Search Results - "Gagné, Sebastien"
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Ultrahigh‐performance liquid chromatography–tandem mass spectrometry quantitation of o‐cresol in hydrolyzed human urine to assess toluene exposure
Published in Rapid communications in mass spectrometry (30-08-2023)“…Rationale Toluene is a volatile organic compound used in domestic and industrial applications. The main routes of workplace exposure to toluene are inhalation…”
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Transconjunctival XEN45 Implantation for Glaucoma Performed at the Slit Lamp: A Pilot Study
Published in Journal of glaucoma (01-08-2022)“…This pilot study of ab externo implantation of a gel microstent is a novel, minimally invasive glaucoma surgery performed at the slit lamp that is effective…”
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3
A multiplexed cell assay in HepG2 cells for the identification of delta-5, delta-6, and delta-9 desaturase and elongase inhibitors
Published in Journal of biomolecular screening (01-02-2010)“…A multiplexed cell assay has been optimized to measure the activities of fatty acyl-CoA elongase, delta-5 desaturase (Delta5D), delta-6 desaturase (Delta6D),…”
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A validated UPLC-MS/MS method for the determination of aliphatic and aromatic isocyanate exposure in human urine
Published in Analytical and bioanalytical chemistry (2020)“…4,4′-Methylenediphenyldiisocyanate (MDI), toluenediisocyanate (2,4-TDI and 2,6-TDI), and 1,6′-hexamethylenediisocyanate (HDI) are all commonly used in the…”
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Achieving greater selectivity for the analysis of o-, m-, p-methylhippuric acids in workers’ urine by ultra performance liquid chromatography coupled with tandem mass spectrometry
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-07-2013)“…•A selective method for o-, m- and p-methylhippuric acid analysis has been developed.•Chromatographic separation has been optimized to resolve the three…”
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Prevalence, Progression, and Impact of Glaucoma on Vision After Boston Type 1 Keratoprosthesis Surgery
Published in American journal of ophthalmology (01-02-2012)“…Purpose To report glaucoma outcomes after Boston type 1 keratoprosthesis (KPro) surgery, in particular, glaucoma prevalence, progression, and treatment. Design…”
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Occupational health and safety, metal exposures and multi-exposures health risk in Canadian electronic waste recycling facilities
Published in Waste management (Elmsford) (15-06-2023)“…•Electronic recycling exposes workers to toxic metals, e.g. lead, cadmium and nickel.•Metals and dust concentrations are associated with the volume of…”
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Standardized Procedure for the Simultaneous Determination of the Matrix Effect, Recovery, Process Efficiency, and Internal Standard Association
Published in Analytical chemistry (Washington) (18-07-2017)“…The matrix effects (MEs) on the quantification of an analyte can be significant and should not be neglected during development and validation of an analytical…”
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Comprehensive methylene diphenyl diisocyanate (MDI) evaluation method comparison using a laboratory generation system
Published in Environmental science--processes & impacts (25-05-2023)“…Isocyanates are reactive semivolatile contaminants that must be assessed in occupational environments, and specific evaluation methods are required to address…”
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Surface contamination with nine antineoplastic drugs in 109 canadian centers; 10 years of a monitoring program
Published in Journal of oncology pharmacy practice (01-03-2022)“…Introduction Healthcare workers exposure to antineoplastic drugs can lead to adverse health effects. Guidelines promote the safe handling of antineoplastic…”
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11
Development of a method for quantification of toluene diisocyanate and methylenediphenyl diisocyanate migration from polyurethane foam sample surface to artificial sweat by HPLC-UV-MS
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-04-2020)“…•Migration test from US EPA for evaluating potential dermal exposure from home furniture.•Quantification of migration of MDI and TDI from flexible foam to…”
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Development of a Method for Preservation, Extraction, and Quantitation of 4,4'-Methylenedianiline in Soils of Varied Texture and Organic Matter Content
Published in Communications in Soil Science and Plant Analysis (12-04-2023)“…Despite the reactivity and degradability of 4,4'-methylenedianiline (4,4'-MDA) with organic matter in soils, the improvement of Brunet et al. method makes it…”
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Cross-sectional evaluation of surface contamination with 9 antineoplastic drugs in 93 Canadian healthcare centers: 2019 results
Published in Journal of oncology pharmacy practice (01-12-2020)“…Introduction The primary objective was to describe environmental contamination with National Institute for Occupational Safety and Health Group 1 hazardous…”
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14
Determination of triglycidyl isocyanurate from air samples by ultra-performance liquid chromatography coupled with coordination ion spray mass spectrometry
Published in Rapid communications in mass spectrometry (30-05-2015)“…Rationale Ultra‐performance liquid chromatography (UPLC) coupled with coordination ion spray tandem mass spectrometry was used for the analysis of air samples…”
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A reliable method by ultra-performance liquid chromatography coupled with tandem mass spectrometry to quantify and confirm simultaneously the presence of solvent metabolites in workers' urine
Published in Rapid communications in mass spectrometry (15-04-2012)“…Ultra‐performance liquid chromatography coupled with tandem mass spectrometry was used for the biological monitoring of workers occupationally exposed to…”
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A validated liquid chromatography/tandem mass spectrometry method for 4,4′‐methylenedianiline quantitation in human urine as a measure of 4,4′‐methylene diphenyl diisocyanate exposure
Published in Rapid communications in mass spectrometry (30-03-2019)“…Rationale 4,4′‐Methylene diphenyl diisocyanate (MDI) is a highly reactive isocyanate used in the production of polyurethanes. Workers exposed to these products…”
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Development of a new SPE UPLC–MS/MS method for extraction and quantitation of toluene diamine on gloves following toluene diisocyanate exposure
Published in Rapid communications in mass spectrometry (30-08-2022)“…Rationale Toluene diisocyanate (TDI) is a highly reactive isocyanate commonly used as a mixture of 2,4‐ and 2,6‐ isomers in the production of flexible foams…”
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Determination of trans,trans-muconic acid in workers' urine through ultra-performance liquid chromatography coupled to tandem mass spectrometry
Published in Biomedical chromatography (01-05-2013)“…ABSTRACT A novel method for the biological monitoring of benzene‐exposed workers has been developed through ultra‐performance liquid chromatography coupled to…”
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24-Month Phase I/II Clinical Trial of Bimatoprost Sustained-Release Implant (Bimatoprost SR) in Glaucoma Patients
Published in Drugs (New York, N.Y.) (01-02-2020)“…Objective The objective of this study was to evaluate the safety and intraocular pressure (IOP)-lowering effects over 24 months of biodegradable bimatoprost…”
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Comprehensive Proteomics Approach in Characterizing and Quantifying Allergenic Proteins from Northern Shrimp: Toward Better Occupational Asthma Prevention
Published in Journal of proteome research (01-02-2013)“…Occupational asthma is a major chronic health dilemma among workers involved in the seafood industry. Several proteins notoriously known to cause asthma have…”
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