Search Results - "Gaeta, FC"

ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex by PHILLIPS, M. L, NUDELMAN, E, GAETA, F. C. A, PEREZ, M, SINGHAL, A. K, HAKOMORI, S.-I, PAULSON, J. C

“…Recruitment of neutrophils to sites of inflammation is mediated in part by endothelial leukocyte adhesion molecule-1 (ELAM-1), which is expressed on activated…”
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On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs by O'Sullivan, D, Arrhenius, T, Sidney, J, Del Guercio, MF, Albertson, M, Wall, M, Oseroff, C, Southwood, S, Colon, SM, Gaeta, FC

“…We have investigated the interaction between DR1 molecules and the two antigenic peptides, tetanus toxoid 830-843 and hemagglutinin 307-319, previously known…”
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MHC interaction and T cell recognition of carbohydrates and glycopeptides by Ishioka, GY, Lamont, AG, Thomson, D, Bulbow, N, Gaeta, FC, Sette, A, Grey, HM

“…The T cell independence of complex polysaccharide Ag has suggested the possibility that carbohydrates may be incapable of T cell recognition because of a…”
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HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions by Sette, A, Sidney, J, Oseroff, C, del Guercio, MF, Southwood, S, Arrhenius, T, Powell, MF, Colon, SM, Gaeta, FC, Grey, HM

“…In the present study, we describe the definition of a DRB1*0401 (DR4w4)-specific motif. The strategy used entailed a three-step process: 1) screening a large…”
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Functional consequences of engagement of the T cell receptor by low affinity ligands by Alexander, J, Snoke, K, Ruppert, J, Sidney, J, Wall, M, Southwood, S, Oseroff, C, Arrhenius, T, Gaeta, FC, Colon, SM

“…The mechanisms involved in TCR antagonism by Ag analog/MHC have been analyzed. A detailed structure-activity relationship study indicated that modification of…”
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Effect of pH on MHC class II-peptide interactions by Sette, A, Southwood, S, O'Sullivan, D, Gaeta, FC, Sidney, J, Grey, HM

“…The effect of pH on class II-peptide interactions has been analyzed using several mouse (IAd, IAk, IEd, IEk) and human (DR1, DR5, DR7) MHC specificities, and…”
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Single amino acid changes in DR and antigen define residues critical for peptide-MHC binding and T cell recognition by Krieger, JI, Karr, RW, Grey, HM, Yu, WY, O'Sullivan, D, Batovsky, L, Zheng, ZL, Colon, SM, Gaeta, FC, Sidney, J

“…Single amino acid substitutions of Ag and MHC were used to analyze the fine structure of the influenza hemagglutinin (HA)-derived epitope (HA 307-319)…”
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Failure to demonstrate long-lived MHC saturation both in vitro and in vivo. Implications for therapeutic potential of MHC-blocking peptides by Ishioka, GY, Adorini, L, Guery, JC, Gaeta, FC, LaFond, R, Alexander, J, Powell, MF, Sette, A, Grey, HM

“…Peptides that bind with high affinity to class II MHC molecules can inhibit T cell activation both in vitro and in vivo. Thus, they have been suggested as…”
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