Search Results - "Gaggeri, Raffaella"

Development and validation of an HPLC-DAD method for the simultaneous identification and quantification of Topotecan, Irinotecan, Etoposide, Doxorubicin and Epirubicin by Sanogo, Seydou, Silimbani, Paolo, Gaggeri, Raffaella, Masini, Carla

“…[Display omitted] The knowledge of the chemical stability of drugs prepared and administered in hospital is of paramount importance for establishing the…”
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Quick development of an analytical enantioselective high performance liquid chromatography separation and preparative scale-up for the flavonoid Naringenin by Gaggeri, Raffaella, Rossi, Daniela, Collina, Simona, Mannucci, Barbara, Baierl, Marcel, Juza, Markus

“…The HPLC enantioselective separation of ( R/ S)-Naringenin, a chiral flavonoid found in several fruits juices and well-known for its beneficial health-related…”
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TNF-α blocker effect of naringenin-loaded sericin microparticles that are potentially useful in the treatment of psoriasis by Chlapanidas, Theodora, Perteghella, Sara, Leoni, Flavio, Faragò, Silvio, Marazzi, Mario, Rossi, Daniela, Martino, Emanuela, Gaggeri, Raffaella, Collina, Simona

“…This study aims to evaluate the effect of combined use of the racemic flavanone Naringenin (NRG) and the protein sericin as TNF-α blockers. Sericin (SMs) and…”
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Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016) by Collina, Simona, Bignardi, Emanuele, Rui, Marta, Rossi, Daniela, Gaggeri, Raffaella, Zamagni, Alice, Cortesi, Michela, Tesei, Anna

“…Although several molecular targets against cancer have been identified, there is a continuous need for new therapeutic strategies. Sigma Receptors (SRs)…”
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PROTECT Trial: A cluster-randomized study with hydroxychloroquine versus observational support for prevention or early-phase treatment of Coronavirus disease (COVID-19): A structured summary of a study protocol for a randomized controlled trial by Nanni, Oriana, Viale, Pierluigi, Vertogen, Bernadette, Lilli, Claudia, Zingaretti, Chiara, Donati, Caterina, Masini, Carla, Monti, Manuela, Serra, Patrizia, Vespignani, Roberto, Grossi, Veruska, Biggeri, Annibale, Scarpi, Emanuela, Galardi, Francesca, Bertoni, Lucia, Colamartini, Americo, Falcini, Fabio, Altini, Mattia, Massa, Ilaria, Gaggeri, Raffaella, Martinelli, Giovanni

“…Hydroxychloroquine has shown to have antiviral activity in vitro against coronaviruses, specifically SARS-CoV-2. It is believed to block virus infection by…”
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Chiral flavanones from Amygdalus lycioides Spach: structural elucidation and identification of TNFalpha inhibitors by bioactivity-guided fractionation by Gaggeri, Raffaella, Rossi, Daniela, Christodoulou, Michael S, Passarella, Daniele, Leoni, Flavio, Azzolina, Ornella, Collina, Simona

“…Phytochemical investigation on the Amygdalus lycioides Spach branchelets resulted in the isolation of four chiral flavanones: (2R,3R)-Taxifolin,…”
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Chemical, Pharmacological, and in vitro Metabolic Stability Studies on Enantiomerically Pure RC-33 Compounds: Promising Neuroprotective Agents Acting as σ1 Receptor Agonists by Rossi, Daniela, Pedrali, Alice, Gaggeri, Raffaella, Marra, Annamaria, Pignataro, Luca, Laurini, Erik, Dal Col, Valentina, Fermeglia, Maurizio, Pricl, Sabrina, Schepmann, Dirk, Wünsch, Bernhard, Peviani, Marco, Curti, Daniela, Collina, Simona

“…Our recent research efforts identified racemic RC‐33 as a potent and metabolically stable σ1 receptor agonist. Herein we describe the isolation of pure RC‐33…”
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Influence of the extraction mode on the yield of hyperoside, vitexin and vitexin-2''-O-rhamnoside from Crataegus monogyna Jacq. (hawthorn) by Martino, Emanuela, Collina, Simona, Rossi, Daniela, Bazzoni, Deborah, Gaggeri, Raffaella, Bracco, Francesco, Azzolina, Ornella

“…Introduction - The extract of Crataegus monogyna shows sedative, hypotensive, vasodilator and cardio-tonic actions. Although several papers dealing with the…”
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Transhepatic Arterial Chemoembolization with Oxaliplatin-eluting Microspheres (OEM-TACE) for Unresectable Hepatic Tumors by POGGI, Guido, QUARETTI, Pietro, MONTAGNA, Michela, AMATU, Alessio, TERAGNI, Cristina, PALUMBO, Ilaria, TRAVERSO, Elena, TONINI, Stefano, VILLANI, Laura, SCELSI, Mario, BAIARDI, Paola, GRAZIA FELISI, Maria, MINOIA, Claudio, SOTTOTETTI, Federico, TAGLIAFERRI, Barbara, RICCARDI, Alberto, BERNARDO, Giovanni, REGAZZI BONORA, Mario, GAGGERI, Raffaella, RONCHI, Anna, MASSA SALUZZO, Cesare, AZZARETTI, Andrea, RODOLICO, Giuseppe

“…Background: While conventional transhepatic arterial chemoembolization (TACE) is accepted worldwide as an effective treatment for patients with unresectable…”
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Simultaneous determination of gemcitabine, taxol, cyclophosphamide and ifosfamide in wipe samples by high-performance liquid chromatography/tandem mass spectrometry: protocol of validation and uncertainty of measurement by Sottani, Cristina, Turci, Roberta, Schierl, Rudolf, Gaggeri, Raffaella, Barbieri, Anna, Violante, Francesco Saverio, Minoia, Claudio

