Search Results - "Gaertig, Jacek"

Post-translational modifications of microtubules by Wloga, Dorota, Gaertig, Jacek

“…Microtubules - polymers of tubulin - perform essential functions, including regulation of cell shape, intracellular transport and cell motility. How…”
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Posttranslational Modifications of Tubulin and Cilia by Wloga, Dorota, Joachimiak, Ewa, Louka, Panagiota, Gaertig, Jacek

“…Tubulin undergoes several highly conserved posttranslational modifications (PTMs) including acetylation, detyrosination, glutamylation, and glycylation. These…”
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The Tubulin Code by Verhey, Kristen J., Gaertig, Jacek

“…Microtubules create diverse arrays with specific cellular functions such as the mitotic spindle, cilia, and bundles inside neurons. How microtubules are…”
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IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium by Wingfield, Jenna L, Mengoni, Ilaria, Bomberger, Heather, Jiang, Yu-Yang, Walsh, Jonathon D, Brown, Jason M, Picariello, Tyler, Cochran, Deborah A, Zhu, Bing, Pan, Junmin, Eggenschwiler, Jonathan, Gaertig, Jacek, Witman, George B, Kner, Peter, Lechtreck, Karl

“…Intraflagellar transport (IFT) trains, multimegadalton assemblies of IFT proteins and motors, traffic proteins in cilia. To study how trains assemble, we…”
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Effect of α-tubulin acetylation on the doublet microtubule structure by Yang, Shun Kai, Kubo, Shintaroh, Black, Corbin Steven, Peri, Katya, Dai, Daniel, Legal, Thibault, Valente-Paterno, Melissa, Gaertig, Jacek, Bui, Khanh Huy

“…Acetylation of α-tubulin at the lysine 40 residue (αK40) by αTAT1/MEC-17 acetyltransferase modulates microtubule properties and occurs in most eukaryotic…”
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Microtubule Acetylation Promotes Kinesin-1 Binding and Transport by Reed, Nathan A., Cai, Dawen, Blasius, T. Lynne, Jih, Gloria T., Meyhofer, Edgar, Gaertig, Jacek, Verhey, Kristen J.

“…Long-distance intracellular delivery is driven by kinesin and dynein motor proteins that ferry cargoes along microtubule tracks [1, 2]. Current models…”
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LF4/MOK and a CDK-related kinase regulate the number and length of cilia in Tetrahymena by Jiang, Yu-Yang, Maier, Wolfgang, Baumeister, Ralf, Minevich, Gregory, Joachimiak, Ewa, Wloga, Dorota, Ruan, Zheng, Kannan, Natarajan, Bocarro, Stephen, Bahraini, Anoosh, Vasudevan, Krishna Kumar, Lechtreck, Karl, Orias, Eduardo, Gaertig, Jacek

“…The length of cilia is controlled by a poorly understood mechanism that involves members of the conserved RCK kinase group, and among them, the LF4/MOK…”
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Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote by Eisen, Jonathan A, Coyne, Robert S, Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R, Badger, Jonathan H, Ren, Qinghu, Amedeo, Paolo, Jones, Kristie M, Tallon, Luke J, Delcher, Arthur L, Salzberg, Steven L, Silva, Joana C, Haas, Brian J, Majoros, William H, Farzad, Maryam, Carlton, Jane M, Smith, Jr, Roger K, Garg, Jyoti, Pearlman, Ronald E, Karrer, Kathleen M, Sun, Lei, Manning, Gerard, Elde, Nels C, Turkewitz, Aaron P, Asai, David J, Wilkes, David E, Wang, Yufeng, Cai, Hong, Collins, Kathleen, Stewart, B Andrew, Lee, Suzanne R, Wilamowska, Katarzyna, Weinberg, Zasha, Ruzzo, Walter L, Wloga, Dorota, Gaertig, Jacek, Frankel, Joseph, Tsao, Che-Chia, Gorovsky, Martin A, Keeling, Patrick J, Waller, Ross F, Patron, Nicola J, Cherry, J Michael, Stover, Nicholas A, Krieger, Cynthia J, del Toro, Christina, Ryder, Hilary F, Williamson, Sondra C, Barbeau, Rebecca A, Hamilton, Eileen P, Orias, Eduardo

“…The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma…”
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Tubulin Glutamylation Regulates Ciliary Motility by Altering Inner Dynein Arm Activity by Suryavanshi, Swati, Eddé, Bernard, Fox, Laura A., Guerrero, Stella, Hard, Robert, Hennessey, Todd, Kabi, Amrita, Malison, David, Pennock, David, Sale, Winfield S., Wloga, Dorota, Gaertig, Jacek

“…How microtubule-associated motor proteins are regulated is not well understood. A potential mechanism for spatial regulation of motor proteins is provided by…”
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Asymmetrically localized proteins stabilize basal bodies against ciliary beating forces by Bayless, Brian A, Galati, Domenico F, Junker, Anthony D, Backer, Chelsea B, Gaertig, Jacek, Pearson, Chad G

