Search Results - "Gadaleta, Gennaro"

Chronic Inflammation in Obesity and Cancer Cachexia by Divella, Rosa, Gadaleta Caldarola, Gennaro, Mazzocca, Antonio

“…Chronic inflammation has long been linked to obesity and related conditions such as type 2 diabetes and metabolic syndrome. According to current research, the…”
Get full text

First-line immune checkpoint inhibitor-based combinations in unresectable hepatocellular carcinoma: current management and future challenges by Rizzo, Alessandro, Ricci, Angela Dalia, Gadaleta-Caldarola, Gennaro, Brandi, Giovanni

“…Immunotherapy has recently taken on an extremely important role in medical oncology, as first- or later-line treatment in several tumor types, and recent years…”
Get more information

Lenvatinib plus pembrolizumab: the next frontier for the treatment of hepatocellular carcinoma? by Rizzo, Alessandro, Dadduzio, Vincenzo, Ricci, Angela Dalia, Massari, Francesco, Di Federico, Alessandro, Gadaleta-Caldarola, Gennaro, Brandi, Giovanni

“…While sorafenib monotherapy represented the mainstay of medical treatment for advanced hepatocellular carcinoma (HCC) patients for more than a decade, novel…”
Get more information

Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges by Rizzo, Alessandro, Dadduzio, Vincenzo, Lombardi, Lucia, Ricci, Angela Dalia, Gadaleta-Caldarola, Gennaro

“…Ampullary carcinomas (ACs) represent a rare entity, accounting for approximately 0.2% of all gastrointestinal solid tumors and 20% of all periampullary cancers…”
Get full text

Effects of sitagliptin or metformin added to pioglitazone monotherapy in poorly controlled type 2 diabetes mellitus patients by Derosa, Giuseppe, Maffioli, Pamela, Salvadeo, Sibilla A.T, Ferrari, Ilaria, Ragonesi, Pietro D, Querci, Fabrizio, Franzetti, Ivano G, Gadaleta, Gennaro, Ciccarelli, Leonardina, Piccinni, Mario N, D'Angelo, Angela, Cicero, Arrigo F.G

“…Abstract The aim of the study was to compare the effects of the addition of sitagliptin or metformin to pioglitazone monotherapy in poorly controlled type 2…”
Get full text

The Mediterranean Lifestyle to Contrast Low-Grade Inflammation Behavior in Cancer by Divella, Rosa, Marino, Graziella, Infusino, Stefania, Lanotte, Laura, Gadaleta-Caldarola, Gaia, Gadaleta-Caldarola, Gennaro

“…A healthy diet and an active lifestyle are both effective ways to prevent, manage, and treat many diseases, including cancer. A healthy, well-balanced diet not…”
Get full text

Current and Future Role of Neoadjuvant Chemoimmunotherapy for Early Triple-Negative Breast Cancer: Which Way to Go Forward by Rizzo, Alessandro, Cusmai, Antonio, Gadaleta-Caldarola, Gennaro, Palmiotti, Gennaro

“…Immunotherapy has revolutionized previous triple-negative breast cancer (TNBC) treatment algorithms, prompting researchers and clinicians to consider the…”
Get full text

Pemigatinib in Intrahepatic Cholangiocarcinoma: A Work in Progress by Gadaleta-Caldarola, Gennaro, Rizzo, Alessandro, Dadduzio, Vincenzo, Lombardi, Lucia, Gadaleta-Caldarola, Arianna, Infusino, Stefania, Cusmai, Antonio, Citrigno, Claudia, Palmiotti, Gennaro

“…Cholangiocarcinoma (CCA) is the second most frequent primary liver cancer, following hepatocellular carcinoma (HCC). Progress in the molecular understanding of…”
Get full text

Synergizing Immunotherapy and Antibody-Drug Conjugates: New Horizons in Breast Cancer Therapy by Pinto, Antonello, Guarini, Chiara, Giampaglia, Marianna, Sanna, Valeria, Melaccio, Assunta, Lanotte, Laura, Santoro, Anna Natalizia, Pini, Francesca, Cusmai, Antonio, Giuliani, Francesco, Gadaleta-Caldarola, Gennaro, Fedele, Palma

“…The advent of immunotherapy and antibody-drug conjugates (ADCs) have revolutionized breast cancer treatment, offering new hope to patients. However,…”
Get full text

Pathological Complete Response to Neoadjuvant Chemoimmunotherapy for Early Triple-Negative Breast Cancer: An Updated Meta-Analysis by Rizzo, Alessandro, Cusmai, Antonio, Massafra, Raffaella, Bove, Samantha, Comes, Maria Colomba, Fanizzi, Annarita, Rinaldi, Lucia, Acquafredda, Silvana, Gadaleta-Caldarola, Gennaro, Oreste, Donato, Zito, Alfredo, Giotta, Francesco, Lorusso, Vito, Palmiotti, Gennaro

“…Immune checkpoint inhibitors (ICIs) have made a breakthrough in the systemic treatment for metastatic triple-negative breast cancer (TNBC) patients. However,…”
Get full text

Systemic Treatments for Metastatic Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Old Certainties and New Frontiers by Rizzo, Alessandro, Cusmai, Antonio, Massafra, Raffaella, Bove, Samantha, Comes, Maria Colomba, Fanizzi, Annarita, Gadaleta-Caldarola, Gennaro, Oreste, Donato, Zito, Alfredo, Giotta, Francesco, Lorusso, Vito, Palmiotti, Gennaro

“…Epidermal growth factor receptor 2 (EGFR2, also known as HER2) overexpression and/or amplification confers a more aggressive clinical behavior but also…”
Get full text

