Search Results - "Gagnon, Edith"

Molecular effect of an OPTN common variant associated to Paget's disease of bone by Silva, Iris A L, Conceição, Natércia, Gagnon, Édith, Brown, Jacques P, Cancela, M Leonor, Michou, Laëtitia

“…Paget's disease of bone (PDB) is a chronic bone disorder and although genetic factors appear to play an important role in its pathogenesis, to date PDB causing…”
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Effect of genetic variants of OPTN in the pathophysiology of Paget's disease of bone by Silva, Iris A.L., Conceição, Natércia, Gagnon, Édith, Caiado, Helena, Brown, Jacques P., Gianfrancesco, Fernando, Michou, Laëtitia, Cancela, M. Leonor

“…Paget's disease of bone (PDB) is the second most frequent metabolic bone disease after osteoporosis. Genetic factors play an important role in PDB, but to date…”
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Attenuated clinical and osteoclastic phenotypes of Paget's disease of bone linked to the p.Pro392Leu/SQSTM1 mutation by a rare variant in the DOCK6 gene by Dessay, Mariam, Couture, Emile, Maaroufi, Halim, Fournier, Frédéric, Gagnon, Edith, Droit, Arnaud, Brown, Jacques P, Michou, Laëtitia

“…We identified two families with Paget's disease of bone (PDB) linked to the p.Pro392Leu mutation within the SQSTM1 gene displaying a possible digenism. This…”
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Effect of a rare genetic variant of TM7SF4 gene on osteoclasts of patients with Paget's disease of bone by Laurier, Emilie, Amiable, Nathalie, Gagnon, Edith, Brown, Jacques P, Michou, Laëtitia

“…Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) is involved in osteoclastogenesis with a key role in mononucleated osteoclasts fusion. We reported in…”
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Molecular test of Paget's disease of bone in families not linked to SQSTM1 gene mutations by You, Yang, Simonyan, David, Bureau, Alexandre, Gagnon, Edith, Albert, Caroline, Guertin, Jason R., Tarride, Jean-Eric, Brown, Jacques P., Michou, Laëtitia

“…Paget's disease of bone (PDB) is a focal metabolic bone disorder characterized by an increased bone remodeling. Fifteen to 40 % of PDB patients have a familial…”
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Novel SQSTM1 mutations in patients with Paget's disease of bone in an unrelated multiethnic American population by Michou, Laëtitia, Morissette, Jean, Gagnon, Edith R, Marquis, Anik, Dellabadia, Maryann, Brown, Jacques P, Siris, Ethel S

“…Abstract More than 20 mutations of the Sequestosome 1 ( SQSTM1 ) gene have been reported in patients of European descent affected by Paget's disease of bone…”
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Clinical phenotype of adult offspring carriers of the p.Pro392Leu mutation within the SQSTM1 gene in Paget's disease of bone by Dessay, Mariam, Jobin Gervais, François, Simonyan, David, Samson, Andréanne, Gleeton, Guylaine, Gagnon, Edith, Albert, Caroline, Brown, Jacques P., Michou, Laëtitia

“…Paget's disease of bone (PDB) is a common chronic bone disorder. In the French-Canadian population, the p.Pro392Leu mutation within the SQSTM1 gene is involved…”
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Identification of Key Functional Domains in the C Terminus of the K+-Cl– Cotransporters by Bergeron, Marc J., Gagnon, Édith, Caron, Luc, Isenring, Paul

“…The K+-Cl– cotransporter (KCC) isoforms constitute a functionally heterogeneous group of ion carriers. Emerging evidence suggests that the C terminus (Ct) of…”
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Functional comparison of renal Na-K-Cl cotransporters between distant species by Gagnon, Edith, Forbush, Biff, Caron, Luc, Isenring, Paul

“…In the shark (sa), two variants of the renal Na-K-Cl cotransporter (saNKCC2A and saNKCC2F) are produced by alternative splicing of the second transmembrane…”
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Three-dimensional Culture System as a Model for Studying Cancer Cell Invasion Capacity and Anticancer Drug Sensitivity by DOILLON, Charles J, GAGNON, Edith, PARADIS, Renée, KOUTSILIERIS, Michael

