Search Results - "Gahery, Hanne"

Adenovirus Hexon Protein Is a Potent Adjuvant for Activation of a Cellular Immune Response by Molinier-Frenkel, Valérie, Lengagne, Renée, Gaden, Florence, Hong, Saw-See, Choppin, Jeannine, Gahery-Ségard, Hanne, Boulanger, Pierre, Guillet, Jean-Gérard

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Recognition of a Subregion of Human Proinsulin by Class I-Restricted T Cells in Type 1 Diabetic Patients by Toma, Andréa, Haddouk, Samy, Briand, Jean-Paul, Camoin, Luc, Gahery, Hanne, Connan, Francine, Dubois-Laforgue, Danielle, Caillat-Zucman, Sophie, Guillet, Jean-Gérard, Carel, Jean-Claude, Muller, Sylviane, Choppin, Jeannine, Boitard, Christian, McDevitt, Hugh O.

“…Proinsulin is a key autoantigen in type 1 diabetes. Evidence in the mouse has underscored the importance of the insulin B chain region in autoimmunity to…”
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HLA-DP4, the Most Frequent HLA II Molecule, Defines a New Supertype of Peptide-Binding Specificity by Castelli, Florence A, Buhot, Cecile, Sanson, Alain, Zarour, Hassane, Pouvelle-Moratille, Sandra, Nonn, Celine, Gahery-Segard, Hanne, Guillet, Jean-Gerard, Menez, Andre, Georges, Bertrand, Maillere, Bernard

“…Among HLA-DP specificities, HLA-DP4 specificity involves at least two molecules, HLA-DPA1*0103/DPB1*0401 (DP401) and HLA-DPA1*0103/DPB1*0402 (DP402), which…”
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The Uterine Immune Profile May Help Women With Repeated Unexplained Embryo Implantation Failure After In Vitro Fertilization by Lédée, Nathalie, Petitbarat, Marie, Chevrier, Lucie, Vitoux, Dominique, Vezmar, Katia, Rahmati, Mona, Dubanchet, Sylvie, Gahéry, Hanne, Bensussan, Armand, Chaouat, Gerard

“…Labeled problem Embryo implantation remains the main limiting factor in assisted reproductive medicine (20% success rate). Methods of study An endometrial…”
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Cellular immune responses induced with dose-sparing intradermal administration of HIV vaccine to HIV-uninfected volunteers in the ANRS VAC16 trial by Launay, Odile, Durier, Christine, Desaint, Corinne, Silbermann, Benjamin, Jackson, Angela, Pialoux, Gilles, Bonnet, Bénédicte, Poizot-Martin, Isabelle, Gonzalez-Canali, Gustavo, Cuzin, Lise, Figuereido, Suzanne, Surenaud, Mathieu, Ben Hamouda, Nadine, Gahery, Hanne, Choppin, Jeannine, Salmon, Dominique, Guérin, Corinne, Bourgault Villada, Isabelle, Guillet, Jean-Gérard

“…The objective was to compare the safety and cellular immunogenicity of intradermal versus intramuscular immunization with an HIV-lipopeptide candidate vaccine…”
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Immunological Responses and Long-Term Treatment Interruption after Human Immunodeficiency Virus Type 1 (HIV-1) Lipopeptide Immunization of HIV-1-Infected Patients: the LIPTHERA Study by Pialoux, Gilles, Quercia, Romina P, Gahery, Hanne, Daniel, Nathalie, Slama, Laurence, Girard, Pierre-Marie, Bonnard, Philippe, Rozenbaum, Willy, Schneider, Véronique, Salmon, Dominique, Guillet, Jean-Gérard

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Immune Response to Recombinant Adenovirus in Humans: Capsid Components from Viral Input Are Targets for Vector-Specific Cytotoxic T Lymphocytes by Molinier-Frenkel, V, Gahery-Segard, H, Mehtali, M, Le Boulaire, C, Ribault, S, Boulanger, P, Tursz, T, Guillet, J G, Farace, F

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Immune Response to Recombinant Capsid Proteins of Adenovirus in Humans: Antifiber and Anti-Penton Base Antibodies Have a Synergistic Effect on Neutralizing Activity by Gahéry-Ségard, H, Farace, F, Godfrin, D, Gaston, J, Lengagne, R, Tursz, T, Boulanger, P, Guillet, J G

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Long-Term Specific Immune Responses Induced in Humans by a Human Immunodeficiency Virus Type 1 Lipopeptide Vaccine: Characterization of CD8+-T-Cell Epitopes Recognized by Gahéry-Ségard, Hanne, Pialoux, Gilles, Figueiredo, Suzanne, Igéa, Céline, Surenaud, Mathieu, Gaston, Jessintha, Gras-Masse, Helene, Lévy, Jean-Paul, Guillet, Jean-Gérard

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Multiepitopic B- and T-Cell Responses Induced in Humans by a Human Immunodeficiency Virus Type 1 Lipopeptide Vaccine by Gahéry-Ségard, H, Pialoux, G, Charmeteau, B, Sermet, S, Poncelet, H, Raux, M, Tartar, A, Lévy, J P, Gras-Masse, H, Guillet, J G

