Search Results - "Gage, M."
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1
FFAR4: A New Player in Cardiometabolic Disease?
Published in Endocrinology (Philadelphia) (01-08-2021)“…Free fatty acids (FFAs) are implicated in the pathogenesis of metabolic diseases that includes obesity, type 2 diabetes mellitus, and cardiovascular disease…”
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2
Improving Surgical Site Infections: Using National Surgical Quality Improvement Program Data to Institute Surgical Care Improvement Project Protocols in Improving Surgical Outcomes
Published in Journal of the American College of Surgeons (01-05-2010)“…Background The National Surgical Quality Improvement Program (NSQIP) began with the Veterans Affairs system to reduce morbidity and mortality by evaluating…”
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3
Novel Roles of FFAR4 in Macrophage Foam Cell Formation
Published in The FASEB journal (01-05-2022)“…Free fatty acid receptor 4 (FFAR4), also known as G‐protein coupled receptor 120 (GPR120), is a long‐chain unsaturated fatty acid receptor expressed in…”
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4
Experimental evolution reveals that males evolving within warmer thermal regimes improve reproductive performance under heatwave conditions in a model insect
Published in Journal of evolutionary biology (02-11-2024)“…Climate change is increasing mean temperatures, and intensifying heatwaves. Natural populations may respond to stress through shorter-term acclimation via…”
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Facultative polyandry protects females from compromised male fertility caused by heatwave conditions
Published in Animal behaviour (01-08-2021)“…Why is polyandry such a common mating behaviour when it exposes females to a range of significant fitness costs? Here, we investigated whether polyandry…”
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Social support coping styles and psychological distress during the COVID-19 pandemic: The moderating role of sex
Published in Journal of affective disorders (01-07-2022)“…The coronavirus disease 2019 (COVID-19) pandemic led to the onset and exacerbation of mental health problems, such as stress, anxiety, and depression; yet…”
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7
Insertional Achilles Tendinopathy
Published in Clinics in podiatric medicine and surgery (01-04-2017)“…Posterior heel pain is a common condition of the foot and ankle and is seen in a variety of foot types. Nonoperative treatment methods consisting of shoes…”
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Disrupting LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation
Published in Proceedings of the National Academy of Sciences - PNAS (10-07-2018)“…Macrophages are key immune cells for the initiation and development of atherosclerotic lesions. However, the macrophage regulatory nodes that determine how…”
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9
Translational advances regarding hereditary breast cancer syndromes
Published in Journal of surgical oncology (01-04-2012)“…Approximately 5–10% of breast cancers may be inheritable, up to 90% of which are due to mutations in BRCA1 and BRCA2. A substantial minority are caused by…”
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10
Effects of Chronic Pain Diagnoses on the Antidepressant Efficacy of Transcranial Magnetic Stimulation
Published in Psychosomatic medicine (01-07-2024)“…Major depressive disorder (MDD) and chronic pain are highly comorbid and bidirectionally related. Repetitive transcranial magnetic stimulation (rTMS) over the…”
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Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge
Published in PloS one (02-11-2023)“…The murine Bordetella pertussis challenge model has been utilized in preclinical research for decades. Currently, inconsistent methodologies are employed by…”
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Pharmacokinetic evaluation of ibrexafungerp for the treatment of vulvovaginal candidiasis and beyond
Published in Expert opinion on drug metabolism & toxicology (02-08-2024)“…Ibrexafungerp is a new triterpenoid antifungal agent with activity against a variety of fungal species, including spp. and echinocandin-resistant spp. This…”
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13
Sarcomas in the United States: Recent trends and a call for improved staging
Published in Oncotarget (29-03-2019)“…Sarcomas represent a heterogeneous group of tumors, and there is lack of data describing contemporary changes in patterns of care. We evaluated the…”
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14
A comprehensive analysis of the role of native and modified HDL in ER stress in primary macrophages
Published in Frontiers in cardiovascular medicine (12-09-2024)“…Recent findings demonstrate that high density lipoprotein (HDL) function rather than HDL-cholesterol levels themselves may be a better indicator of…”
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The role of threat appraisal and coping style in psychological response to the COVID-19 pandemic among university students
Published in Journal of affective disorders reports (01-04-2022)“…•Lower levels of avoidant coping were associated with less distress.•High levels of threat appraisal were associated with more distress.•Emotion-focused coping…”
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Immunization with an mRNA DTP vaccine protects against pertussis in rats
Published in Infection and immunity (13-08-2024)“…is a Gram-negative bacterium that is the causative agent of the respiratory disease known as pertussis. Since the switch to the acellular vaccines of DTaP and…”
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Virus-like particles displaying the mature C-terminal domain of filamentous hemagglutinin are immunogenic and protective against Bordetella pertussis respiratory infection in mice
Published in Infection and immunity (13-08-2024)“…the bacterium responsible for whooping cough, remains a significant public health challenge despite the existing licensed pertussis vaccines. Current acellular…”
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BECC438b TLR4 agonist supports unique immune response profiles from nasal and muscular DTaP pertussis vaccines in murine challenge models
Published in Infection and immunity (12-03-2024)“…The protection afforded by acellular pertussis vaccines wanes over time, and there is a need to develop improved vaccine formulations. Options to improve the…”
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19
Disrupting LXRa phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation
Published in Proceedings of the National Academy of Sciences - PNAS (10-07-2018)“…Macrophages are key immune cells for the initiation and development of atherosclerotic lesions. However, the macrophage regulatory nodes that determine how…”
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20
Molecular Network Reinforcement of Sol-Gel Glasses
Published in Advanced materials (Weinheim) (19-11-2007)“…Mechanical properties of organic/ inorganic thin‐films prepared from bridged silicon precursors have been investigated. The Young's modulus follows a linear…”
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