Search Results - "Gage, James"

Distal Femoral Extension Osteotomy and Patellar Tendon Advancement to Treat Persistent Crouch Gait in Cerebral Palsy by Stout, Jean L, Gage, James R, Schwartz, Michael H, Novacheck, Tom F

“…BackgroundHallmarks of a persistent crouched walking pattern exhibited by individuals with cerebral palsy usually include loss of an adequate plantar…”
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A General Protocol for Addressing Speciation of the Active Catalyst Applied to Ligand-Accelerated Enantioselective C(sp3)–H Bond Arylation by Hill, David E, Pei, Qing-lan, Zhang, En-xuan, Gage, James R, Yu, Jin-Quan, Blackmond, Donna G

“…The potential role of dimeric catalyst species on or off the catalytic cycle is considered for a case of Pd-catalyzed C–H functionalization, leading to the…”
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Commercial-Scale Visible Light Trifluoromethylation of 2‑Chlorothiophenol Using CF3I Gas by Harper, Kaid C, Zhang, En-Xuan, Liu, Zhi-Qing, Grieme, Timothy, Towne, Timothy B, Mack, Daniel J, Griffin, Jeremy, Zheng, Song-Yuan, Zhang, Ning-Ning, Gangula, Srinivas, Yuan, Jia-Long, Miller, Robert, Huang, Ping-Zhong, Gage, James, Diwan, Moiz, Ku, Yi-Yin

“…Despite the growth of photoredox methods in academia, application of photoredox at scale in the pharmaceutical and fine chemical industries has been slow. In…”
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Distal Femoral Extension Osteotomy and Patellar Tendon Advancement to Treat Persistent Crouch Gait in Cerebral Palsy: Surgical Technique by Novacheck, Tom F, Stout, Jean L, Gage, James R, Schwartz, Michael H

“…BACKGROUNDHallmarks of a persistent crouched walking pattern exhibited by individuals with cerebral palsy usually include loss of an adequate plantar…”
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High Output Continuous Nitration by Gage, James R, Guo, Xiaowen, Tao, Jian, Zheng, Changsheng

“…The design and use of a flow reactor for scaling up an exothermic nitration reaction in a safe manner on production scale is described. The flow reactor is…”
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The PMI Predictor app to enable green-by-design chemical synthesis by Borovika, Alina, Albrecht, Jacob, Li, Jun, Wells, Andrew S., Briddell, Christiana, Dillon, Barry R., Diorazio, Louis J., Gage, James R., Gallou, Fabrice, Koenig, Stefan G., Kopach, Michael E., Leahy, David K., Martinez, Isamir, Olbrich, Martin, Piper, Jared L., Roschangar, Frank, Sherer, Edward C., Eastgate, Martin D.

“…The development of sustainable processes for the synthesis of new clinical candidates is a priority for every pharmaceutical company. The ultimate efficiency…”
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Kinematic and kinetic factors that correlate with improved knee flexion following treatment for stiff-knee gait by Goldberg, Saryn R., Õunpuu, Sylvia, Arnold, Allison S., Gage, James R., Delp, Scott L.

“…Stiff-knee gait is a movement abnormality in which knee flexion during swing phase is significantly diminished. This study investigates the relationships…”
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Orthopedic management of spasticity in cerebral palsy by Novacheck, Tom F, Gage, James R

“…This article summarizes our experience with cerebral palsy. The primary and secondary deformities that occur with cerebral palsy are described, followed by a…”
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Is simultaneous hamstring lengthening necessary when performing distal femoral extension osteotomy and patellar tendon advancement? by Healy, Michael T, Schwartz, Michael H, Stout, Jean L, Gage, James R, Novacheck, Tom F

“…Abstract Crouch gait is common in individuals with cerebral palsy. Recently published data has shown that distal femoral extension osteotomy with patellar…”
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An Update on the Treatment of Gait Problems in Cerebral Palsy by Gage, James R, Novacheck, Tom F

“…This article summarizes our experience with cerebral palsy over the past 20 years. The primary and secondary deformities that occur with cerebral palsy are…”
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An Update on the Treatment of Gait Problems in Cerebral Palsy by Gage, James R, Novacheck, Tom F

“…This article summarizes our experience with cerebral palsy over the past 20 years. The primary and secondary deformities that occur with cerebral palsy are…”
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Con: Interobserver Variability of Gait Analysis by Gage, James R

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Novel oxazolidinone–quinolone hybrid antimicrobials by Gordeev, Mikhail F., Hackbarth, Corinne, Barbachyn, Michael R., Banitt, Lee S., Gage, James R., Luehr, Gary W., Gomez, Marcela, Trias, Joaquim, Morin, Sara E., Zurenko, Gary E., Parker, Christian N., Evans, Jonathan M., White, Richard J., Patel, Dinesh V.

“…Antimicrobial compounds incorporating oxazolidinone and quinolone pharmacophore substructures have been synthesized and evaluated. Representative analogues 2,…”
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Total synthesis of (+)-calyculin A by Evans, David A, Gage, James R, Leighton, James L

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Asymmetric synthesis of calyculin A. 2. The C26-C37 .gamma.-amino acid fragments by Evans, David A, Gage, James R, Leighton, James L, Kim, Annette S

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Iodination and Metal Halogen Exchange of Aromatic Compounds:  An Improved Preparation of a Key Oxazolidinone Antibiotic Intermediate by Herrinton, Paul M, Owen, Carolyn E, Gage, James R

“…A new method for the preparation of a key intermediate for oxazolidinone antibiotic analogues is discussed. We have found that iodine−magnesium exchange can be…”
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Lengths of hamstrings and psoas muscles during crouch gait: effects of femoral anteversion by Schutte, L M, Hayden, S W, Gage, J R

“…Recent studies of muscle lengths measured by means of gait analysis data and musculoskeletal models have suggested that in many cases of crouch gait in…”
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A Convergent, Scalable Synthesis of HIV Protease Inhibitor PNU-140690 by Fors, Kristina S, Gage, James R, Heier, Richard F, Kelly, Robert C, Perrault, William R, Wicnienski, Nancy

“…PNU-140690, an inhibitor of the HIV protease enzyme undergoing clinical evalution as a chemotherapeutic agent for treatment of AIDS, was synthesized by a…”
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Semicontinuous Process for GMP Manufacture of a Carbapenem Intermediate via Carbene Insertion Using an Immobilized Rhodium Catalyst by Gage, James R., Chen, Furong, Dong, Changming, Gonzalez, Miguel A., Jiang, Yong, Luo, Yong, McLaws, Mark D., Tao, Jian

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Stereodivergent synthesis of sulfoxide-containing oxazolidinone antibiotics by Gage, James R, Perrault, William R, Poel, Toni-Jo, Thomas, Richard C

“…Carbamate 5 was prepared under mild conditions via a novel metal–halogen exchange procedure without competing benzyne formation. Selection of an appropriate…”
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