Search Results - "Gadkari, Rishali"

Metagenomic Analysis Reveals Diverse Polyketide Synthase Gene Clusters in Microorganisms Associated with the Marine Sponge Discodermia dissoluta by Schirmer, Andreas, Gadkari, Rishali, Reeves, Christopher D, Ibrahim, Fadia, DeLong, Edward F, Hutchinson, C. Richard

“…Sponge-associated bacteria are thought to produce many novel bioactive compounds, including polyketides. PCR amplification of ketosynthase domains of type I…”
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784 BDC-2034: discovery of a CEA-targeting immune-stimulating antibody conjugate (ISAC) for solid tumors by Mallet, William, Gadkari, Rishali, Pearson, Cecelia, Torrez Dulgeroff, Laughing Bear, Luo, Angela, Luo, AAngela Luondrew, Melrose, Jennifer, Nolin, Jess, Lee, Arthur, Zhou, Matthew, Anand, Puneet, Sarma, Ganapathy, Henning, Karla, Blum, Lisa, Chapin, Steven, Bogaert, Liz, Ackerman, Shelley, Kudirka, Romas, Shen, Yuyi, Husain, Amreen, Perez, Edith, Kowanetz, Marcin, Alonso, Michael, Safina, Brian, Dornan, David

“…BackgroundCEA (CEACAM5) is a well-validated cell-surface antigen that is highly expressed in multiple solid tumors. Bolt's immune-stimulating antibody…”
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Human embryonic stem cell derived-mesenchymal stem cells: an alternative mesenchymal stem cell source for regenerative medicine therapy by Gadkari, Rishali, Zhao, Longmei, Teklemariam, Takele, Hantash, Basil M

“…To enumerate and characterize mesenchymal stem cells (MSC) derived from human embryonic stem cells (hESC) for clinical application. hESC were differentiated…”
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Abstract 366: Disease Phenotype Assessment Across a Library of iPSC-Derived Cardiomyocytes From Patient Cohorts Carrying Distinct Mutations for Familial Hypertrophic Cardiomyopathy by Tsai, Jason, Lam, Jason, Sanchez-Freire, Veronica, Gadkari, Rishali, Agarwal, Maya, Bian, Jing, Huang, Guanyi, Magal, Ashita, Lan, Feng, Lee, Andrew S

“…Abstract only Familial hypertrophic cardiomyopathy (HCM) is the leading cause of sudden cardiac death in the young, and is the most common inherited heart…”
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Abstract 2964: Targeting tumor-associated macrophages to enhance anti-tumor immunity with the Dectin-2 agonistic antibody BDC-3042 by Kenkel, Justin A., Xiao, Fang, Ho, Po Y., Nolin, Jess L., Gadkari, Rishali K., Torrez, Laughing Bear, Omstead, David T., McEachin, Katelynn A., Ptacek, Jason, Grgich, Rachel, Pearson, Cecelia I., Chun, Stefan, Kreder, Cindy L., Henning, Karla A., Kim, Han K., Xu, Lu, Chapin, Steven J., Alonso, Michael N., Ackerman, Shelley E.

“…Tumor-associated macrophages (TAMs) are the largest immune cell population in many cancers and play a key role in establishing the immunosuppressive tumor…”
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Abstract 4252: PD-L1-targeted ISAC combines myeloid cell activation, immune-checkpoint inhibition and ADCP to improve anti-tumor efficacy over anti-PD-L1 antibodies in preclinical models by Kenkel, Justin A., Gadkari, Rishali, Ho, Po Y., Blum, Lisa K., Kudirka, Romas, Henning, Karla A., Mallet, William G., Melrose, Jennifer E., Sarma, Ganapathy, Chapin, Steven J., Zhou, Matthew, Deol, Suprit, Kreder, Cindy, Shen, Yuyi, Hug, Bruce, Anand, Puneet, Lee, Arthur, Li, Hai, Ackerman, Shelley E., Safina, Brian S., Dornan, David, Alonso, Michael N., Kowanetz, Marcin

“…INTRODUCTION: Immune-stimulating antibody conjugates (ISACs) consist of tumor-targeting antibodies conjugated to immune stimulants and are designed to activate…”
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Abstract 2911: The CEA-targeted ISAC, BDC-2034, shows preclinical efficacy associated with innate immune activation, phagocytosis, and myeloid reprogramming by Blum, Lisa K., Pearson, Cecelia I., Dulgeroff, Laughing Bear Torrez, Gadkari, Rishali, Luo, Angela, Luo, Andrew, Melrose, Jennifer E., Nolin, Jess L., Li, Hai, Lee, Arthur, Zhou, Matthew N., Anand, Puneet, Sarma, Ganapathy, Henning, Karla A., Chapin, Steven J., Ackerman, Shelley E., Kudirka, Romas, Shen, Yuyi, Hug, Bruce, Perez, Edith A., Kowanetz, Marcin, Alonso, Michael N., Safina, Brian S., Dornan, David, Mallet, William G.

“…Introduction: Immune-stimulating antibody conjugates (ISACs) direct a TLR7/8 agonist into tumors through engagement of cell surface antigens to activate…”
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Metagenomic Analysis Reveals Diverse Polyketide Synthase Gene Clusters in Microortianisms Associated with the Marine Sponge Discodermia dissoluta by Schirmer, Andreas, Gadkari, Rishali, Reeves, Christopher D, Ibrahim, Fadia

“…Sponge-associated bacteria are thought to produce many novel bioactive compounds, including polyketides. PCR amplification of ketosynthase domains of type I…”
Get full text