Search Results - "Gadelha, M. R."
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New perspectives on analysing data from biological collections based on social network analytics
Published in Scientific reports (25-02-2020)“…Biological collections have been historically regarded as fundamental sources of scientific information on biodiversity. They are commonly associated with a…”
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A prospective study on the efficacy of oral estrogen in female patients with acromegaly
Published in Pituitary (01-06-2022)“…Purpose To evaluate the efficacy and safety of oral estrogen therapy in female patients of childbearing age with uncontrolled acromegaly and to verify the…”
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Baseline Assessment of Mesophotic Reefs of the Vitória-Trindade Seamount Chain Based on Water Quality, Microbial Diversity, Benthic Cover and Fish Biomass Data
Published in PloS one (19-06-2015)“…Seamounts are considered important sources of biodiversity and minerals. However, their biodiversity and health status are not well understood; therefore,…”
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Effects of GH-IGF-I excess and gonadal status on bone mineral density and body composition in patients with acromegaly
Published in Osteoporosis international (01-12-2010)“…Summary Studies on body composition and bone mineral density in acromegaly have conflicting results. Our data point to an increase in lean mass, a decrease in…”
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BioWorkbench: a high-performance framework for managing and analyzing bioinformatics experiments
Published in PeerJ (San Francisco, CA) (29-08-2018)“…Advances in sequencing techniques have led to exponential growth in biological data, demanding the development of large-scale bioinformatics experiments…”
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SISS-Geo: Leveraging Citizen Science to Monitor Wildlife Health Risks in Brazil
Published in Journal of healthcare informatics research (01-12-2019)“…The well-being of human and wildlife health involves many challenges, such as monitoring the movement of pathogens; expanding health surveillance; collecting…”
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Isolated familial somatotropinomas : Establishment of linkage to chromosome 11q13.1-11q13.3 and evidence for a potential second locus at chromosome 2p16-12
Published in The journal of clinical endocrinology and metabolism (01-02-2000)“…The majority of somatotropinomas are sporadic, although a small number occur with a familial aggregation, either as a component of an endocrine neoplasia…”
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Assessment of the frequency and risk factors for colorectal cancer in acromegaly
Published in Endocrine (14-11-2024)“…Acromegaly is associated with a possible increased risk of neoplasias, like colorectal cancer (CRC), although magnitude of this risk is…”
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Ipilimumab-induced hypophysitis: review of the literature
Published in Journal of endocrinological investigation (01-11-2015)“…Purpose Ipilimumab is a human monoclonal antibody against cytotoxic T-lymphocyte antigen 4 available as an immunotherapy mainly for advanced melanoma. It…”
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Loss of heterozygosity on chromosome 11q13 in two families with acromegaly/gigantism is independent of mutations of the multiple endocrine neoplasia type I gene
Published in The journal of clinical endocrinology and metabolism (1999)“…Familial acromegaly/gigantism occurring in the absence of multiple endocrine neoplasia type I (MEN-1) or the Carney complex has been reported in 18 families…”
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Low somatostatin receptor subtype 2, but not dopamine receptor subtype 2 expression predicts the lack of biochemical response of somatotropinomas to treatment with somatostatin analogs
Published in Journal of endocrinological investigation (2013)“…Objectives: To evaluate somatostatin receptor 2A (SSTR2A) and dopamine receptor 2 (DR2) protein expression in somatotropinomas and to relate it to response to…”
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Frequency of familial pituitary adenoma syndromes among patients with functioning pituitary adenomas in a reference outpatient clinic
Published in Journal of endocrinological investigation (01-12-2017)“…Introduction Pituitary adenomas (PA) occur mainly as sporadic disease, but familial syndromes are found in approximately 5% of cases. Identification of these…”
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A Brazilian multicentre study evaluating pregnancies induced by cabergoline in patients harboring prolactinomas
Published in Pituitary (01-04-2020)“…Objective To evaluate the maternal–fetal outcomes of CAB-induced pregnancies in patients with prolactinoma in a large cohort. Methods The prevalence of tumor…”
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Acromegaly Secondary to Growth Hormone-releasing Hormone Secreted by an Incidentally Discovered Pheochromocytoma
Published in Endocrine pathology (2007)“…Ectopic growth hormone-releasing hormone (GHRH)-secreting tumors are rare and cause acromegaly with somatotroph hyperplasia. We report a case of acromegaly…”
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MicroRNAs: Suggested role in pituitary adenoma pathogenesis
Published in Journal of endocrinological investigation (01-11-2013)“…MicroRNAs (miRNAs) are small non-coding RNA molecules that represent a major class of molecular regulators. miRNAs have been implicated in the pathogenesis of…”
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Two-dimensional speckle tracking echocardiography demonstrates no effect of active acromegaly on left ventricular strain
Published in Pituitary (01-06-2017)“…Background Speckle tracking echocardiography (STE) allows for the study of myocardial strain (ε), a marker of early and subclinical ventricular systolic…”
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Exon 3-deleted growth hormone receptor isoform is not related to worse bone mineral density or microarchitecture or to increased fracture risk in acromegaly
Published in Journal of endocrinological investigation (01-02-2020)“…Purpose Acromegaly is a cause of secondary osteoporosis and is associated with increased risk of vertebral fractures (VFs). The influence of exon 3-deleted…”
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Low risk of coronary artery disease in patients with acromegaly
Published in Endocrine (01-12-2015)“…The aims of this study are to determine the prevalence of coronary atherosclerosis in acromegalic patients and to investigate the relationship between the…”
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A survey of biodiversity informatics: Concepts, practices, and challenges
Published in Wiley interdisciplinary reviews. Data mining and knowledge discovery (01-01-2021)“…The unprecedented size of the human population, along with its associated economic activities, has an ever‐increasing impact on global environments. Across the…”
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Diagnosis and management of hyperprolactinemia: Results of a Brazilian multicenter study with 1234 patients
Published in Journal of endocrinological investigation (01-05-2008)“…Objective : The aim of the study was to evaluate clinical and laboratorial features of 1234 patients with different etiologies of hyperprolactinemia, as well…”
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