Search Results - "Gada, D"

PKC regulation of ion channels: The involvement of PIP2 by Gada, Kirin D., Logothetis, Diomedes E.

“…Ion channels are integral membrane proteins whose gating has been increasingly shown to depend on the presence of the low-abundance membrane phospholipid,…”
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Expectations and experiences of patients undergoing orthognathic surgery — a retrospective survey of 115 patients by Gada, D, Padhye, M, Venkateshwar, G

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Inflammation impacts androgen receptor signaling in basal prostate stem cells through interleukin 1 receptor antagonist by Cooper, Paula O., Yang, Jiang, Wang, Hsing-Hui, Broman, Meaghan M., Jayasundara, Shyaman Madhawa, Sahoo, Subhransu Sekhar, Yan, Bingyu, Awdalkreem, Gada D., Cresswell, Gregory M., Wang, Liang, Goossens, Emery, Lanman, Nadia A., Doerge, Rebecca W., Zheng, Faye, Cheng, Liang, Alqahtani, Saeed, Crist, Scott A., Braun, Robert E., Kazemian, Majid, Jerde, Travis J., Ratliff, Timothy L.

“…Chronic prostate inflammation in patients with benign prostate hyperplasia (BPH) correlates with the severity of symptoms. How inflammation contributes to…”
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IKACh is constitutively active via PKC epsilon in aging mediated atrial fibrillation by Chang, Mengmeng, Gada, Kirin D., Chidipi, Bojjibabu, Tsalatsanis, Athanasios, Gibbons, Justin, Remily-Wood, Elizabeth, Logothetis, Diomedes E., Oberstaller, Jenna, Noujaim, Sami F.

“…Atrial fibrillation (AF), the most common abnormal heart rhythm, is a major cause for stroke. Aging is a significant risk factor for AF; however, specific…”
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Optogenetic dephosphorylation of phosphatidylinositol 4,5 bisphosphate in Xenopus laevis oocytes by Gada, Kirin D., Xu, Yu, Winn, Brenda T., Masotti, Meghan, Kawano, Takeharu, Vaananen, Heikki, Plant, Leigh D.

“…Here, we present a protocol for optogenetic dephosphorylation of the phosphoinositide PI(4,5)P2 at the plasma membrane of Xenopus laevis oocytes. We first…”
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Current role of computed tomography angiography in fibula flap: a rare case study of peroneal arteria magna by Takalkar, S, Gite, M, Venkateshwar, G, Padhye, M, Madiwale, G, Jain, M, Dahiya, S, Sawarkar, P, Gada, D, Borkhade, N

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An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins by Gada, Kirin D., Kawano, Takeharu, Plant, Leigh D., Logothetis, Diomedes E.

“…The PKC family consists of several closely related kinases. These enzymes regulate the function of proteins through the phosphorylation of hydroxyl groups on…”
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Mechanism of PKCε regulation of cardiac GIRK channel gating by Gada, Kirin D, Chang, Mengmeng, Chandrashekar, Aishwarya, Plant, Leigh D, Noujaim, Sami F, Logothetis, Diomedes E

“…G-protein-gated inwardly rectifying potassium (GIRK) channel activity is regulated by the membrane phospholipid, phosphatidylinositol-4,5-bisphosphate (PI 4,5P…”
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Altered voltage-dependence revealed in an inactivation-deficient mutant of Nav1.4 via optogenetic PI(4,5)P2 dephosphorylation by Kissell, Ralph C., Gada, Kirin D., Kamuene, Jordie M., Chandrashekar, Aishwarya, Plant, Leigh D.

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A novel small-molecule selective activator of homomeric GIRK4 channels by Cui, Meng, Xu, Keman, Gada, Kirin D., Shalomov, Boris, Ban, Michelle, Eptaminitaki, Giasemi C., Kawano, Takeharu, Plant, Leigh D., Dascal, Nathan, Logothetis, Diomedes E.

“…G protein–sensitive inwardly rectifying potassium (GIRK) channels are important pharmaceutical targets for neuronal, cardiac, and endocrine diseases. Although…”
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Hypoxia inhibits the cardiac IK1 current through SUMO targeting Kir2.1 activation by PIP2 by Xu, Yu, Yang, Yuchen, Chandrashekar, Aishwarya, Gada, Kirin D., Masotti, Meghan, Baggetta, Austin M., Connolly, Jenna G., Kawano, Takeharu, Plant, Leigh D.

“…Cardiovascular diseases remain the leading cause of death worldwide. Most deaths are sudden and occur secondary to the occlusion of coronary arteries resulting…”
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PI(4,5)P2 regulates the gating of NaV1.4 channels by Gada, Kirin D, Kamuene, Jordie M, Chandrashekar, Aishwarya, Kissell, R Charles, Yauch, Anne K, Plant, Leigh D

“…Voltage-gated sodium (NaV) channels are densely expressed in most excitable cells and activate in response to depolarization, causing a rapid influx of Na+…”
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Hypoxia inhibits the cardiac I K1 current through SUMO targeting Kir2.1 activation by PIP2 by Xu, Yu, Yang, Yuchen, Chandrashekar, Aishwarya, Gada, Kirin D, Masotti, Meghan, Baggetta, Austin M, Connolly, Jenna G, Kawano, Takeharu, Plant, Leigh D

“…Cardiovascular diseases remain the leading cause of death worldwide. Most deaths are sudden and occur secondary to the occlusion of coronary arteries resulting…”
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Imaging Membrane Proteins Using Total Internal Reflection Fluorescence Microscopy (TIRFM) in Mammalian Cells by Gada, Kirin D, Kamuene, Jordie M, Kawano, Takeharu, Plant, Leigh D

“…The cell surfaceome is of vital importance across physiology, developmental biology, and disease states alike. The precise identification of proteins and their…”
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p53 and Ki-67 expression in epithelial gastric dysplasia and in gastric cancer by Testino, G, Gada, D, De Iaco, F, Cornaggia, M

“…The aim of this study was to examine p53 and Ki-67 expression in relation to high grade dysplasia (HGD) clinical behaviour. A retrospective, cross sectional…”
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Distance measures for effective clustering of ARIMA time-series by Kalpakis, K., Gada, D., Puttagunta, V.

“…Much environmental and socioeconomic time-series data can be adequately modeled using autoregressive integrated moving average (ARIMA) models. We call such…”
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Phase 1 trial of gemcitabine with bortezomib in elderly patients with advanced solid tumors by Bommakanti, Satya V, Dudek, Arkadiusz Z, Khatri, Amit, Kirstein, Mark N, Gada, Purvi D

“…Bortezomib, a proteasome inhibitor, has synergistic antitumor activity with gemcitabine, an antimetabolite, in preclinical and clinical studies. The safety of…”
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REAL-TIME ULTRASOUND USE FOR PLEURAL SAMPLING by SAKHUJA, PRIYAL, GADA, KUNAL D, QADEER, ASEM H

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THE USE OF BEDSIDE ULTRASOUND IN THE MANAGEMENT OF COMMUNITY-ACQUIRED PNEUMONIA by GUPTA, ANUJ, LESSING, ALEXIE, GADA, KUNAL D, AHMAD, SAHAR

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Basopenia as an indicator of ovulation (a short term clinical study) by Soni, R, Bose, S, Gada, D, Potnis, V

“…In the present study 60 cases age ranging from 18-40 years were studied for variation in the absolute basophil count on the different days of menstrual cycle…”
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