Search Results - "Gadaleta, M N"

Measurement of the 4,834-bp Mitochondrial DNA Deletion Level in Aging Rat Liver and Brain Subjected or Not to Caloric Restriction Diet by CASSANO, P, LEZZA, A M S, LEEUWENBURGH, C, CANTATORE, P, GADALETAa, M N

“…: Several studies have demonstrated an age‐related accumulation of the amount of a specific 4834‐bp mitochondrial DNA (mtDNA) deletion in different tissues of…”
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The Complete Nucleotide Sequence, Gene Organization, and Genetic Code of the Mitochondrial Genome of Paracentrotus lividus by Cantatore, P, Roberti, M, Rainaldi, G, Gadaleta, M N, Saccone, C

“…The 15,697-nucleotide sequence of Paracentrotus lividus mitochondrial DNA is reported. This genome codes for 2 rRNAs, 22 tRNAs, and 12 mRNAs which specify 13…”
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Acetyl-l-Carnitine Dietary Supplementation to Old Rats Increases Mitochondrial Transcription Factor A Content in Rat Hindlimb Skeletal Muscles by PESCE, V, FRACASSO, F, MUSICCO, C, LEZZA, A M S, CANTATORE, P, GADALETA, M N

“…: Acetyl‐l‐carnitine (ALCAR) fed to old rats has been reported to partially restore mitochondrial function and ambulatory activity. The results of the effect…”
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Correlation between mitochondrial DNA 4977-bp deletion and respiratory chain enzyme activities in aging human skeletal muscles by Lezza, A M, Boffoli, D, Scacco, S, Cantatore, P, Gadaleta, M N

“…The content of the mitochondrial DNA 4977-bp deletion and the respiratory chain enzyme activities were determined in the same human skeletal muscle specimens…”
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Cloning and characterisation of mtDBP, a DNA-binding protein which binds two distinct regions of sea urchin mitochondrial DNA by Polosa, Paola Loguercio, Roberti, Marina, Musicco, Clara, Gadaleta, Maria Nicola, Quagliariello, Ernesto, Cantatore, Palmiro

“…The cDNA for the sea urchin mitochondrial D-loop-binding protein (mtDBP), a 40 kDa protein which binds two homologous regions of mitochondrial DNA (the D-loop…”
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Lipid composition in synaptic and nonsynaptic mitochondria from rat brains and effect of aging by Ruggiero, F M, Cafagna, F, Petruzzella, V, Gadaleta, M N, Quagliariello, E

“…The cholesterol, phospholipid, and fatty acid compositions in synaptic and nonsynaptic mitochondria from rat brains and the effect of aging were studied. Both…”
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Acetyl- l-carnitine feeding to unloaded rats triggers in soleus muscle the coordinated expression of genes involved in mitochondrial biogenesis by Cassano, P., Sciancalepore, A.G., Pesce, V., Flück, M., Hoppeler, H., Calvani, M., Mosconi, L., Cantatore, P., Gadaleta, M.N.

“…The expressional profile of mitochondrial transcripts and of genes involved in the mitochondrial biogenesis pathway induced by ALCAR daily supplementation in…”
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Duplication and remoulding of tRNA genes during the evolutionary rearrangement of mitochondrial genomes by Cantatore, P, Gadaleta, M. N, Roberti, M, Saccone, C, Wilson, A. C

“…During the evolution of sea urchins, a transfer RNA gene lost its tRNA function and became part of a protein-coding gene. This functional loss of a tRNA with…”
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Rat hindlimb unloading: Soleus and Extensor Digitorum Longus histochemistry, mitochondrial DNA content and mitochondrial DNA deletions by Pesce, V, Cormio, A, Fracasso, F, Lezza, A M S, Cantatore, P, Gadaleta, M N

