PCR rationale for use of oral cephalosporins by oral surgery procedures

The article presents the experience of PCR detection of DNA of pathogenic germs inducing odontogenic inflammation. Pus samples of 48 patients aged 18 to 68 years undergoing oral surgery because of apical periodontal lesions and pericoronitis. The results showed microorganisms associations revealed b...

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Bibliographic Details
Published in:	Stomatologija (Moskva) Vol. 93; no. 5; p. 43
Main Authors:	Tsarev, V N, Chuvilkin, V I, Akhmedov, G D, Chuvilkina, E I, Gadzhiev, F N, Nikitin, I V
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 2014
Subjects:	Administration, Oral Adolescent Adult Aged Anti-Bacterial Agents - administration & dosage Bacteria - drug effects Bacteria - isolation & purification Bacteria - pathogenicity Cephalosporins - administration & dosage DNA, Bacterial - analysis Exudates and Transudates - microbiology Female Humans Male Middle Aged Oral Surgical Procedures Pericoronitis - microbiology Pericoronitis - surgery Polymerase Chain Reaction - methods Suppuration - microbiology Young Adult
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Summary:	The article presents the experience of PCR detection of DNA of pathogenic germs inducing odontogenic inflammation. Pus samples of 48 patients aged 18 to 68 years undergoing oral surgery because of apical periodontal lesions and pericoronitis. The results showed microorganisms associations revealed by PCR are sensitive to III generation cephalosporins. Effective oral regimen included 400 mg Ceftibuten once daily. The PCR results thus served as a rationale for use of oral cephalosporins by oral surgery procedures proved by clinical and immunological data in postoperative period.
ISSN:	0039-1735