatic cells expanded , with or without genetic modification, is a rapidly growing area of drug…”
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Phenotypic profiling of CD34 + cells by advanced flow cytometry improves diagnosis of juvenile myelomonocytic leukemia by Bugarin, Cristina, Antolini, Laura, Buracchi, Chiara, Matarraz, Sergio, Coliva, Tiziana Angela, Van der Velden, Vincent H, Szczepanski, Tomasz, Da Costa, Elaine Sobral, Van der Sluijs, Alita, Novakova, Michaela, Mejstrikova, Ester, Nierkens, Stefan, De Mello, Fabiana Vieira, Fernandez, Paula, Aanei, Carmen, Sędek, Łukasz, Strocchio, Luisa, Masetti, Riccardo, Sainati, Laura, Philippé, Jan, Valsecchi, Maria Grazia, Locatelli, Franco, Van Dongen, Jacques J M, Biondi, Andrea, Orfao, Alberto, Gaipa, Giuseppe

“…Diagnostic criteria for juvenile myelomonocytic leukemia (JMML) are currently well defined, however in some patients diagnosis still remains a challenge. Flow…”
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Transposon-Based CAR T Cells in Acute Leukemias: Where are We Going? by Magnani, Chiara F, Tettamanti, Sarah, Alberti, Gaia, Pisani, Ilaria, Biondi, Andrea, Serafini, Marta, Gaipa, Giuseppe

“…Chimeric Antigen Receptor (CAR) T-cell therapy has become a new therapeutic reality for refractory and relapsed leukemia patients and is also emerging as a…”
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Minimal residual disease analysis by eight-color flow cytometry in relapsed childhood acute lymphoblastic leukemia by Karawajew, Leonid, Dworzak, Michael, Ratei, Richard, Rhein, Peter, Gaipa, Giuseppe, Buldini, Barbara, Basso, Giuseppe, Hrusak, Ondrej, Ludwig, Wolf-Dieter, Henze, Günter, Seeger, Karl, von Stackelberg, Arend, Mejstrikova, Ester, Eckert, Cornelia

“…Multiparametric flow cytometry is an alternative approach to the polymerase chain reaction method for evaluating minimal residual disease in treatment…”
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Mutational analysis of ribosomal proteins in a cohort of pediatric patients with T-cell acute lymphoblastic leukemia reveals Q123R, a novel mutation in RPL10 by Bacci, Lorenza, Indio, Valentina, Rambaldelli, Guglielmo, Bugarin, Cristina, Magliocchetti, Franco, Del Rio, Alberto, Pollutri, Daniela, Melchionda, Fraia, Pession, Andrea, Lanciotti, Marina, Dufour, Carlo, Gaipa, Giuseppe, Montanaro, Lorenzo, Penzo, Marianna

“…T-cell acute lymphoblastic leukemia (T-ALL) is a subtype of ALL involving the malignant expansion of T-cell progenitors. It is driven by a number of different…”
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CD20 up-regulation in pediatric B-cell precursor acute lymphoblastic leukemia during induction treatment: setting the stage for anti-CD20 directed immunotherapy by Dworzak, Michael N., Schumich, Angela, Printz, Dieter, Pötschger, Ulrike, Husak, Zvenyslava, Attarbaschi, Andishe, Basso, Giuseppe, Gaipa, Giuseppe, Ratei, Richard, Mann, Georg, Gadner, Helmut

“…CD20 is expressed in approximately one- half of pediatric acute lymphoblastic leukemia (ALL) cases with B-cell precursor (BCP) origin. We observed that it is…”
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Impact of the kinetics of circulating anti-CD19 CAR-T cells and their populations on the outcome of DLBCL patients by Martín-Martín, Lourdes, Gutiérrez-Herrero, Sara, Herrero-García, María, Martín García-Sancho, Alejandro, Yeguas, Ana, Martín-López, Ana-África, López-Corral, Lucía, Pérez-López, Estefanía, García-Blázquez, Marta, Sánchez-Guijo, Fermín, Vidriales, María Belén, Gaipa, Giuseppe, Orfao, Alberto

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P1361: SLEEPING BEAUTY PLATFORM FOR ENGINEERING CAR‐CIK CELLS TOWARD A MULTI‐TARGETING STRATEGY IN B‐ALL by Moretti, Alex, Landoni, Beatrice, Melita, Giusi, Buracchi, Chiara, Ponzo, Marianna, Biondi, Andrea, Gaipa, Giuseppe, Magnani, Chiara

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MesenchymAl stromal cells for Traumatic bRain Injury (MATRIx): a study protocol for a multicenter, double-blind, randomised, placebo-controlled phase II trial by Zanier, Elisa R., Pischiutta, Francesca, Rulli, Eliana, Vargiolu, Alessia, Elli, Francesca, Gritti, Paolo, Gaipa, Giuseppe, Belotti, Daniela, Basso, Gianpaolo, Zoerle, Tommaso, Stocchetti, Nino, Citerio, Giuseppe

“…Background Traumatic brain injury (TBI) is a significant cause of death and disability, with no effective neuroprotective drugs currently available for its…”
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Failure of interferon-γ pre-treated mesenchymal stem cell treatment in a patient with crohn’s disease by Taddio, Andrea, Tommasini, Alberto, Valencic, Erica, Biagi, Ettore, Decorti, Giuliana, De Iudicibus, Sara, Cuzzoni, Eva, Gaipa, Giuseppe, Badolato, Raffaela, Prandini, Alberto, Biondi, Andrea, Ventura, Alessandro

“…Mesenchymal stem cells(MSC) are cells of stromal origin which exhibit unlimited self-renewal capacity and pluripotency in vitro.It has recently been observed…”
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Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia by Bugarin, Cristina, Sarno, Jolanda, Palmi, Chiara, Savino, Angela Maria, te Kronnie, Geertruy, Dworzak, Michael, Shumich, Angela, Buldini, Barbara, Maglia, Oscar, Sala, Simona, Bronzini, Ilaria, Bourquin, Jean-Pierre, Mejstrikova, Ester, Hrusak, Ondrej, Luria, Drorit, Basso, Giuseppe, Izraeli, Shai, Biondi, Andrea, Cazzaniga, Giovanni, Gaipa, Giuseppe

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Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study by Introna, Martino, Borleri, Gianmaria, Conti, Elena, Franceschetti, Marta, Barbui, Anna Maria, Broady, Raewyn, Dander, Erica, Gaipa, Giuseppe, D'Amico, Giovanna, Biagi, Ettore, Parma, Matteo, Pogliani, Enrico M, Spinelli, Orietta, Baronciani, Donatella, Grassi, Anna, Golay, Josee, Barbui, Tiziano, Biondi, Andrea, Rambaldi, Alessandro

“…From the Laboratory of Cellular and Gene Therapy "G. Lanzani", Ospedali Riuniti di Bergamo, Bergamo, Italy (MI, GB, EC, MF, JG); Division of Hematology,…”
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Simultaneous Overexpression of Functional Human HO-1, E5NT and ENTPD1 Protects Murine Fibroblasts against TNF-α-Induced Injury In Vitro by Cinti, Alessandro, De Giorgi, Marco, Chisci, Elisa, Arena, Claudia, Galimberti, Gloria, Farina, Laura, Bugarin, Cristina, Rivolta, Ilaria, Gaipa, Giuseppe, Smolenski, Ryszard Tom, Cerrito, Maria Grazia, Lavitrano, Marialuisa, Giovannoni, Roberto

“…Several biomedical applications, such as xenotransplantation, require multiple genes simultaneously expressed in eukaryotic cells. Advances in genetic…”
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