Search Results - "Gaikwad, Nilesh"
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Bileome: The bile acid metabolome of rat
Published in Biochemical and biophysical research communications (10-12-2020)“…Bile acids (BA) play a vital physiological role in vivo. They are not only detergent of dietary lipids and nutrients, but also important hormones or nutrient…”
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Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Profiling of Steroid Metabolome in Human Tissue
Published in Analytical chemistry (Washington) (21-05-2013)“…In humans, steroids play a broad and vital role in regulation of gene expression, secondary sexual characteristics, maturation, reproduction, cardiovascular…”
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Comparative effect of black, green, oolong, and white tea intake on weight gain and bile acid metabolism
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-09-2019)“…•The comparative effects of different teas, prepared from the same fresh leaves, were studied.•The relationship among various teas and their effect on bile…”
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Intracrine Androgens and AKR1C3 Activation Confer Resistance to Enzalutamide in Prostate Cancer
Published in Cancer research (Chicago, Ill.) (01-04-2015)“…The introduction of enzalutamide and abiraterone has led to improvement in the treatment of metastatic castration-resistant prostate cancer. However, acquired…”
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Multiresidue analysis of pesticides in four different pomegranate cultivars: Investigating matrix effect variability by GC-MS/MS and LC-MS/MS
Published in Food chemistry (01-05-2023)“…•Investigated matrix effects in pesticide residue analysis across 4 pomegranate cultivars.•Different cultivars demonstrated different matrix effects for most…”
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Mass spectrometry evidence for formation of estrogen–homocysteine conjugates: Estrogens can regulate homocysteine levels
Published in Free radical biology & medicine (01-12-2013)“…Homocysteine (HCys), a sulfur-containing amino acid, is formed during the metabolism of methionine. An imbalance between the rate of production and the use of…”
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Comparative study on effect of pomegranate peel powder as natural preservative and chemical preservatives on quality and shelf life of muffins
Published in Scientific reports (05-05-2024)“…This research aims to investigate the potential of utilizing pomegranate peel powder (PPP) as a natural preservative in muffin preparation. Pomegranate peel is…”
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Prediction of neonatal morbidity and very preterm delivery using maternal steroid biomarkers in early gestation
Published in PloS one (06-01-2021)“…Preterm delivery is a common pregnancy complication that can result in significant neonatal morbidity and mortality. Limited tools exist to predict preterm…”
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Prefrontal allopregnanolone synergizes with D1 receptor activation to disrupt sensorimotor gating in male Sprague-Dawley rats
Published in Psychopharmacology (01-06-2023)“…Rationale The prepulse inhibition (PPI) of the startle reflex is the best-established index of sensorimotor gating. We documented that the neurosteroid…”
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Pomegranate peel extract as an eco-friendly acid–base indicator and pH indicator paper
Published in Journal of the Iranian Chemical Society (01-04-2024)“…Eco-friendly acid base indicators (anthocyanins) are always a center of attention in quantitative volumetric analysis as substitute for synthetic dye…”
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Metabolomic profiling unravels DNA adducts in human breast that are formed from peroxidase mediated activation of estrogens to quinone methides
Published in PloS one (06-06-2013)“…Currently there are three major hypotheses that have been proposed for estrogen induced carcinogenicity, however exact etiology remains unknown. Based on the…”
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Development of fiber‐enriched muffins using pomegranate peel powder and its effect on physico‐chemical properties and shelf life of the muffins
Published in Journal of the science of food and agriculture (15-03-2024)“…BACKGROUND Pomegranate peel is a by‐product from the pomegranate processing industries and is a rich source of dietary fibers and bioactive compounds. It has…”
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Sex-Dimorphic and Sex Hormone-Dependent Role of Steroid Sulfatase in Adipose Inflammation and Energy Homeostasis
Published in Endocrinology (Philadelphia) (01-09-2018)“…Steroid sulfatase (STS), a desulfating enzyme that converts steroid sulfates to hormonally active steroids, plays an important role in the homeostasis of sex…”
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Cacao use and the San Lorenzo Olmec
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-2011)“…Mesoamerican peoples had a long history of cacao use--spanning more than 34 centuries--as confirmed by previous identification of cacao residues on…”
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Image dataset of pomegranate fruits (Punica granatum) for various machine vision applications
Published in Data in brief (01-08-2021)“…Dataset - an essential aspect and the requirement for any of the machine learning project. Collection / creation of dataset in the agriculture domain is highly…”
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The 5α-reductase inhibitor finasteride reduces opioid self-administration in animal models of opioid use disorder
Published in The Journal of clinical investigation (17-05-2021)“…Opioid use disorder (OUD) has become a leading cause of death in the United States, yet current therapeutic strategies remain highly inadequate. To identify…”
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Estrogen Sulfotransferase Is an Oxidative Stress-responsive Gene That Gender-specifically Affects Liver Ischemia/Reperfusion Injury
Published in The Journal of biological chemistry (05-06-2015)“…Estrogen sulfotransferase (EST) regulates estrogen homeostasis by sulfonating and deactivating estrogens. Liver ischemia and reperfusion (I/R) involves both…”
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Prehispanic use of chili peppers in Chiapas, Mexico
Published in PloS one (13-11-2013)“…The genus Capsicum is New World in origin and represents a complex of a wide variety of both wild and domesticated taxa. Peppers or fruits of Capsicum species…”
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The use and domestication of Theobroma cacao during the mid-Holocene in the upper Amazon
Published in Nature ecology & evolution (01-12-2018)“…Cacao ( Theobroma cacao L.) is an important economic crop, yet studies of its domestication history and early uses are limited. Traditionally, cacao is thought…”
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Genome-wide characterization and development of simple sequence repeat markers for genetic studies in pomegranate (Punica granatum L.)
Published in Trees (Berlin, West) (01-08-2020)“…Key message Genome-wide characterization and development of first set of polymorphic Class I SSRs markers in pomegranate ( Punica granatum L.) through in…”
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