Search Results - "Gadad, Shrikanth"
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Discovery, Annotation, and Functional Analysis of Long Noncoding RNAs Controlling Cell-Cycle Gene Expression and Proliferation in Breast Cancer Cells
Published in Molecular cell (20-08-2015)“…We describe a computational approach that integrates GRO-seq and RNA-seq data to annotate long noncoding RNAs (lncRNAs), with increased sensitivity for…”
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Implications of Enhancer Transcription and eRNAs in Cancer
Published in Cancer research (Chicago, Ill.) (15-08-2021)“…Despite extensive progress in developing anticancer therapies, therapy resistance remains a major challenge that promotes disease relapse. The changes that…”
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3
Long noncoding RNAs and cancer, an overview
Published in Steroids (01-05-2018)“…Long noncoding RNAs (lncRNAs) are implicated in several biological processes, including but not limited to cardiovascular physiology, reproduction,…”
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The paradigm of drug resistance in cancer: an epigenetic perspective
Published in Bioscience reports (01-04-2022)“…Innate and acquired resistance towards the conventional therapeutic regimen imposes a significant challenge for the successful management of cancer for…”
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ZMYND8 Is a Regulator of Sonic Hedgehog Signaling in ATRA-Mediated Differentiation of Neuroblastoma Cells
Published in Biochemistry (Easton) (18-06-2024)“…Zinc Finger MYND (Myeloid, Nervy, and DEAF-1) type containing 8 (ZMYND8) is a crucial epigenetic regulator that plays a multifaceted role in governing a…”
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TCF19 and p53 regulate transcription of TIGAR and SCO2 in HCC for mitochondrial energy metabolism and stress adaptation
Published in The FASEB journal (01-09-2021)“…Alteration in glucose homeostasis during cancer metabolism is an important phenomenon. Though several important transcription factors have been well studied in…”
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Emerging Roles of Estrogen-Regulated Enhancer and Long Non-Coding RNAs
Published in International journal of molecular sciences (25-05-2020)“…Genome-wide RNA sequencing has shown that only a small fraction of the human genome is transcribed into protein-coding mRNAs. While once thought to be "junk"…”
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Structure and expression of the long noncoding RNA gene MIR503 in humans and non-human primates
Published in Molecular and cellular endocrinology (15-06-2020)“…Recent technical and other advances in genomics provide unique opportunities to improve our understanding of human physiology and disease predisposition…”
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TCF19 Promotes Cell Proliferation through Binding to the Histone H3K4me3 Mark
Published in Biochemistry (Easton) (04-02-2020)“…Transcription factor 19 (TCF19) plays critical roles in type 1 diabetes and the maintenance of pancreatic β cells. Recent studies have also implicated TCF19 in…”
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Long noncoding RNAs in cancer: From discovery to therapeutic targets
Published in Advances in clinical chemistry (2020)“…Long noncoding RNAs (lncRNAs) have recently gained considerable attention as key players in biological regulation; however, the mechanisms by which lncRNAs…”
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GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment
Published in Nature communications (16-12-2016)“…Some polypeptide N-acetyl-galactosaminyltransferases (GALNTs) are associated with cancer, but their function in organ-specific metastasis remains unclear…”
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Functional Characterization of lncRNA152 as an Angiogenesis-Inhibiting Tumor Suppressor in Triple-Negative Breast Cancers
Published in Molecular cancer research (03-11-2022)“…Long noncoding RNAs have been implicated in many of the hallmarks of cancer. Herein, we found that the expression of lncRNA152 (lnc152; a.k.a. DRAIC), which we…”
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PARP-1 Regulates Estrogen-Dependent Gene Expression in Estrogen Receptor α-Positive Breast Cancer Cells
Published in Molecular cancer research (01-10-2021)“…Poly(ADP-ribose) polymerase-1 (PARP-1) has gained considerable attention as a target for therapeutic inhibitors in breast cancers. Previously we showed that…”
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14
Mycoplasma genitalium and M. pneumoniae Regulate a Distinct Set of Protein-Coding Genes in Epithelial Cells
Published in Frontiers in immunology (11-10-2021)“…and are two significant mycoplasmas that infect the urogenital and respiratory tracts of humans. Despite distinct tissue tropisms, they both have similar…”
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15
Progress and prospect of nanotechnology for cardiac fibrosis treatment
Published in Interdisciplinary medicine (Richmond, Vic. Print) (01-10-2023)“…Cardiac fibrosis is the excessive accumulation of extracellular matrix components in the heart, leading to reduced cardiac functionality and heart failure…”
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Mycobacterium smegmatis secreting methionine sulfoxide reductase A (MsrA) modulates cellular processes in mouse macrophages
Published in Biochimie (01-08-2023)“…Methionine sulfoxide reductase A (MsrA) is an antioxidant repair enzyme that reduces the oxidized methionine (Met-O) in proteins to methionine (Met). Its…”
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Genome-wide analysis and functional prediction of the estrogen-regulated transcriptional response in the mouse uterus
Published in Biology of reproduction (14-02-2020)“…The ovarian hormones estrogen and progesterone orchestrate the transcriptional programs required to direct functions of the uterus for initiation and…”
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Live Attenuated Vaccines against Tuberculosis: Targeting the Disruption of Genes Encoding the Secretory Proteins of Mycobacteria
Published in Vaccines (Basel) (01-05-2024)“…Tuberculosis (TB), a chronic infectious disease affecting humans, causes over 1.3 million deaths per year throughout the world. The current preventive vaccine…”
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ZMYND8 suppresses MAPT213 LncRNA transcription to promote neuronal differentiation
Published in Cell death & disease (05-09-2022)“…Zinc Finger transcription factors are crucial in modulating various cellular processes, including differentiation. Chromatin reader Zinc Finger MYND (Myeloid,…”
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Acetylated NPM1 Localizes in the Nucleoplasm and Regulates Transcriptional Activation of Genes Implicated in Oral Cancer Manifestation
Published in Molecular and Cellular Biology (01-09-2009)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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