Search Results - "Gadek, James E"

Acute eosinophilic pneumonia as a reversible cause of noninfectious respiratory failure by Allen, J N, Pacht, E R, Gadek, J E, Davis, W B

“…Although chronic eosinophilic pneumonia is a well-known disorder, acute eosinophilic pneumonia has not been as well characterized. We describe the clinical…”
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Enteral nutrition with eicosapentaenoic acid, γ-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome by Pacht, Eric R, DeMichele, Stephen J, Nelson, Jeffrey L, Hart, Judy, Wennberg, Ann K, Gadek, James E

“…OBJECTIVEPreviously, we showed that acute respiratory distress syndrome patients fed an enteral diet containing eicosapentaenoic acid and γ-linolenic acid and…”
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Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome by Gadek, James E, DeMichele, Stephen J, Karlstad, Michael D, Pacht, Eric R, Donahoe, Michael, Albertson, Timothy E, Van Hoozen, Chi, Wennberg, Ann K, Nelson, Jeffrey L, Noursalehi, Mojtaba

“…OBJECTIVESRecent studies in animal models of sepsis-induced acute respiratory distress syndrome (ARDS) have shown that a low-carbohydrate, high-fat diet…”
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The Pathophysiology of Pulmonary Diffusion Impairment in Human Immunodeficiency Virus Infection by DIAZ, PHILIP T, KING, MARK A, PACHT, ERIC R, WEWERS, MARK D, GADEK, JAMES E, NEAL, DAVID, NAGARAJA, HAIKADY N, DRAKE, JANICE, CLANTON, THOMAS L

“…Numerous reports have demonstrated that prior to the development of acquired immunodeficiency syndrome (AIDS)-related pulmonary complications, human…”
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Increased susceptibility to pulmonary emphysema among HIV-seropositive smokers by DIAZ, P. T, KING, M. A, PACHT, E. R, WEWERS, M. D, GADEK, J. E, NAGARAJA, H. N, DRAKE, J, CLANTON, T. L

“…Previous uncontrolled reports have suggested that HIV-seropositive persons develop an accelerated form of emphysema. To characterize the risk for emphysema in…”
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Alveolar fluid glutathione decreases in asymptomatic HIV-seropositive subjects over time by Pacht, E R, Diaz, P, Clanton, T, Hart, J, Gadek, J E

“…Initial investigations demonstrated a deficiency of glutathione (GSH) in the epithelial lining fluid (ELF) of HIV-seropositive patients. In a recent study, our…”
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The interdependence of lung antioxidants and antiprotease defense in ARDS by Gadek, J E, Pacht, E R

“…As in hereditary alpha 1-antitrypsin deficiency, protease-antiprotease and oxidant-antioxidant balances play a significant role in the pathogenesis of ARDS…”
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Adverse effects of neutrophils on the lung by Gadek, J E

“…Studies of both emphysema and adult respiratory distress syndrome (ARDS) support the premise that lung injury is due to unregulated host defense mechanisms. A…”
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Surfactant treatment impairs gas exchange in a canine model of acute lung injury by Waugh, Jonathan B, Op’t Holt, Timothy B, Olson, Lynne E, Gadek, James E, Clanton, Thomas L

“…The effectiveness of surfactant (SURF) treatment in acute lung injury in the adult is controversial. In this study, we tested the effectiveness of early…”
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Interstitial lung disease: current concepts of pathogenesis, staging and therapy by Crystal, R G, Gadek, J E, Ferrans, V J, Fulmer, J D, Line, B R, Hunninghake, G W

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SPECIALIZED ENTERNAL NUTRITION, OXEPA™, SUPPRESSES INTRAPULMONARY INFLAMMATORY MEDIATORS IN PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) by Gadek, James E, DeMichele, Stephen, Nelson, Jeffrey, Pacht, Eric, Wennberg, Ann, Hart, Judy

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The protease-antiprotease balance within the human lung: implications for the pathogenesis of emphysema by Gadek, J E, Pacht, E R

“…Critical elements of the mechanisms of emphysema remain to be clarified. However, taken together, the existing evidence supports the concept that alveolar…”
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Replacement therapy in hereditary angioedema: successful treatment of acute episodes of angioedema with partly purified C1 inhibitor by Gadek, J E, Hosea, S W, Gelfand, J A, Santaella, M, Wickerhauser, M, Triantaphyllopoulos, D C, Frank, M M

“…Although considerable progress has been made during the past two decades in the use of androgens to prevent attacks of hereditary angioedema, replacement of…”
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Collagenase in the lower respiratory tract of patients with idiopathic pulmonary fibrosis by Gadek, J E, Kelman, J A, Fells, G, Weinberger, S E, Horwitz, A L, Reynolds, H Y, Fulmer, J D, Crystal, R G

“…To test the hypothesis that idiopathic pulmonary fibrosis (IPF) is mediated through collagenase present in the lower respiratory tract, we used the fiberoptic…”
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Maintenance of granuloma formation in pulmonary sarcoidosis by T lymphocytes within the lung by Hunninghake, G W, Gadek, J E, Young, Jr, R C, Kawanami, O, Ferrans, V J, Crystal, R G

“…Pulmonary granulomata of sarcoidosis are composed primarily of mononuclear phagocytic cells that are probably derived from blood monocytes. To evaluate the…”
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Bovine surfactant therapy for patients with acute respiratory distress syndrome by Gregory, T J, Steinberg, K P, Spragg, R, Gadek, J E, Hyers, T M, Longmore, W J, Moxley, M A, Cai, G Z, Hite, R D, Smith, R M, Hudson, L D, Crim, C, Newton, P, Mitchell, B R, Gold, A J

“…Lung surfactant is deficient in patients with acute respiratory distress syndrome (ARDS). We performed a randomized, prospective, controlled, open-label…”
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Complement Depletion in Cryptococcal Sepsis by Macher, Abe M, Bennett, John E, Gadek, James E, Frank, Michael M

“…Abstract Marked depletion of serum opsonins and complement (C) components was documented during cryptococcal septicemia in three patients. Phagocytic indices…”
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Response of Variant Hereditary Angioedema Phenotypes to Danazol Therapy by Gadek, James E., Hosea, Stephen W., Gelfand, Jeffrey A., Frank, Michael M.

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Immunoglobulin and complement receptors on human eosinophils and their role in cellular adherence to schistosomules by Ottesen, E A, Stanley, A M, Gelfand, J A, Gadek, J E, Frank, M M, Nash, T E, Cheever, A W

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Serum vitamin E decreases in HIV-seropositive subjects over time by Pacht, Eric R, Diaz, Phil, Clanton, Tom, Hart, Judy, Gadek, James E

“…Vitamin E is an important lipid soluble antioxidant that has a number of crucial functions including protecting lipids from oxidative damage. It also may play…”
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