Search Results - "Gahan, Lawrence. R."

Rhodium catalyzed template-assisted distal para -C-H olefination by Dutta, Uttam, Maiti, Sudip, Pimparkar, Sandeep, Maiti, Siddhartha, Gahan, Lawrence R, Krenske, Elizabeth H, Lupton, David W, Maiti, Debabrata

“…Rhodium catalysis has been extensively used for -C-H functionalization reactions, and successfully extended to -C-H functionalization. Its application to -C-H…”
Get full text

The Catalytic Mechanisms of Binuclear Metallohydrolases by Mitić, Nataša, Smith, Sarah J, Neves, Ademir, Guddat, Luke W, Gahan, Lawrence R, Schenk, Gerhard

“…Binuclear metallohydrolases are a structurally diverse group of enzymes that use binuclear metal ion centers to catalyze the hydrolysis of amides and esters of…”
Get full text

The organophosphate-degrading enzyme from Agrobacterium radiobacter displays mechanistic flexibility for catalysis by Ely, Fernanda, Hadler, Kieran S, Gahan, Lawrence R, Guddat, Luke W, Ollis, David L, Schenk, Gerhard

“…The OP (organophosphate)-degrading enzyme from Agrobacterium radiobacter (OpdA) is a binuclear metallohydrolase able to degrade highly toxic OP pesticides and…”
Get more information

Synthesis, Magnetic Properties, and Phosphoesterase Activity of Dinuclear Cobalt(II) Complexes by Daumann, Lena J, Comba, Peter, Larrabee, James A, Schenk, Gerhard, Stranger, Robert, Cavigliasso, German, Gahan, Lawrence R

“…A series of dinuclear cobalt(II) complexes has been prepared and characterized to generate functional and spectroscopic models for cobalt(II) substituted…”
Get full text

Cadmium(II) Complexes: Mimics of Organophosphate Pesticide Degrading Enzymes and Metallo-β-lactamases by Daumann, Lena J, Gahan, Lawrence. R, Comba, Peter, Schenk, Gerhard

“…Cadmium(II) complexes of ethyl 4-hydroxy-3,5-bis(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)benzoate (CO2EtH3 L1) and ethyl…”
Get full text

Spectroscopic Characterization of the Active FeIIIFeIII and FeIIIFeII Forms of a Purple Acid Phosphatase Model System by Comba, Peter, Gahan, Lawrence R, Mereacre, Valeriu, Hanson, Graeme R, Powell, Annie K, Schenk, Gerhard, Zajaczkowski-Fischer, Marta

“…Two new dinucleating ligands (H3L2 and HL3), derivatives of a well-known dinucleating ligand (HL1) with two bis-picolylamine sites connected to a bridging…”
Get full text

Phosphatase reactivity of a dicopper(II) complex of a patellamide derivative--possible biological functions of cyclic pseudopeptides by Comba, Peter, Gahan, Lawrence R, Hanson, Graeme R, Westphal, Michael

“…A possible biological function of cyclic pseudo-octapeptides is presented. The dinuclear copper(II) complex of a synthetic analogue…”
Get more information

Electronic Structure and Spectro-Structural Correlations of FeIIIZnII Biomimetics for Purple Acid Phosphatases: Relevance to DNA Cleavage and Cytotoxic Activity by Peralta, Rosely A, Bortoluzzi, Adailton J, de Souza, Bernardo, Jovito, Rafael, Xavier, Fernando R, Couto, Ricardo A. A, Casellato, Annelise, Nome, Faruk, Dick, Andrew, Gahan, Lawrence. R, Schenk, Gerhard, Hanson, Graeme R, de Paula, Flávia C. S, Pereira-Maia, Elene C, de P. Machado, Sergio, Severino, Patricia C, Pich, Claus, Bortolotto, Tiago, Terenzi, Hernán, Castellano, Eduardo E, Neves, Ademir, Riley, Mark J

“…Purple acid phosphatases (PAPs) are a group of metallohydrolases that contain a dinuclear FeIIIMII center (MII = Fe, Mn, Zn) in the active site and are able to…”
Get full text

Structural Flexibility Enhances the Reactivity of the Bioremediator Glycerophosphodiesterase by Fine-Tuning Its Mechanism of Hydrolysis by Hadler, Kieran S, Mitić, Nataša, Ely, Fernanda, Hanson, Graeme R, Gahan, Lawrence R, Larrabee, James A, Ollis, David L, Schenk, Gerhard

“…The glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) belongs to the family of binuclear metallohydrolases and has attracted recent attention due to…”
Get full text

Copper(II) Complexes of a Hexadentate Mixed-Donor N3S3 Macrobicyclic Cage: Facile Rearrangements and Interconversions by Bell, Craig A., Bernhardt, Paul V., Gahan, Lawrence R., Martínez, Manuel, Monteiro, Michael J., Rodríguez, Carlos, Sharrad, Clint A.

