Search Results - "Gadd, Samantha L"
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Ligand-Independent Dimerization of the Human Prolactin Receptor Isoforms: Functional Implications
Published in Molecular endocrinology (Baltimore, Md.) (01-11-2006)“…Prolactin (PRL) contributes to the growth of normal and malignant breast tissues. PRL initiates signaling by engaging the PRL receptor (PRLr), a transmembrane…”
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Prenatal overexpression of platelet‐derived growth factor receptor A results in central nervous system hypomyelination
Published in Brain and behavior (01-10-2021)“…Background Platelet‐derived growth factor (PDGF) signaling, through the ligand PDGF‐A and its receptor PDGFRA, is important for the growth and maintenance of…”
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New mechanisms for PRLr action in breast cancer
Published in Trends in endocrinology and metabolism (01-07-2009)“…Prolactin (PRL) is a pleiotrophic hormone that contributes to the growth of normal and malignant breast tissues. PRL signals through its receptor (PRLr), a…”
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Novel genetically engineered H3.3G34R model reveals cooperation with ATRX loss in upregulation of Hoxa cluster genes and promotion of neuronal lineage
Published in Neuro-oncology advances (01-01-2023)“…Abstract Background Pediatric high-grade gliomas (pHGGs) are aggressive pediatric CNS tumors and an important subset are characterized by mutations in H3F3A,…”
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Abstract LB-180: The genetic landscape of Wilms tumor
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Introduction: The National Cancer Institute's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) initiative seeks to characterize…”
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Differential gene expression of soluble CD8+ T‐cell mediated suppression of HIV replication in three older children
Published in Journal of medical virology (2011)“…Suppression of human immunodeficiency virus (HIV) replication by CD8+ T‐cells (CD8 suppression) contributes to survival in adults and children <1 year. Soluble…”
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Erratum: Differential gene expression of soluble CD8+ T-cell mediated suppression of HIV replication in three older children
Published in Journal of medical virology (01-03-2011)Get full text
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Acetaminophen-Induced Proliferation of Estrogen-Responsive Breast Cancer Cells Is Associated with Increases in c-myc RNA Expression and NF-κB Activity
Published in Toxicological sciences (01-04-2002)“…Studies reported here tested the hypothesis that acetaminophen stimulates proliferation of E2-responsive cells by inducing expression of E2-regulated genes…”
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DIPG-83. RBPJ-SIX1 AS A TUMOR SUPPRESSOR AXIS IN DIFFUSE INTRINSIC PONTINE GLIOMA
Published in Neuro-oncology (Charlottesville, Va.) (18-06-2024)Get full text
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Abstract 68: Increased H3K27 trimethylation is associated with decreased expression of miRNAs and bivalently modified genes in rhabdoid tumors
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Background: Rhabdoid tumors (RT) are aggressive tumors of infancy for which no effective treatment is currently available. These tumors are characterized by…”
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Prenatal overexpression of platelet‐derived growth factor receptor A results in central nervous system hypomyelination
Published in Brain and behavior (01-10-2021)Get full text
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Abstract 5353: Comprehensive Ggnomic analysis of diffuse hyperplastic perilobar nephroblastomatosis (DHPLN)
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Background: Wilms tumors (WT) commonly arise in the setting of precursor lesions known as nephrogenic rests. DHPLN is characterized by a continuous rind-like…”
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Abstract 1439: Loss of expression of SWI/SNF subunits in high risk Wilms tumor is accompanied by global gene expression changes
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Introduction: The TARGET initiative seeks to identify therapeutic targets through genomic sequencing supported by copy number and gene expression analysis. The…”
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Acetaminophen-induced proliferation of estrogen-responsive breast cancer cells is associated with increases in c-myc RNA expression and NF-kappaB activity
Published in Toxicological sciences (01-04-2002)“…Studies reported here tested the hypothesis that acetaminophen stimulates proliferation of E2-responsive cells by inducing expression of E2-regulated genes…”
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Acetaminophen-Induced Proliferation of Breast Cancer Cells Involves Estrogen Receptors
Published in Toxicology and applied pharmacology (15-03-1999)“…Previous studies have shown that acetaminophen, a common analgesic/antipyretic, induces proliferation of cultured breast cancer cells containing both estrogen…”
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