Search Results - "Gage, F."

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics‐Guided Warfarin Dosing: 2017 Update by Johnson, JA, Caudle, KE, Gong, L, Whirl‐Carrillo, M, Stein, CM, Scott, SA, Lee, MT, Gage, BF, Kimmel, SE, Perera, MA, Anderson, JL, Pirmohamed, M, Klein, TE, Limdi, NA, Cavallari, LH, Wadelius, M

“…This document is an update to the 2011 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2C9 and VKORC1 genotypes and warfarin…”
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Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation by Clelland, C.D, Choi, M, Romberg, C, Clemenson, G.D. Jr, Fragniere, A, Tyers, P, Jessberger, S, Saksida, L.M, Barker, R.A, Gage, F.H, Bussey, T.J

“…The dentate gyrus (DG) of the mammalian hippocampus is hypothesized to mediate pattern separation--the formation of distinct and orthogonal representations of…”
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Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients’ responsiveness to lithium by Stern, S, Santos, R, Marchetto, M C, Mendes, A P D, Rouleau, G A, Biesmans, S, Wang, Q-W, Yao, J, Charnay, P, Bang, A G, Alda, M, Gage, F H

“…Bipolar disorder (BD) is a progressive psychiatric disorder with more than 3% prevalence worldwide. Affected individuals experience recurrent episodes of…”
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Cost-Effectiveness of Dabigatran for Stroke Prophylaxis in Atrial Fibrillation by SHAH, Shimoli V, GAGE, Brian F

“…Recent studies have investigated alternatives to warfarin for stroke prophylaxis in patients with atrial fibrillation (AF), but whether these alternatives are…”
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Modeling psychiatric disorders at the cellular and network levels by Brennand, K J, Simone, A, Tran, N, Gage, F H

“…Although psychiatric disorders such as autism spectrum disorders, schizophrenia and bipolar disorder affect a number of brain regions and produce a complex…”
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Altered proliferation and networks in neural cells derived from idiopathic autistic individuals by Marchetto, M C, Belinson, H, Tian, Y, Freitas, B C, Fu, C, Vadodaria, K C, Beltrao-Braga, P C, Trujillo, C A, Mendes, A P D, Padmanabhan, K, Nunez, Y, Ou, J, Ghosh, H, Wright, R, Brennand, K J, Pierce, K, Eichenfield, L, Pramparo, T, Eyler, L T, Barnes, C C, Courchesne, E, Geschwind, D H, Gage, F H, Wynshaw-Boris, A, Muotri, A R

“…Autism spectrum disorders (ASD) are common, complex and heterogeneous neurodevelopmental disorders. Cellular and molecular mechanisms responsible for ASD…”
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Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise by Valdez, Gregorio, Tapia, Juan C., Kang, Hyuno, Clemenson, Gregory D., Gage, F. H., Lichtman, Jeff W., Sanes, Joshua R., Fischbach, Gerald D.

“…The cellular basis of age-related behavioral decline remains obscure but alterations in synapses are likely candidates. Accordingly, the beneficial effects on…”
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Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing by Johnson, J A, Gong, L, Whirl‐Carrillo, M, Gage, B F, Scott, S A, Stein, C M, Anderson, J L, Kimmel, S E, Lee, M T M, Pirmohamed, M, Wadelius, M, Klein, T E, Altman, R B

“…Warfarin is a widely used anticoagulant with a narrow therapeutic index and large interpatient variability in the dose required to achieve target…”
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Use of Pharmacogenetic and Clinical Factors to Predict the Therapeutic Dose of Warfarin by Gage, BF, Eby, C, Johnson, JA, Deych, E, Rieder, MJ, Ridker, PM, Milligan, PE, Grice, G, Lenzini, P, Rettie, AE, Aquilante, CL, Grosso, L, Marsh, S, Langaee, T, Farnett, LE, Voora, D, Veenstra, DL, Glynn, RJ, Barrett, A, McLeod, HL

“…Initiation of warfarin therapy using trial‐and‐error dosing is problematic. Our goal was to develop and validate a pharmacogenetic algorithm. In the derivation…”
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Predicting venous thromboembolism in multiple myeloma: development and validation of the IMPEDE VTE score by Sanfilippo, Kristen M., Luo, Suhong, Wang, Tzu‐Fei, Fiala, Mark, Schoen, Martin, Wildes, Tanya M., Mikhael, Joseph, Kuderer, Nicole M., Calverley, David C., Keller, Jesse, Thomas, Theodore, Carson, Kenneth R., Gage, Brian F.