“…Basal bodies are radially symmetric, microtubule-rich structures that nucleate and anchor motile cilia. Ciliary beating produces asymmetric mechanical forces…”
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Evolutionary Divergence of Enzymatic Mechanisms for Posttranslational Polyglycylation by Rogowski, Krzysztof, Juge, François, van Dijk, Juliette, Wloga, Dorota, Strub, Jean-Marc, Levilliers, Nicolette, Thomas, Daniel, Bré, Marie-Hélène, Van Dorsselaer, Alain, Gaertig, Jacek, Janke, Carsten

“…Polyglycylation is a posttranslational modification that generates glycine side chains on proteins. Here we identify a family of evolutionarily conserved…”
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Katanin regulates dynamics of microtubules and biogenesis of motile cilia by Sharma, Neeraj, Bryant, Jessica, Wloga, Dorota, Donaldson, Rachel, Davis, Richard C, Jerka-Dziadosz, Maria, Gaertig, Jacek

“…The in vivo significance of microtubule severing and the mechanisms governing its spatial regulation are not well understood. In Tetrahymena, a cell type with…”
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Tubulin Polyglutamylase Enzymes Are Members of the TTL Domain Protein Family by Janke, Carsten, Rogowski, Krzysztof, Wloga, Dorota, Regnard, Catherine, Kajava, Andrey V, Strub, Jean-Marc, Temurak, Nevzat, van Dijk, Juliette, Boucher, Dominique, van Dorsselaer, Alain, Suryavanshi, Swati, Gaertig, Jacek, Eddé, Bernard

“…Polyglutamylation of tubulin has been implicated in several functions of microtubules, but the identification of the responsible enzyme(s) has been…”
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Hyperglutamylation of Tubulin Can either Stabilize or Destabilize Microtubules in the Same Cell by Wloga, Dorota, Dave, Drashti, Meagley, Jennifer, Rogowski, Krzysztof, Jerka-Dziadosz, Maria, Gaertig, Jacek

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The LisH Domain-Containing N-Terminal Fragment is Important for the Localization, Dimerization, and Stability of Katnal2 in Tetrahymena by Joachimiak, Ewa, Waclawek, Ewa, Niziolek, Michal, Osinka, Anna, Fabczak, Hanna, Gaertig, Jacek, Wloga, Dorota

“…Katanin-like 2 protein (Katnal2) orthologs have a tripartite domain organization. Two highly conserved regions, an N-terminal LisH (Lis-homology) domain and a…”
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Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms by Wloga, Dorota, Camba, Amy, Rogowski, Krzysztof, Manning, Gerard, Jerka-Dziadosz, Maria, Gaertig, Jacek

“…The genome of Tetrahymena thermophila contains 39 loci encoding NIMA-related kinases (NRKs), an extraordinarily large number for a unicellular organism…”
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FAP206 is a microtubule-docking adapter for ciliary radial spoke 2 and dynein c by Vasudevan, Krishna Kumar, Song, Kangkang, Alford, Lea M, Sale, Winfield S, Dymek, Erin E, Smith, Elizabeth F, Hennessey, Todd, Joachimiak, Ewa, Urbanska, Paulina, Wloga, Dorota, Dentler, William, Nicastro, Daniela, Gaertig, Jacek

“…Radial spokes are conserved macromolecular complexes that are essential for ciliary motility. A triplet of three radial spokes, RS1, RS2, and RS3, repeats…”
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DYF-1 Is Required for Assembly of the Axoneme in Tetrahymena thermophila by Dave, Drashti, Wloga, Dorota, Sharma, Neeraj, Gaertig, Jacek

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Kinesin‐14 is Important for Chromosome Segregation During Mitosis and Meiosis in the Ciliate Tetrahymena thermophila by Kushida, Yasuharu, Takaine, Masak, Nakano, Kentaro, Sugai, Toshiro, Vasudevan, Krishna Kumar, Guha, Mayukh, Jiang, Yu‐Yang, Gaertig, Jacek, Numata, Osamu

“…Ciliates such as Tetrahymena thermophila have two distinct nuclei within one cell: the micronucleus that undergoes mitosis and meiosis and the macronucleus…”
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Glutamylation on α-Tubulin Is Not Essential but Affects the Assembly and Functions of a Subset of Microtubules in Tetrahymena thermophila by Wloga, Dorota, Rogowski, Krzysztof, Sharma, Neeraj, Van Dijk, Juliette, Janke, Carsten, Eddé, Bernard, Bré, Marie-Hélène, Levilliers, Nicolette, Redeker, Virginie, Duan, Jianming, Gorovsky, Martin A, Jerka-Dziadosz, Maria, Gaertig, Jacek

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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