Search Results - "Gaete, S."

ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels by Narahari, Adishesh K, Kreutzberger, Alex Jb, Gaete, Pablo S, Chiu, Yu-Hsin, Leonhardt, Susan A, Medina, Christopher B, Jin, Xueyao, Oleniacz, Patrycja W, Kiessling, Volker, Barrett, Paula Q, Ravichandran, Kodi S, Yeager, Mark, Contreras, Jorge E, Tamm, Lukas K, Bayliss, Douglas A

“…Pannexin 1 (Panx1) is a membrane channel implicated in numerous physiological and pathophysiological processes via its ability to support release of ATP and…”
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Taking a close look at a large-pore channel by Gaete, Pablo S, Contreras, Jorge E

“…The structure of pannexin 1, a channel protein with a large pore, has been determined for the first time…”
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Two Toxoplasma gondii putative pore-forming proteins, GRA47 and GRA72, influence small molecule permeability of the parasitophorous vacuole by Bitew, Mebratu A, Gaete, Pablo S, Swale, Christopher, Maru, Parag, Contreras, Jorge E, Saeij, Jeroen P J

“…, a medically important intracellular parasite, uses GRA proteins secreted from dense granule organelles to mediate nutrient flux across the parasitophorous…”
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Connexin and Pannexin Large-Pore Channels in Microcirculation and Neurovascular Coupling Function by Burboa, Pía C., Puebla, Mariela, Gaete, Pablo S., Durán, Walter N., Lillo, Mauricio A.

“…Microcirculation homeostasis depends on several channels permeable to ions and/or small molecules that facilitate the regulation of the vasomotor tone,…”
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Function of P2X4 Receptors Is Directly Modulated by a 1:1 Stoichiometric Interaction With 5-HT3A Receptors by Soto, Paola, Gaete, Pablo S., Fuentes, Christian, Lozano, Benjamin, Naulin, Pamela A., Figueroa, Xavier F., Barrera, Nelson Patricio

“…Interacting receptors at the neuronal plasma membrane represent an additional regulatory mode for intracellular transduction pathways. P2X4 receptor triggers…”
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Functional Role of Connexins and Pannexins in the Interaction Between Vascular and Nervous System by Gaete, Pablo S., Lillo, Mauricio A., Figueroa, Xavier F.

“…ABSTRACT The microvascular network of the microcirculation works in tight communication with surrounding tissues to control blood supply and exchange of…”
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A nondisruptive reliability approach to assess the health of microseismic sensing networks by Neira, D., Soto, G., Fontbona, J., Prado, J., Gaete, S.

“…Microseismic sensing networks are important tools for the assessment and control of geomechanical hazards in underground mining operations. In such a setting,…”
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Uncoupled permeation through large‐pore channels: ions and molecules don't always ride together by Gaete, Pablo S., Contreras, Jorge E.

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CGRP signalling inhibits NO production through pannexin-1 channel activation in endothelial cells by Gaete, Pablo S., Lillo, Mauricio A., Puebla, Mariela, Poblete, Inés, Figueroa, Xavier F.

“…Blood flow distribution relies on precise coordinated control of vasomotor tone of resistance arteries by complex signalling interactions between perivascular…”
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Large-pore connexin hemichannels function like molecule transporters independent of ion conduction by Gaete, Pablo S, Kumar, Deepak, Fernandez, Cynthia I, Valdez Capuccino, Juan M, Bhatt, Aashish, Jiang, Wenjuan, Lin, Yi-Chun, Liu, Yu, Harris, Andrew L, Luo, Yun L, Contreras, Jorge E

“…Connexin hemichannels were identified as the first members of the eukaryotic large-pore channel family that mediate permeation of both atomic ions and small…”
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Critical contribution of Na+‐Ca2+ exchanger to the Ca2+‐mediated vasodilation activated in endothelial cells of resistance arteries by Lillo, Mauricio A., Gaete, Pablo S., Puebla, Mariela, Ardiles, Nicolás M., Poblete, Inés, Becerra, Alvaro, Simon, Felipe, Figueroa, Xavier F.

“…Na+‐Ca2+ exchanger (NCX) contributes to control the intracellular free Ca2+ concentration ([Ca2+]i), but the functional activation of NCX reverse mode (NCXrm)…”
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Diffusion of nitric oxide across cell membranes of the vascular wall requires specific connexin-based channels by Figueroa, Xavier F., Lillo, Mauricio A., Gaete, Pablo S., Riquelme, Manuel A., Sáez, Juan C.

“…NO is generated within cells and frequently must be transferred to responsive neighboring cells, as occurs in the endothelium-dependent relaxation of smooth…”
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A novel voltage-clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels by Gaete, Pablo S, Lillo, Mauricio A, López, William, Liu, Yu, Jiang, Wenjuan, Luo, Yun, Harris, Andrew L, Contreras, Jorge E

“…Large-pore channels permeable to small molecules such as ATP, in addition to atomic ions, are emerging as important regulators in health and disease…”
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Novel Pannexin-1-Coupled Signaling Cascade Involved in the Control of Endothelial Cell Function and NO-Dependent Relaxation by Lillo, Mauricio A., Gaete, Pablo S., Puebla, Mariela, Burboa, Pía C., Poblete, Inés, Figueroa, Xavier F.

“…Deletion of pannexin-1 (Panx-1) leads not only to a reduction in endothelium-derived hyperpolarization but also to an increase in NO-mediated vasodilation…”
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Critical contribution of Na + -Ca 2+ exchanger to the Ca 2+ -mediated vasodilation activated in endothelial cells of resistance arteries by Lillo, Mauricio A, Gaete, Pablo S, Puebla, Mariela, Ardiles, Nicolás M, Poblete, Inés, Becerra, Alvaro, Simon, Felipe, Figueroa, Xavier F

“…Na -Ca exchanger (NCX) contributes to control the intracellular free Ca concentration ([Ca ] ), but the functional activation of NCX reverse mode (NCXrm) in…”
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Hazelnut production areas in Chile, performance of cultivars from Oregon State University, and an equation to predict performance by Mohr Fuchslocher, J.V., Navarro Gaete, S.A.

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Ca2+-activated K+ channels of small and intermediate conductance control eNOS activation through NAD(P)H oxidase by Gaete, Pablo S., Lillo, Mauricio A., Ardiles, Nicolás M., Pérez, Francisco R., Figueroa, Xavier F.

“…Ca2+-activated K+ channels (KCa) and NO play a central role in the endothelium-dependent control of vasomotor tone. We evaluated the interaction of KCa with NO…”
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El Trastorno por Déficit de Atención / Hiperactividad (TDAH) según Apoderados de Escolares by Ferretti, Romina, Gaete, Joaquín

“…El diagnóstico de trastorno por déficit de atención/hiperactividad (TDAH) es el más frecuente en la población escolar de Chile. La búsqueda de ayuda…”
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Regulation of Pannexin-1 Channel Gating by Nitric Oxide and Camp Signaling by Gaete, Pablo S., Lillo, Mauricio A., Barrera, Nelson P., Figueroa, Xavier F., Contreras, Jorge E.

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Novel Biophysical Properties of Molecular Permeation in CALHM1 and Connexin Channels by Gaete, Pablo S., Lillo, Mauricio A., Lopez, William I., Liu, Yu, Harris, Andrew L., Contreras, Jorge E.

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