“…Venous thromboembolism (VTE) is a common cause of morbidity and mortality among patients with multiple myeloma (MM). The International Myeloma Working Group…”
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Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia by Brennand, K, Savas, J N, Kim, Y, Tran, N, Simone, A, Hashimoto-Torii, K, Beaumont, K G, Kim, H J, Topol, A, Ladran, I, Abdelrahim, M, Matikainen-Ankney, B, Chao, S-h, Mrksich, M, Rakic, P, Fang, G, Zhang, B, Yates, J R, Gage, F H

“…Consistent with recent reports indicating that neurons differentiated in vitro from human-induced pluripotent stem cells (hiPSCs) are immature relative to…”
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Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male sprague–dawley rats in vivo by Farmer, J, Zhao, X, van Praag, H, Wodtke, K, Gage, F.H, Christie, B.R

“…We have previously shown that voluntary exercise produces enhanced neurogenesis and long-term potentiation (LTP) in the dentate gyrus (DG) of mice in vitro. In…”
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Generation of functional human serotonergic neurons from fibroblasts by Vadodaria, K C, Mertens, J, Paquola, A, Bardy, C, Li, X, Jappelli, R, Fung, L, Marchetto, M C, Hamm, M, Gorris, M, Koch, P, Gage, F H

“…The brain’s serotonergic system centrally regulates several physiological processes and its dysfunction has been implicated in the pathophysiology of several…”
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Clinical classification schemes for predicting hemorrhage: Results from the National Registry of Atrial Fibrillation (NRAF) by Gage, Brian F., Yan, Yan, Milligan, Paul E., Waterman, Amy D., Culverhouse, Robert, Rich, Michael W., Radford, Martha J.

“…Although warfarin and other anticoagulants can prevent ischemic events, they can cause hemorrhage. Quantifying the rate of hemorrhage is crucial for…”
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Characterizing Prenatal Maternal Distress With Unique Prenatal Cortisol Trajectories by Peterson, Gage F, Espel, Emma V, Davis, Elysia Poggi, Sandman, Curt A, Glynn, Laura M

“…Objective: It is widely assumed that glucocorticoids represent a primary mechanism through which exposure to adversity and maternal psychological distress…”
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What Students Value Most: A Qualitative Examination of Learner Experiences in a Fully Online Degree Program by Pham, Lam D., Matthews, Gage F., Cravens, Xiu

“…Background: Enrollment in online degree programs has grown rapidly in U.S. higher education institutions, but much of the research on online learning draws…”
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An in vitro model of lissencephaly: expanding the role of DCX during neurogenesis by Shahsavani, M, Pronk, R J, Falk, R, Lam, M, Moslem, M, Linker, S B, Salma, J, Day, K, Schuster, J, Anderlid, B-M, Dahl, N, Gage, F H, Falk, A

“…Lissencephaly comprises a spectrum of brain malformations due to impaired neuronal migration in the developing cerebral cortex. Classical lissencephaly is…”
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Accuracy of ICD-9-CM Codes for Identifying Cardiovascular and Stroke Risk Factors by Birman-Deych, Elena, Waterman, Amy D., Yan, Yan, Nilasena, David S., Radford, Martha J., Gage, Brian F.

“…Objectives: We sought to determine which ICD-9-CM codes in Medicare Part A data identify cardiovascular and stroke risk factors. Design and Participants: This…”
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Safety and efficacy of new anticoagulants for the prevention of venous thromboembolism after hip and knee arthroplasty: a meta-analysis by Venker, Brett, PharmD, Ganti, Beejal R., PharmD, Lin, Hannah, BA, Lee, Elizabeth D., MMS, PA-C, Nunley, Ryan M., MD, Gage, Brian F., MD, MSc

“…Abstract Background Venous thromboembolism (VTE) is a common and potentially fatal complication of arthroplasty. Methods We reviewed randomized trials to…”
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Adult brain neurogenesis and psychiatry : a novel theory of depression by JACOBS, B. L, VAN PRAAG, H, GAGE, F. H

“…Neurogenesis (the birth of new neurons) continues postnatally and into adulthood in the brains of many animal species, including humans. This is particularly…”
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