Search Results - "Gahler, Roland"
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Effect on Insulin, Glucose and Lipids in Overweight/Obese Australian Adults of 12 Months Consumption of Two Different Fibre Supplements in a Randomised Trial
Published in Nutrients (29-01-2017)“…Higher fibre intakes are associated with risk reduction for chronic diseases. This study investigated the effects of supplementation with PolyGlycopleX (PGX),…”
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Differences in Metabolite Profiles of Dihydroberberine and Micellar Berberine in Caco-2 Cells and Humans-A Pilot Study
Published in International journal of molecular sciences (22-05-2024)“…We investigated the pharmacokinetic pathway of berberine and its metabolites in vitro, in Caco-2 cells, and in human participants following the administration…”
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A Comparison and Safety Evaluation of Micellar versus Standard Vitamin D3 Oral Supplementation in a Randomized, Double-Blind Human Pilot Study
Published in Nutrients (22-05-2024)“…The aim of this pilot study was to evaluate and compare bioavailability and safety of two Vitamin D3 formulations (softgels) in healthy adults, at single daily…”
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Effect of Fibre Supplementation on Body Weight and Composition, Frequency of Eating and Dietary Choice in Overweight Individuals
Published in Nutrients (16-02-2017)“…Fibre supplementation can potentially reduce energy intake and contribute to weight loss. The mechanism may be reduced frequency of eating, resulting in…”
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Effect of a functional fibre supplement on glycemic control when added to a year-long medically supervised weight management program in adults with type 2 diabetes
Published in European journal of nutrition (01-04-2021)“…Purpose Soluble fibre beneficially affects metabolism but whether it can augment the reductions in glycemia induced through intensive weight management has not…”
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A Pharmacokinetic Study of Different Quercetin Formulations in Healthy Participants: A Diet-Controlled, Crossover, Single- and Multiple-Dose Pilot Study
Published in Evidence-based complementary and alternative medicine (01-01-2023)“…This study aimed to evaluate the blood concentrations of quercetin in healthy participants after the administration of different formulations in single- and…”
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Effect on body weight and composition in overweight/obese Australian adults over 12 months consumption of two different types of fibre supplementation in a randomized trial
Published in Nutrition & metabolism (17-11-2016)“…Higher fibre intakes are associated with risk reduction for chronic diseases. However, many people find difficulty in consuming sufficient fibre through their…”
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Effect of training on the reliability of satiety evaluation and use of trained panellists to determine the satiety effect of dietary fibre: a randomised controlled trial
Published in PloS one (15-05-2015)“…The assessment of satiety effects on foods is commonly performed by untrained volunteers marking their perceived hunger or fullness on line scales, marked with…”
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Characterization and Pharmacokinetic Assessment of a New Berberine Formulation with Enhanced Absorption In Vitro and in Human Volunteers
Published in Pharmaceutics (01-11-2023)“…Berberine is a plant-origin quaternary isoquinoline alkaloid with a vast array of biological activities, including antioxidant and blood-glucose- and…”
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Combining sitagliptin/metformin with a functional fiber delays diabetes progression in Zucker rats
Published in Journal of endocrinology (01-03-2014)“…Our primary objective was to determine whether administering the viscous and fermentable polysaccharide PolyGlycopleX (PGX) with metformin (MET) or…”
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A randomized, double-blind, placebo-controlled, cross-over trial to evaluate the effect of EstroSense ® on 2-hydroxyestrone:16α-hydroxyestrone ratio in premenopausal women
Published in Journal of complementary & integrative medicine (01-03-2023)“…Some estrogen metabolites are associated with increased breast cancer risk, while others are protective. Research efforts have focused on modifiable factors,…”
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Micronutrient status of individuals with overweight and obesity following 3 months' supplementation with PolyGlycopleX (PGX®) or psyllium: a randomized controlled trial
Published in BMC nutrition (03-05-2022)“…Safe and effective weight control strategies are needed to curtail the current obesity epidemic worldwide. Increasing dietary fibre has shown positive results…”
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Evaluation of the Metabolite Profile of Fish Oil Omega-3 Fatty Acids (n-3 FAs) in Micellar and Enteric-Coated Forms-A Randomized, Cross-Over Human Study
Published in Metabolites (01-05-2024)“…This study evaluated the differences in the metabolite profile of three n-3 FA fish oil formulations in 12 healthy participants: (1) standard softgels (STD)…”
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Effect of the novel polysaccharide PolyGlycopleX® on short-chain fatty acid production in a computer-controlled in vitro model of the human large intestine
Published in Nutrients (14-03-2014)“…Many of the health benefits associated with dietary fiber are attributed to their fermentation by microbiota and production of short chain fatty acids (SCFA)…”
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Consumption of the Soluble Dietary Fibre Complex PolyGlycopleX(®) Reduces Glycaemia and Increases Satiety of a Standard Meal Postprandially
Published in Nutrients (06-05-2016)“…The effect of consumption of PolyGlycopleX(®) (PGX(®)) was compared to wheat dextrin (WD) in combination with a standard meal, on postprandial satiety and…”
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Studies on macromolecular interactions in ternary mixtures of konjac glucomannan, xanthan gum and sodium alginate
Published in Carbohydrate polymers (2011)“…Covalent and non-covalent macromolecular interactions were studied in the proprietary commercial product, PGX ® (PolyGlycopleX ®) which is manufactured from…”
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Changes in Visceral Adiposity and Serum Cholesterol with a Novel Viscous Polysaccharide in Japanese Adults with Abdominal Obesity
Published in Obesity (Silver Spring, Md.) (01-09-2013)“…Objective: Evidence supports the role of dietary fiber in improving metabolic health. PolyGlycopleX® (PGX®), a viscous functional polysaccharide improves…”
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Effect of PolyGlycopleX (PGX) Consumption on Blood Lipid Profiles in Healthy, Low CVD Risk Overweight Adults
Published in Nutrients (27-03-2019)“…Raised blood lipid levels are associated with a risk of a cardiovascular disease (CVD). Moderate reductions in several CVD factors such as total, low-density…”
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Dose–response effect of a novel functional fibre, PolyGlycopleX®, PGX®, on satiety
Published in Appetite (01-06-2014)“…•A satiety dose–response effect of 2.5 and 7.5 g PGX® consumed at breakfast was found.•A 34% increase in fullness compared with the inulin control was provided…”
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Effects of added PGX®, a novel functional fibre, on the glycaemic index of starchy foods
Published in British journal of nutrition (28-07-2012)“…The development of lower-glycaemic index (GI) foods requires simple, palatable and healthy strategies. The objective of the present study was to determine the…”
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