“…Measurable levels of anticancer agents are still detected on work surfaces in health‐care settings. However, application of recent guidelines for the…”
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Identification of a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells by Rossi, Daniela, Pedrali, Alice, Urbano, Mariangela, Gaggeri, Raffaella, Serra, Massimo, Fernández, Leyden, Fernández, Michael, Caballero, Julio, Ronsisvalle, Simone, Prezzavento, Orazio, Schepmann, Dirk, Wuensch, Bernhard, Peviani, Marco, Curti, Daniela, Azzolina, Ornella, Collina, Simona

“…Herein we report the synthesis, drug-likeness evaluation, and in vitro studies of new sigma (σ) ligands based on arylalkenylaminic scaffold. For the most…”
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Stability of calcium levofolinate reconstituted in syringes and diluted in NaCl 0.9% and glucose 5% polyolefin/polyamide infusion bags by Sanogo, Seydou, Silimbani, Paolo, Gaggeri, Raffaella, Masini, Carla

“…Purpose Calcium levofolinate (CaLev) for intravenous administration is commercially available as a powder that must be reconstituted for injection or…”
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Sigma receptor modulators: a patent review by Collina, Simona, Gaggeri, Raffaella, Marra, Annamaria, Bassi, Andrea, Negrinotti, Sara, Negri, Francesca, Rossi, Daniela

“…Sigma receptors are involved in several central nervous system (CNS) disorders, including mood disorders (depression and anxiety), psychosis, schizophrenia,…”
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(R)-(-)-Aloesaponol III 8-Methyl Ether from Eremurus persicus: A Novel Compound against Leishmaniosis by Rossi, Daniela, Ahmed, Karzan Mahmood, Gaggeri, Raffaella, Della Volpe, Serena, Maggi, Lauretta, Mazzeo, Giuseppe, Longhi, Giovanna, Abbate, Sergio, Corana, Federica, Martino, Emanuela, Machado, Marisa, Varandas, Raquel, Sousa, Maria do Céu, Collina, Simona

“…Leishmaniosis is a neglected tropical disease which affects several millions of people worldwide. The current drug therapies are expensive and often lack…”
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Validation of RP-HPLC method to assess the compatibility of metoclopramide and midazolam intravenous mixture used in patients with cancer by Sanogo, Seydou, Silimbani, Paolo, Gaggeri, Raffaella, Rossi, Romina, Elviri, Lisa, Maltoni, Marco, Masini, Carla

“…BackgroundThe delivery of intravenous medication by continuous infusion is necessary and widespread for treatment of patients with advanced cancer. Few…”
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An Eco-Friendly Enantioselective Access to (R)-Naringenin as Inhibitor of Proinflammatory Cytokine Release by Gaggeri, Raffaella, Rossi, Daniela, Daglia, Maria, Leoni, Flavio, Avanzini, Maria Antonia, Mantelli, Melissa, Juza, Markus, Collina, Simona

“…(RS)‐Naringenin is a flavanone well‐known for its beneficial health‐related properties, such as its anti‐inflammatory activity. The preparative…”
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Identification of Peptides with ELAV-like mRNA-Stabilizing Effect: An Integrated In Vitro/In Silico Approach by Amadio, Marialaura, Pascale, Alessia, Govoni, Stefano, Laurini, Erik, Pricl, Sabrina, Gaggeri, Raffaella, Rossi, Daniela, Collina, Simona

“…Embryonic lethal abnormal vision (ELAV) proteins are RNA‐binding proteins that bind specific adenine and uridine‐rich elements mainly located in the…”
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TNF-[alpha] Blocker Effect of Naringenin-Loaded Sericin Microparticles that Are Potentially Useful in the Treatment of Psoriasis by Chlapanidas, Theodora, Perteghella, Sara, Leoni, Flavio, Faragò, Silvio, Marazzi, Mario, Rossi, Daniela, Martino, Emanuela, Gaggeri, Raffaella, Collina, Simona

“…This study aims to evaluate the effect of combined use of the racemic flavanone Naringenin (NRG) and the protein sericin as TNF-α blockers. Sericin (SMs) and…”
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Formulation of microspheres containing Crataegus monogyna Jacq. extract with free radical scavenging activity by Lucconi, Giulia, Chlapanidas, Theodora, Martino, Emanuela, Gaggeri, Raffaella, Perteghella, Sara, Rossi, Daniela, Faragò, Silvio, Vigo, Daniele, Faustini, Massimo, Collina, Simona, Torre, Maria Luisa

“…Abstract Extracts of Crataegus monogyna Jacq. (hawthorn) show an interesting free radical scavenging (FRS) effect, related to their flavonoids content…”
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Chemical, Pharmacological, and in vitro Metabolic Stability Studies on Enantiomerically Pure RC-33 Compounds: Promising Neuroprotective Agents Acting as [sigma]1 Receptor Agonists by Rossi, Daniela, Pedrali, Alice, Gaggeri, Raffaella, Marra, Annamaria, Pignataro, Luca, Laurini, Erik, DalCol, Valentina, Fermeglia, Maurizio, Pricl, Sabrina, Schepmann, Dirk, Wunsch, Bernhard, Peviani, Marco, Curti, Daniela, Collina, Simona

“…Our recent research efforts identified racemic RC-33 as a potent and metabolically stable σ1 receptor agonist. Herein we describe the isolation of pure RC-33…”
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