Search Results - "Gaillard, Natacha"

Changes in seam number and location induce holes within microtubules assembled from porcine brain tubulin and in Xenopus egg cytoplasmic extracts by Guyomar, Charlotte, Bousquet, Clément, Ku, Siou, Heumann, John M, Guilloux, Gabriel, Gaillard, Natacha, Heichette, Claire, Duchesne, Laurence, Steinmetz, Michel O, Gibeaux, Romain, Chrétien, Denis

“…Microtubules are tubes of about 25 nm in diameter that are critically involved in a variety of cellular functions, including motility, compartmentalization,…”
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Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography by Wranik, Maximilian, Weinert, Tobias, Slavov, Chavdar, Masini, Tiziana, Furrer, Antonia, Gaillard, Natacha, Gioia, Dario, Ferrarotti, Marco, James, Daniel, Glover, Hannah, Carrillo, Melissa, Kekilli, Demet, Stipp, Robin, Skopintsev, Petr, Brünle, Steffen, Mühlethaler, Tobias, Beale, John, Gashi, Dardan, Nass, Karol, Ozerov, Dmitry, Johnson, Philip J. M., Cirelli, Claudio, Bacellar, Camila, Braun, Markus, Wang, Meitian, Dworkowski, Florian, Milne, Chris, Cavalli, Andrea, Wachtveitl, Josef, Steinmetz, Michel O., Standfuss, Jörg

“…The binding and release of ligands from their protein targets is central to fundamental biological processes as well as to drug discovery. Photopharmacology…”
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3-nitropyridine analogues as novel microtubule-targeting agents by Herman, Jean, Vanstreels, Els, Bardiot, Dorothée, Prota, Andrea E, Gaillard, Natacha, Gao, Ling-Jie, Vercruysse, Thomas, Persoons, Leentje, Daems, Tinne, Waer, Mark, Herdewijn, Piet, Louat, Thierry, Steinmetz, Michel O, De Jonghe, Steven, Sprangers, Ben, Daelemans, Dirk

“…Microtubule-targeting agents are an important class of anti-cancer drugs; their full potential is however not realized because of significant myelotoxicity and…”
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Structural insight into the stabilization of microtubules by taxanes by Prota, Andrea E, Lucena-Agell, Daniel, Ma, Yuntao, Estevez-Gallego, Juan, Li, Shuo, Bargsten, Katja, Josa-Prado, Fernando, Altmann, Karl-Heinz, Gaillard, Natacha, Kamimura, Shinji, Mühlethaler, Tobias, Gago, Federico, Oliva, Maria A, Steinmetz, Michel O, Fang, Wei-Shuo, Díaz, J Fernando

“…Paclitaxel (Taxol) is a taxane and a chemotherapeutic drug that stabilizes microtubules. While the interaction of paclitaxel with microtubules is well…”
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Inhibiting parasite proliferation using a rationally designed anti‐tubulin agent by Gaillard, Natacha, Sharma, Ashwani, Abbaali, Izra, Liu, Tianyang, Shilliday, Fiona, Cook, Alexander D, Ehrhard, Valentin, Bangera, Mamata, Roberts, Anthony J, Moores, Carolyn A, Morrissette, Naomi, Steinmetz, Michel O

“…Infectious diseases caused by apicomplexan parasites remain a global public health threat. The presence of multiple ligand‐binding sites in tubulin makes this…”
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3-nitropyridine analogues as novel microtubule-targeting agents by Jean Herman, Els Vanstreels, Dorothée Bardiot, Andrea E. Prota, Natacha Gaillard, Ling-Jie Gao, Thomas Vercruysse, Leentje Persoons, Tinne Daems, Mark Waer, Piet Herdewijn, Thierry Louat, Michel O. Steinmetz, Steven De Jonghe, Ben Sprangers, Dirk Daelemans

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