Second-Line Chemotherapy in Elderly Patients with Advanced Biliary Tract Cancer: A Multicenter Real-World Study by Rizzo, Alessandro, Salati, Massimiliano, Frega, Giorgio, Merz, Valeria, Caputo, Francesco, Di Federico, Alessandro, Palloni, Andrea, Carloni, Riccardo, Ricci, Angela Dalia, Gadaleta-Caldarola, Gennaro, Messina, Carlo, Spallanzani, Andrea, Gelsomino, Fabio, Benatti, Stefania, Luppi, Gabriele, Melisi, Davide, Dominici, Massimo, Brandi, Giovanni

“…Objectives: The ABC-06 and the NIFTY trials recently established the role of second-line chemotherapy (2L) in patients with advanced biliary tract cancer…”
Get full text

Safety evaluation of Datopotamab deruxtecan for triple-negative breast cancer: a meta-analysis by Gadaleta-Caldarola, Gennaro, Lanotte, Laura, Infusino, Stefania, Gadaleta-Caldarola, Arianna, Schipilliti, Francesca Matilde, Citrigno, Claudia, Petrarota, Cataldo, Cusmai, Antonio, Rizzo, Alessandro

“…TROP-2 is emerging as a valid and fruitful strategy in triple-negative breast cancer (TNBC) patients, and several agents are currently under evaluation,…”
Get full text

Circulating Levels of PAI-1 and SERPINE1 4G/4G Polymorphism Are Predictive of Poor Prognosis in HCC Patients Undergoing TACE by Divella, Rosa, Daniele, Antonella, Abbate, Ines, Savino, Eufemia, Casamassima, Porzia, Sciortino, Giancarlo, Simone, Giovanni, Gadaleta-Caldarola, Gennaro, Fazio, Vito, Gadaleta, Cosimo Damiano, Sabbà, Carlo, Mazzocca, Antonio

“…Abstract Although several molecular markers have been proposed as prognostic of disease progression in Hepatocellular carcinoma (HCC), predictive markers of…”
Get full text

Paziente con carcinoma mammario oligometastatico HER2-positivo, lungosopravvivente in trattamento con lapatinib/ capecitabina dopo resezione e termoablazione polmonare by Gadaleta-Caldarola, Gennaro

“…In una paziente HER2-positiva in post-menopausa, con metastasi polmonare e linfonodali mediastiniche, il trattamento di mantenimento con lapatinib +…”
Get full text

Eribulin in Male Patients With Breast Cancer: The First Report of Clinical Outcomes by Giotta, Francesco, Acito, Luigi, Candeloro, Giampiero, Del Medico, Pietro, Gadaleta‐Caldarola, Gennaro, Giordano, Guido, Gueli, Rossana, Lugini, Antonio, Magri, Valentina, Mandarà, Marta, Masci, Giovanna, Pisconti, Salvatore, Pistelli, Mirco, Rizzi, Anna, Salesi, Nello, Schirone, Alessio, Scognamiglio, Giovanni, Tedeschi, Maria, Zucchinelli, Patrizia

“…Background. Evidence on the management and treatment of male breast cancer is scant. We report the analysis of a multicenter Italian series of patients with…”
Get full text

Single-step Therapy — Feasibility and Safety of Simultaneous Transarterial Chemoembolization and Radiofrequency Ablation for Hepatic Malignancies by Gadaleta, Cosmo, Catino, Annamaria, Ranieri, Girolamo, Fazio, Vito, Gadaleta-Caldarola, Gennaro, Cramarossa, Antonio, Armenise, Francesco, Canniello, Eugenio, Vinciarelli, Gianluca, Laricchia, Giuseppe, Mattioli, Vittorio

“…Background: Radiofrequency thermal ablation (RFA) has been demonstrated to be useful for the treatment of liver neoplasms. The study aimed to evaluate the…”
Get full text

Needle Insertion Difficulty Algorithm (NIDA): A novel pilot study to predict Huber needle insertion difficulty in totally implanted devices by Civetta, Giuseppe, Lombardi, Lucia, Lanotte, Antonio, Delvecchio, Anna Maria, Colonnata, Melania, Todisco, Angela, Cristallo, Rosa, Marcone, Andrea, Somma, Michele, Vitale, Elsa, Giammarinaro, Maria Pia, Bruno, Giovanni, Caldarola, Gennaro Gadaleta

“…Safeguarding of venous assets in cancer patients provides for positioning vascular devices. In totally implanted central venous access devices, hereinafter…”
Get full text

Preferences of Patients with Advanced Colorectal Cancer for Treatment with Oral or Intravenous Chemotherapy by Mastroianni, Candida M., Viscomi, Caterina, Ceniti, Silvia, Simone, Rosanna De, Filice, Aldo, Caldarola, Gennaro Gadaleta, Infusino, Stefania, Manfredi, Caterina, Rea, Antonio, Sandomenico, Claudia, Turano, Salvatore, Serranò, Francesco, Condemi, Giovanni, Cortese, Carla, Prantera, Tullia, Palazzo, Salvatore

“…Background: In recent years, patient-reported outcomes such as health-related quality of life have become important areas of clinician focus in general cancer…”
Get full text

Which role for predictors of response to immune checkpoint inhibitors in hepatocellular carcinoma? by Rizzo, Alessandro, Cusmai, Antonio, Gadaleta-Caldarola, Gennaro, Palmiotti, Gennaro

“…Hepatocellular carcinoma (HCC) remains a frequently diagnosed malignancy worldwide, still representing an important cause of cancer-related death. Recent years…”
Get more information