“…Background: Three-dimensional (3-D) culture systems that simulate the tumor extracellular microenvironment may be appropriate to test cancer cell potential for…”
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Ammonium transport and pH regulation by K(+)-Cl(-) cotransporters by Bergeron, Marc J, Gagnon, Edith, Wallendorff, Bernadette, Lapointe, Jean-Yves, Isenring, Paul

“…The Na(+)-K(+)-Cl(-) cotransporters (NKCCs), which belong to the cation-Cl(-) cotransporter (CCC) family, are able to translocate NH4(+) across cell membranes…”
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Molecular mechanisms of cation transport by the renal Na+-K+-Cl- cotransporter: structural insight into the operating characteristics of the ion transport sites by Gagnon, Edith, Bergeron, Marc J, Daigle, Nikolas D, Lefoll, Marie-Hélène, Isenring, Paul

“…Two variants of the renal Na(+)-K(+)-Cl(-) cotransporter (NKCC2), called NKCC2A and NKCC2F, display marked differences in Na(+), Rb(+), and Cl(-) affinities,…”
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Protection from Group B Streptococcal Infection in Neonatal Mice by Maternal Immunization with Recombinant Sip Protein by MARTIN, Denis, RIOUX, Stéphane, GAGNON, Edith, BOYER, Martine, HAMEL, Josée, CHARLAND, Nathalie, BRODEUR, Bernard R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Functional and molecular characterization of the shark renal Na-K-Cl cotransporter: novel aspects by Gagnon, Edith, Forbush, Biff, Flemmer, Andreas W, Giménez, Ignacio, Caron, Luc, Isenring, Paul

“…The Na-K-Cl cotransporter isoform 1 (NKCC1) has been isolated from several species, including Squalus acanthias. A second kidney-specific isoform (NKCC2) has…”
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Molecular mechanisms of Cl- transport by the renal Na(+)-K(+)-Cl- cotransporter. Identification of an intracellular locus that may form part of a high affinity Cl(-)-binding site by Gagnon, Edith, Bergeron, Marc J, Brunet, Geneviève M, Daigle, Nikolas D, Simard, Charles F, Isenring, Paul

“…The 2nd transmembrane domain (tm) of the secretory Na(+)-K(+)-Cl(-) cotransporter (NKCC1) and of the kidney-specific isoform (NKCC2) has been shown to play an…”
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Gene-environment interactions in Paget's disease of bone by Numan, Mohamed S., Jean, Sonia, Dessay, Mariam, Gagnon, Edith, Amiable, Nathalie, Brown, Jacques P., Michou, Laëtitia

“…This study explored the role of outdoor and indoor air pollutants in Paget's disease of bone (PDB). We performed a survey in 140 French-Canadian patients with…”
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Cloning and Functional Characterization of a Cation-Cl− Cotransporter-interacting Protein by Caron, Luc, Rousseau, François, Gagnon, Édith, Isenring, Paul

“…To date, the cation-Cl−cotransporter (CCC) family comprises two branches of homologous membrane proteins. One branch includes the Na+-K+-Cl− cotransporters…”
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Identification of rare genetic variants in novel loci associated with Paget’s disease of bone by Beauregard, Mariejka, Gagnon, Edith, Guay-Bélanger, Sabrina, Morissette, Jean, Brown, Jacques P., Michou, Laëtitia

“…In genome-wide association studies, single nucleotide polymorphisms located in five novel loci were associated with PDB. We aimed at identifying rare genetic…”
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Development of a molecular test of Paget's disease of bone by Guay-Bélanger, Sabrina, Simonyan, David, Bureau, Alexandre, Gagnon, Edith, Albert, Caroline, Morissette, Jean, Siris, Ethel S, Orcel, Philippe, Brown, Jacques P, Michou, Laëtitia

“…Abstract Depending on populations, 15 to 40% of patients have a familial form of Paget's disease of bone (PDB), which is transmitted in an autosomal-dominant…”
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Human angiomotin-like 1 associates with an angiomotin protein complex through its coiled-coil domain and induces the remodeling of the actin cytoskeleton by Gagné, Valérie, Moreau, Julie, Plourde, Mélodie, Lapointe, Mathieu, Lord, Mathieu, Gagnon, Édith, Fernandes, Maria J. G.

“…Angiostatin is a potent inhibitor of angiogenesis. One mechanism through which angiostatin inhibits angiogenesis is by binding to the cell surface protein…”
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