Search Results - "Gagne, Stephane M"

Effect of pH on the Structure of the Recombinant C‑Terminal Domain of Nephila clavipes Dragline Silk Protein by Gauthier, Martin, Leclerc, Jérémie, Lefèvre, Thierry, Gagné, Stéphane M, Auger, Michèle

“…Spider silk proteins undergo a complex series of molecular events before being converted into an outstanding hierarchically organized fiber. Recent literature…”
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Structure, Dynamics, and Interaction of p54(nrb)/NonO RRM1 with 5' Splice Site RNA Sequence by Duvignaud, Jean-Baptiste, Bédard, Mikaël, Nagata, Takashi, Muto, Yutaka, Yokoyama, Shigeyuki, Gagné, Stéphane M, Vincent, Michel

“…p54(nrb)/NonO is a nuclear RNA-binding protein involved in many cellular events such as pre-mRNA processing, transcription, and nuclear retention of…”
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Hydrodynamical properties of recombinant spider silk proteins: Effects of pH, salts and shear, and implications for the spinning process by Leclerc, Jérémie, Lefèvre, Thierry, Gauthier, Martin, Gagné, Stéphane M., Auger, Michèle

“…We have investigated the effect of pH, salts and shear on the hydrodynamical diameter of recombinant major ampullate (MA) rMaSpI silk proteins in solution as a…”
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An alternative reaction for heme degradation catalyzed by the Escherichia coli O157:H7 ChuS protein: Release of hematinic acid, tripyrrole and Fe(III) by Ouellet, Yannick H., Ndiaye, Cheikh Tidiane, Gagné, Stéphane M., Sebilo, Anne, Suits, Michael D.L., Jubinville, Éric, Jia, Zongchao, Ivancich, Anabella, Couture, Manon

“…As part of the machinery to acquire, internalize and utilize heme as a source of iron from the host, some bacteria possess a canonical heme oxygenase, where…”
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Challenges with the Preparation of a Soluble and Active Form of LRAT by Roy, Sarah, Cantin, Line, Grondin, Jordan, Boulanger, Vincent, Gauthier, Marie-Eve, Gagne, Stephane M., Salesse, Christian

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Structure and Dynamics of Mycobacterium tuberculosis Truncated Hemoglobin N: Insights from NMR Spectroscopy and Molecular Dynamics Simulations by Savard, Pierre-Yves, Daigle, Richard, Morin, Sébastien, Sebilo, Anne, Meindre, Fanny, Lagüe, Patrick, Guertin, Michel, Gagné, Stéphane M

“…The potent nitric oxide dioxygenase (NOD) activity (trHbN–Fe2+–O2 + •NO → trHbN–Fe3+–OH2 + NO3 –) of Mycobacterium tuberculosis truncated hemoglobin N (trHbN)…”
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A Lactococcal Phage Protein Promotes Viral Propagation and Alters the Host Proteomic Response During Infection by Lemay, Marie-Laurence, Maaß, Sandra, Otto, Andreas, Hamel, Jérémie, Plante, Pier-Luc, Rousseau, Geneviève M, Tremblay, Denise M, Shi, Rong, Corbeil, Jacques, Gagné, Stéphane M, Becher, Dörte, Moineau, Sylvain

“…The lactococcal virulent phage p2 is a model for studying the genus, the most prevalent group of phages causing milk fermentation failures in cheese factories…”
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TEM-1 Backbone Dynamics—Insights from Combined Molecular Dynamics and Nuclear Magnetic Resonance by Fisette, Olivier, Morin, Sébastien, Savard, Pierre-Yves, Lagüe, Patrick, Gagné, Stéphane M.

“…Dynamic properties of class A β-lactamase TEM-1 are investigated from molecular dynamics (MD) simulations. Comparison of MD-derived order parameters with those…”
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Backbone Dynamics of TEM-1 Determined by NMR:  Evidence for a Highly Ordered Protein by Savard, Pierre-Yves, Gagné, Stéphane M

“…Backbone dynamics of TEM-1 β-lactamase (263 amino acids, 28.9 kDa) were studied by 15N nuclear magnetic resonance relaxation at 11.7, 14.1, and 18.8 T. The…”
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Conformation of Spider Silk Proteins In Situ in the Intact Major Ampullate Gland and in Solution by Lefèvre, Thierry, Leclerc, Jérémie, Rioux-Dubé, Jean-François, Buffeteau, Thierry, Paquin, Marie-Claude, Rousseau, Marie-Eve, Cloutier, Isabelle, Auger, Michèle, Gagné, Stéphane M, Boudreault, Simon, Cloutier, Conrad, Pézolet, Michel