“…The potentially hexadentate mixed‐donor cage ligand 1‐methyl‐8‐amino‐3,13,16‐trithia‐6,10,19‐triazabicyclo[6.6.6]eicosane (AMME‐N3S3sar; sar=sarcophagine)…”
Get full text

Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase by Schenk, G, Gahan, L.R, Carrington, L.E, Mitic, N, Valizadeh, M, Hamilton, S.E, de Jersey, J, Guddat, L.W

“…Purple acid phosphatases (PAPs) are a family of binuclear metalloenzymes that catalyze the hydrolysis of phosphoric acid esters and anhydrides. A PAP in sweet…”
Get full text

Dinuclear Zinc(II) Complexes with Hydrogen Bond Donors as Structural and Functional Phosphatase Models by Bosch, Simone, Comba, Peter, Gahan, Lawrence R, Schenk, Gerhard

“…It is becoming increasingly apparent that the secondary coordination sphere can have a crucial role in determining the functional properties of biomimetic…”
Get full text

Copper(II) Coordination Chemistry of Westiellamide and Its Imidazole, Oxazole, and Thiazole Analogues by Comba, Peter, Gahan, Lawrence R., Haberhauer, Gebhard, Hanson, Graeme R., Noble, Christopher J., Seibold, Björn, van den Brenk, Anna L.

“…The copper(II) coordination chemistry of westiellamide (H3Lwa), as well as of three synthetic analogues with an [18]azacrown‐6 macrocyclic structure but with…”
Get full text

Synthesis, Magnetic Properties, and Catalytic Properties of a Nickel(II)-Dependent Biomimetic of Metallohydrolases by Horn, Jr, Adolfo, Englert, Daniel, Roberts, Asha E, Comba, Peter, Schenk, Gerhard, Krenske, Elizabeth H, Gahan, Lawrence R

“…A dinickel(II) complex of the ligand 1,3-bis(bis(pyridin-2-ylmethyl)amino)propan-2-ol (HL1) has been prepared and characterized to generate a functional model…”
Get full text

Chelated O2BOH2– or Chelated O2CO2–: An Isoelectronic Conundrum by Ismael, Fouad, Fleming, Cassandra L., Gahan, Lawrence R., Blackman, Allan G

“…The species originally reported as [Co­(bipy)2O2BOH]·[B5O6(OH)4]·H3BO3·H3O·H2O, a Co­(II) complex containing a chelated O2BOH2– ligand, is shown to be…”
Get full text

The ascidian Lissoclinum patella, the patellamides and copper by Baur, Philipp, Comba, Peter, Gahan, Lawrence R, Scholz, Christian

“…The ascidian species Lissoclinum patella is found, amongst other places, around Heron Island on the Great Barrier Reef, Australia. L. patella has a…”
Get full text

Mutation of outer-shell residues modulates metal ion co-ordination strength in a metalloenzyme by Foo, Jee-Loon, Jackson, Colin J, Carr, Paul D, Kim, Hye-Kyung, Schenk, Gerhard, Gahan, Lawrence R, Ollis, David L

“…The metal ion co-ordination sites of many metalloproteins have been characterized by a variety of spectroscopic techniques and small-molecule model systems,…”
Get more information

Spectroscopic and mechanistic studies of dinuclear metallohydrolases and their biomimetic complexes by Daumann, Lena J, Schenk, Gerhard, Ollis, David L, Gahan, Lawrence R

“…An enhanced understanding of the metal ion binding and active site structural features of phosphoesterases such as the glycerophosphodiesterase from…”
Get more information

Steric Activation in the Nazarov Cyclization of Fully Substituted Divinyl Ketones by Flynn, Bernard Luke, Chen, Shuqi, Keto, Angus B, El-Hawli, Ahmad, Gahan, Lawrence R, White, Jonathan M, Krenske, Elizabeth H

“…Fully substituted divinyl ketones (fsDVKs) have long been regarded as resistant to Nazarov cyclization (NC) unless they contain strategically positioned…”
Get full text

Biomimetics for purple acid phosphatases: A historical perspective by Wilson, Liam A., Pedroso, Marcelo M., Peralta, Rosely A., Gahan, Lawrence R., Schenk, Gerhard

“…Biomimetics hold potential for varied applications in biotechnology and medicine but have also attracted particular interest as benchmarks for the functional…”
Get full text