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Distinct Roles of Adenovirus Vector-Transduced Dendritic Cells, Myoblasts, and Endothelial Cells in Mediating an Immune Response against a Transgene Product by Mercier, Stéphanie, Gahéry-Segard, Hanne, Monteil, Martine, Lengagne, Renée, Guillet, Jean-Gérard, Eloit, Marc, Denesvre, Caroline

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Memory CD8+ T cells elicited by HIV-1 lipopeptide vaccines display similar phenotypic profiles but differences in term of magnitude and multifunctionality compared with FLU- or EBV-specific memory T cells in humans by Figueiredo, Suzanne, Charmeteau, Benedicte, Surenaud, Mathieu, Salmon, Dominique, Launay, Odile, Guillet, Jean-Gérard, Hosmalin, Anne, Gahery, Hanne

“…Highlights • Specific-CD8+ T cells are crucial in HIV vaccines designed to generate cell immunity. • We fully characterized HIV-specific memory CD8+ T cell…”
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New CD4+ and CD8+ T cell responses induced in chronically HIV type-1-infected patients after immunizations with an HIV type 1 lipopeptide vaccine by Gahery, Hanne, Daniel, Nathalie, Charmeteau, Bénédicte, Ourth, Lucie, Jackson, Angéla, Andrieu, Muriel, Choppin, Jeannine, Salmon, Dominique, Pialoux, Gilles, Guillet, Jean-Gerard

“…We showed that an anti-HIV lipopeptide vaccine injected to HIV-uninfected volunteers was well tolerated and able to induce a specific CD4(+) and CD8(+) T cell…”
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Lipopeptide‐based melanoma cancer vaccine induced a strong MART‐27‐35‐cytotoxic T lymphocyte response in a preclinal study by Le Gal, Frédérique‐Anne, Prevost‐Blondel, Armelle, Lengagne, Renée, Bossus, Marc, Farace, Françoise, Chaboissier, Aude, Gras‐Masse, Hélène, Engelhard, Victor H., Guillet, Jean‐Gérard, Gahéry‐Ségard, Hanne

“…Identification of tumor antigens and their optimal antigenic peptides raised hopes for the development of peptide‐based immunotherapeutic vaccine strategies…”
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Lipopeptides induce cell-mediated anti-HIV immune responses in seronegative volunteers by PIALOUX, Gilles, GAHERY-SEGARD, Hanne, SERMET, Sandrine, PONCELET, Hubert, FOURNIER, Sandra, GERARD, Laurence, TARTAR, André, GRAS-MASSE, Hélène, LEVY, Jean Paul, GUILLET, Jean Gérard

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Immunological and virological efficacy of a therapeutic immunization combined with interleukin-2 in chronically HIV-1 infected patients by LEVY, Yves, GAHERY-SEGARD, Hanne, DELFRAISSY, Jean-Francois, ABOULKER, Jean-Pierre, DURIER, Christine, LASCAUX, Anne-Sophie, GOUJARD, Cécile, MEIFFREDY, Vincent, ROUZIOUX, Christine, EL HABIB, Raphaëlle, BEUMONT-MAUVIEL, Maria, GUILLET, Jean-Gérard

“…Several lines of evidence suggest that the immune system may control HIV-1 replication, but that it could fail in the long term. Strategies aimed to elicit…”
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Sustained control of viremia following therapeutic immunization in chronically HIV-1-infected individuals by LEVY, Yves, DURIER, Christine, DELFRAISSY, Jean-Francois, ABOULKER, Jean-Pierre, LASCAUX, Anne-Sophie, MEIFFREDY, Vincent, GAHERY-SEGARD, Hanne, GOUJARD, Cécile, ROUZIOUX, Christine, RESCH, Martine, GUILLET, Jean-Gérard, KAZATCHKINE, Michel

“…Viral rebounds inevitably follow interruption of antiretroviral treatment in HIV-1-infected individuals. The randomized ANRS 093 aimed at investigating whether…”
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HLA-DR-restricted peptides identified in the Nef protein can induce HIV type 1-specific IL-2/IFN-gamma-secreting CD4+ and CD4+ /CD8+ T cells in humans after lipopeptide vaccination by Gahery, Hanne, Figueiredo, Suzanne, Texier, Catherine, Pouvelle-Moratille, Sandra, Ourth, Lucie, Igea, Céline, Surenaud, Mathieu, Guillet, Jean-Gérard, Maillere, Bernard

“…We screened the Neflaiprotein to identify new HLA-DR-restricted epitopes, because this small protein is expressed early during infection, and specific CD4(+) T…”
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HIV preventive vaccine research at the ANRS: the lipopeptide vaccine approach by Gahery, Hanne, Choppin, Jeannine, Bourgault, Isabelle, Fischer, Elizabeth, Maillère, Bernard, Guillet, Jean-Gèrard

“…The HIV (human immunodeficiency virus)/AIDS epidemic is of unprecedented gravity and is spreading rapidly, notably in the most disadvantaged regions of the…”
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Humoral immune response to the capsid components of recombinant adenoviruses: routes of immunization modulate virus-induced Ig subclass shifts by Gahéry-Ségard, H, Juillard, V, Gaston, J, Lengagne, R, Pavirani, A, Boulanger, P, Guillet, J G

“…This study examines in detail the capsid-specific humoral immune response of BALB/c mice after one single injection of a replication-defective adenovirus. Two…”
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