“…Mitochondrial phenotypic alterations, mitochondrial DNA content and mitochondrial DNA deletions in a slow, Soleus, and a fast, Extensor Digitorum Longus,…”
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The effect of aging and acetyl-L-carnitine on the activity of the phosphate carrier and on the phospholipid composition in rat heart mitochondria by Paradies, G, Ruggiero, F M, Gadaleta, M N, Quagliariello, E

“…The effect of aging and treatment with acetyl-L-carnitine on the activity of the phosphate carrier and on the phospholipid composition in rat heart…”
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Localization of Abasic Sites and Single-Strand Breaks in Mitochondrial DNA from Brain of Aged Rat, Treated or not with Caloric Restriction Diet by Lezza, A. M. S., Fallacara, F. P., Pesce, V., Leeuwenburgh, C., Cantatore, P., Gadaleta, M. N.

“…According to the “mitochondrial theory of aging” the lifelong accumulation of various kinds of damage to mitochondrial DNA (mtDNA) has been related to the…”
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MtDNA Deletions in Aging and in Nonmitochondrial Pathologies by CORMIO, A., LEZZA, A.M. S., VECCHIET, J., FELZANI, G., MARANGI, L., GUGLIELMI, F. W., FRANCAVILLA, A., CANTATORE, P., GADALETA, M. N.

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Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats by Gadaleta, M N, Rainaldi, G, Lezza, A M, Milella, F, Fracasso, F, Cantatore, P

“…In order to understand the cause of the reduced mitochondrial DNA transcription in heart and brain of senescent rat previously reported, we focused our…”
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Carnitine-acylcarnitine translocase activity in cardiac mitochondria from aged rats: the effect of acetyl-L-carnitine by Paradies, Giuseppe, Ruggiero, Francesca Maria, Petrosillo, Giuseppe, Gadaleta, Maria Nicola, Quagliariello, Ernesto

“…Age-related changes in mitochondrial fatty acids metabolism may underlie the progressive decline in cardiac function. The effect of aging and acute treatment…”
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Age-related mitochondrial genotypic and phenotypic alterations in human skeletal muscle by Pesce, V, Cormio, A, Fracasso, F, Vecchiet, J, Felzani, G, Lezza, A M, Cantatore, P, Gadaleta, M N

“…To have a clearer picture of how mitochondrial damages are associated to aging, a comprehensive study of phenotypic and genotypic alterations was carried out,…”
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Mitochondrial DNA transcription and translation in aged rat. Effect of acetyl-L-carnitine by Gadaleta, M N, Petruzzella, V, Daddabbo, L, Olivieri, C, Fracasso, F, Loguercio Polosa, P, Cantatore, P

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DmTTF, a novel mitochondrial transcription termination factor that recognises two sequences of Drosophila melanogaster mitochondrial DNA by Roberti, Marina, Polosa, Paola Loguercio, Bruni, Francesco, Musicco, Clara, Gadaleta, Maria Nicola, Cantatore, Palmiro

“…Using a combination of bioinformatic and molecular biology approaches a Drosophila melanogaster protein, DmTTF, has been identified, which exhibits sequence…”
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The effect of aging and acetyl-L-carnitine on the function and on the lipid composition of rat heart mitochondria by Paradies, G, Ruggiero, F M, Petrosillo, G, Gadaleta, M N, Quagliariello, E

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Content of mitochondrial DNA and of three mitochondrial RNAs in developing and adult rat cerebellum by Renis, M, Cantatore, P, Loguercio Polosa, P, Fracasso, F, Gadaleta, M N

“…The content of DNA and of 16S rRNA and of two mRNAs, i.e., the mRNA for the cytochrome c oxidase subunit I and the mRNA for one subunit of the NADH…”
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Tissue-specific effect of age and caloric restriction diet on mitochondrial DNA content by Cassano, P, Sciancalepore, A G, Lezza, A M S, Leeuwenburgh, C, Cantatore, P, Gadaleta, M N

“…The effect of age and caloric-restriction (CR) diet on mitochondrial DNA (mtDNA) content in different rat tissues was investigated. A decrease of the mtDNA…”
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