“…To understand the spinning process of dragline silk by spiders, the protein conformation before spinning has to be determined. Raman confocal spectromicroscopy…”
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The Weak Enzymatic Activity of Truncated Lecithin Retinol Acyltransferase (LRAT) Mutants cannot be Explained by their Affinity for All-Trans Retinol by Roy, Sarah, Coutinho, Ana, Cantin, Line, Gauthier, Marie-Eve, Prieto, Manuel, Gagne, Stephane M., Salesse, Christian

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Structural and antimicrobial properties of human pre-elafin/trappin-2 and derived peptides against Pseudomonas aeruginosa by Bellemare, Audrey, Vernoux, Nathalie, Morin, Sébastien, Gagné, Stéphane M, Bourbonnais, Yves

“…Pre-elafin/trappin-2 is a human innate defense molecule initially described as a potent inhibitor of neutrophil elastase. The full-length protein as well as…”
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Implementing a web‐based introductory bioinformatics course for non‐bioinformaticians that incorporates practical exercises by Vincent, Antony T., Bourbonnais, Yves, Brouard, Jean‐Simon, Deveau, Hélène, Droit, Arnaud, Gagné, Stéphane M., Guertin, Michel, Lemieux, Claude, Rathier, Louis, Charette, Steve J., Lagüe, Patrick

“…A recent scientific discipline, bioinformatics, defined as using informatics for the study of biological problems, is now a requirement for the study of…”
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Simple tests for the validation of multiple field spin relaxation data by Morin, Sébastien, Gagné, Stéphane M

“…¹⁵N spin relaxation data is widely used to extract detailed dynamic information regarding bond vectors such as the amide N-H bond of the protein backbone…”
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Chimeric β-lactamases: global conservation of parental function and fast time-scale dynamics with increased slow motions by Clouthier, Christopher M, Morin, Sébastien, Gobeil, Sophie M C, Doucet, Nicolas, Blanchet, Jonathan, Nguyen, Elisabeth, Gagné, Stéphane M, Pelletier, Joelle N

“…Enzyme engineering has been facilitated by recombination of close homologues, followed by functional screening. In one such effort, chimeras of two class-A…”
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β-Helix structure and ice-binding properties of a hyperactive antifreeze protein from an insect by Kuiper, Michael J, Davies, Peter L, Gagné, Stéphane M, Graether, Steffen P, Jia, Zongchao, Sykes, Brian D, Walker, Virginia K

“…Insect antifreeze proteins (AFP) are considerably more active at inhibiting ice crystal growth than AFP from fish or plants. Several insect AFPs, also known as…”
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Structure and dynamics of the N-terminal half of hepatitis C virus core protein: An intrinsically unstructured protein by Duvignaud, Jean-Baptiste, Savard, Christian, Fromentin, Rémi, Majeau, Nathalie, Leclerc, Denis, Gagné, Stéphane M.

“…Hepatitis C virus core protein plays an important role in the assembly and packaging of the viral genome. We have studied the structure of the N-terminal half…”
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Structure and dynamics changes induced by 2,2,2-trifluoro-ethanol (TFE) on the N-terminal half of hepatitis C virus core protein by Duvignaud, Jean-Baptiste, Leclerc, Denis, Gagné, Stéphane M

“…The Core protein of hepatitis C virus is involved in several interactions other than the encapsidation of viral RNA. We recently proposed that this is related…”
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Structure and pH-induced alterations of recombinant and natural spider silk proteins in solution by Leclerc, Jérémie, Lefèvre, Thierry, Pottier, Fabien, Morency, Louis-Philippe, Lapointe-Verreault, Camille, Gagné, Stéphane M., Auger, Michèle

“…The spinning process of spiders can modulate the mechanical properties of their silk fibers. It is therefore of primary importance to understand what are the…”
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Interfering with hepatitis C virus assembly in vitro using affinity peptides directed towards core protein by Duvignaud, Jean-Baptiste, Majeau, Nathalie, Delisle, Priscilla, Voyer, Normand, Gagné, Stéphane M, Leclerc, Denis

“…Viral assembly is a crucial key step in the life cycle of every virus. In the case of Hepatitis C virus (HCV), the core protein is the only structural protein…”
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