Search Results - "Gai, Chiara"
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Differential Therapeutic Effect of Extracellular Vesicles Derived by Bone Marrow and Adipose Mesenchymal Stem Cells on Wound Healing of Diabetic Ulcers and Correlation to Their Cargoes
Published in International journal of molecular sciences (08-04-2021)“…Extracellular vesicles (EVs) derived from mesenchymal stem cells isolated from both bone marrow (BMSCs) and adipose tissue (ADSCs) show potential therapeutic…”
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2
Salivary extracellular vesicle-associated miRNAs as potential biomarkers in oral squamous cell carcinoma
Published in BMC cancer (18-04-2018)“…Several studies in the past have investigated the expression of micro RNAs (miRNAs) in saliva as potential biomarkers. Since miRNAs associated with…”
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Stem Cell-Derived Extracellular Vesicles and Immune-Modulation
Published in Frontiers in cell and developmental biology (22-08-2016)“…Extra-cellular vesicles (EVs) are bilayer membrane structures enriched with proteins, nucleic acids, and other active molecules and have been implicated in…”
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4
Characterization and Gene Expression Analysis of Serum-Derived Extracellular Vesicles in Primary Aldosteronism
Published in Hypertension (Dallas, Tex. 1979) (01-08-2019)“…Patients affected by primary aldosteronism (PA) display an increased risk of cardiovascular events compared with essential hypertension (EH). Endothelial…”
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Salivary Extracellular Vesicle-Associated exRNA as Cancer Biomarker
Published in Cancers (26-06-2019)“…Extracellular vesicles (EVs) secreted in biological fluids contain several transcripts of the cell of origin, which may modify the functions and phenotype of…”
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Extracellular vesicles in onco-nephrology
Published in Experimental & molecular medicine (15-03-2019)“…Extracellular vesicles (EVs) are important mediators of intercellular communication in cancer and in normal tissues. EVs transfer biologically active molecules…”
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Extracellular Vesicles in Renal Pathophysiology
Published in Frontiers in molecular biosciences (07-06-2017)“…Extracellular vesicles are a heterogeneous population of microparticles released by virtually all living cells which have been recently widely investigated in…”
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Effects of thiamine and fenofibrate on high glucose and hypoxia-induced damage in cell models of the inner blood-retinal barrier
Published in Acta diabetologica (01-12-2020)“…Aims Although diabetic retinopathy has long been considered a microvascular complication, retinal neurodegeneration and inflammation may precede its clinical…”
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Plant-Derived Extracellular Vesicles as a Delivery Platform for RNA-Based Vaccine: Feasibility Study of an Oral and Intranasal SARS-CoV-2 Vaccine
Published in Pharmaceutics (01-03-2023)“…Plant-derived extracellular vesicles (EVs) may represent a platform for the delivery of RNA-based vaccines, exploiting their natural membrane envelope to…”
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Edible Plant-Derived Extracellular Vesicles for Oral mRNA Vaccine Delivery
Published in Vaccines (Basel) (15-02-2024)“…Nucleic acid delivery through extracellular vesicles (EVs) is a well-preserved evolutionary mechanism in all life kingdoms including eukaryotes, prokaryotes,…”
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Bone Marrow Mesenchymal Stromal/Stem Cell-Derived Extracellular Vesicles Promote Corneal Wound Repair by Regulating Inflammation and Angiogenesis
Published in Cells (Basel, Switzerland) (01-12-2022)“…Severe corneal damage leads to complete vision loss, thereby affecting life quality and impinging heavily on the healthcare system. Current clinical approaches…”
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Oral Delivery of mRNA Vaccine by Plant-Derived Extracellular Vesicle Carriers
Published in Cells (Basel, Switzerland) (01-07-2023)“…mRNA-based vaccines were effective in contrasting SARS-CoV-2 infection. However, they presented several limitations of storage and supply chain, and their…”
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13
Noncoding RNAs Carried by Extracellular Vesicles in Endocrine Diseases
Published in International journal of endocrinology (01-01-2018)“…RNA molecules are essential and fine regulators of important biological processes. Their role is well documented also in the endocrine system, both in…”
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Absence of IL-6 Receptor Blockade Effect on the Outcomes of Transplant Glomerulopathy in the Absence of Anti-HLA Donor-specific Antibodies
Published in Transplantation direct (01-06-2024)“…Transplant glomerulopathy (TG) is the hallmark of chronic antibody-mediated rejection but often occurs without anti-HLA donor-specific antibodies (DSAs) in the…”
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Vegetarian dietary guidelines: a comparative dietetic and communicational analysis of eleven international pictorial representations
Published in Revista española de nutrición humana y dietética (16-07-2020)“…Introduction: This study aimed to analyze the main pictorial representations of food-based vegetarian dietary guidelines from different countries as a starting…”
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Molecular and functional characterization of circulating extracellular vesicles from diabetic patients with and without retinopathy and healthy subjects
Published in Experimental eye research (01-11-2018)“…Diabetic retinopathy is a sight-threatening complication of diabetes, characterized by loss of retinal pericytes and abnormal angiogenesis. We previously…”
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Functional analysis of miR-21-3p, miR-30b-5p and miR-150-5p shuttled by extracellular vesicles from diabetic subjects reveals their association with diabetic retinopathy
Published in Experimental eye research (01-07-2019)“…Microvascular dysfunctions due to altered interactions between endothelial cells (ECs) and pericytes are key-events in the pathogenesis of diabetic…”
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Early effects of first‐line treatment with anti‐interleukin‐6 receptor antibody tocilizumab for chronic active antibody‐mediated rejection in kidney transplantation
Published in Clinical transplantation (01-08-2020)“…Introduction Chronic active antibody‐mediated rejection (cAMR) is a major determinant of late allograft failure. Rituximab/immunoglobulins (IVIg) + plasma…”
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Extracellular vesicle-mediated modulation of angiogenesis
Published in Histology and histopathology (01-04-2016)“…Angiogenesis is a tightly regulated process where a number of different players are involved. Recently, a role for membrane vesicles actively released from…”
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PDGF-BB Carried by Endothelial Cell-Derived Extracellular Vesicles Reduces Vascular Smooth Muscle Cell Apoptosis in Diabetes
Published in Diabetes (New York, N.Y.) (01-04-2018)“…Endothelial cell-derived extracellular vesicles (CD31EVs) constitute a new entity for therapeutic/prognostic purposes. The roles of CD31EVs as mediators of…”
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