Search Results - "Gacesa, R"

Environmental factors shaping the gut microbiome in a Dutch population by Gacesa, R., Kurilshikov, A., Vich Vila, A., Sinha, T., Klaassen, M. A. Y., Bolte, L. A., Andreu-Sánchez, S., Chen, L., Collij, V., Hu, S., Dekens, J. A. M., Lenters, V. C., Björk, J. R., Swarte, J. C., Swertz, M. A., Jansen, B. H., Gelderloos-Arends, J., Jankipersadsing, S., Hofker, M., Vermeulen, R. C. H., Sanna, S., Harmsen, H. J. M., Wijmenga, C., Fu, J., Zhernakova, A., Weersma, R. K.

“…The gut microbiome is associated with diverse diseases 1 – 3 , but a universal signature of a healthy or unhealthy microbiome has not been identified, and…”
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Molecular photoprotection of human keratinocytes in vitro by the naturally occurring mycosporine‐like amino acid palythine by Lawrence, K.P., Gacesa, R., Long, P.F., Young, A.R.

“…Summary Background Solar ultraviolet radiation (UVR) induces molecular and genetic changes in the skin, which result in skin cancer, photoageing and…”
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Gut feelings: the relations between depression, anxiety, psychotropic drugs and the gut microbiome by Brushett, S., Gacesa, R., Vich Vila, A., Brandao Gois, M.F., Andreu-Sánchez, S., Swarte, J.C., Klaassen, M.A.Y., Collij, V., Sinha, T., Bolte, L.A., Wu, J., Swertz, M., de Kroon, M.L.A., Reijneveld, S.A., Wijmenga, C., Weersma, R.K., Fu, J., van Loo, H.M., Kurilshikov, A., Zhernakova, A.

“…The gut microbiome is involved in the bi-directional relationship of the gut - brain axis. As most studies of this relationship are small and do not account…”
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A combination of fecal calprotectin and human beta-defensin 2 facilitates diagnosis and monitoring of inflammatory bowel disease by Gacesa, R., Vich Vila, A., Collij, V., Mujagic, Z., Kurilshikov, A., Voskuil, M.D., Festen, E.A.M., Wijmenga, C., Jonkers, D.M.A.E., Dijkstra, G., Fu, J., Zhernakova, A., Imhann, F., Weersma, R.K.

“…Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) show a large overlap in clinical presentation, which presents diagnostic challenges. As a…”
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DOP30 Cross-ethnic microbiome analyses identify shared and specific signals for Northern Indian IBD patients by Singh, A, Gacesa, R, Juyal, G, Joshi, M, Midah, V, Thelma, B K, Weersma, R K, Sood, A

“…Abstract Background Clinical manifestation of the inflammatory bowel disease (IBD) shows considerable variation across the world. We hypothesized these…”
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DOP20 Changes in systemic antibody epitope repertoires from preclinical to established Inflammatory Bowel Disease by Bourgonje, A R, Andreu-Sánchez, S, Gacesa, R, Klompus, S, Kalka, I N, Leviatan, S, Weinberger, A, Segal, E, Fu, J, Zhernakova, A, Vogl, T, Weersma, R K

“…Abstract Background Inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), exhibit unique immunological changes…”
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DOP69 Longitudinal gut microbiome dynamics in relation to disease flares in Inflammatory Bowel Disease, pilot data from the IBD-Tracker study by Gacesa, R, Klaassen, M A Y, Collij, V, Björk, J R, Blankenstein, A D, Jansen, B H, Dijkstra, G, Visschedijk, M, Festen, E A M, Ananthakrishnan, A, Alm, E, Weersma, R K

“…Abstract Background The pathogenetic mechanisms that lead to IBD flares are unknown and the absence of reliable predictive biomarkers results in a therapeutic…”
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P241 Systemic redox status associates with disease activity and clinical phenotypes in Inflammatory Bowel Disease by Geertsema, S, Bourgonje, A R, Gacesa, R, Fagundes, R R, Spekhorst, L M, Hu, S, Kannan, A K, Ruane, D, de Jong, S, Jansen, B H, Bulthuis, M L C, Reinders-Luinge, M, Weersma, R K, van Goor, H, Dijkstra, G, Faber, K N

“…Abstract Background Oxidative stress is a key pathophysiological mechanism in inflammatory bowel diseases (IBD). Systemic levels of oxidative stress are…”
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P086 Mucosal microbiota modulate host intestinal immune signatures in Inflammatory Bowel Disease by Hu, S, Bourgonje, A R, Gacesa, R, Jansen, B H, Bangma, A, Hidding, I, Festen, E A M, van Dullemen, H M, Visschedijk, M C, Dijkstra, G, Harmsen, H J M, Vich Vila, A, Spekhorst, L M, Weersma, R K

“…Abstract Background Host intestinal immune gene signatures and microbial dysregulations expose potential mechanisms in the pathogenesis of inflammatory bowel…”
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DOP46 Mucosal host-microbe interactions associate with clinical phenotypes in Inflammatory Bowel Disease by Bourgonje, A, Hu, S, Gacesa, R, Jansen, B H, Björk, J R, Bangma, A, Hidding, I J, van Dullemen, H M, Visschedijk, M C, Faber, K N, Dijkstra, G, Harmsen, H J M, Festen, E A M, Vich Vila, A, Spekhorst, L M, Weersma, R K

“…Abstract Background Host intestinal immune gene signatures and microbial dysregulations expose potential mechanisms in the pathogenesis of inflammatory bowel…”
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P006 Host-genetics, dysbiosis, and clinical history explains fecal metabolic alterations in patients with Inflammatory Bowel Disease by Vich Vila, A, Hu, S, Andreu-Sánchez, S, Collij, V, Jansen, D, Ruigrok, R, Abu-Ali, G, Parkinson, J, Al Garawi, A, Schneider, J, Kurilshikov, A, Björk, J, Gacesa, R, Fu, J, Zhernakova, A, Weersma, R K

“…Abstract Background The pathogenesis of inflammatory bowel diseases is characterized by gastrointestinal dysbiosis. Small molecules -or metabolites- present in…”
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WCN23-0748 HEALTH-RELATED QUALITY OF LIFE IS LINKED TO THE GUT MICROBIOME IN KIDNEY TRANSPLANT RECIPIENTS by KNOBBE, T.J., Swarte, J.C., Björk, J.R., Gacesa, R., Zhang, S., Vich Vila, A., Investigators, T., Kremer, D., de Meijer, V.E., Blokzijl, H., Zhernakova, A., Fu, J., Harmsen, H.J.M., Bakker, S.J.L., Weersma, R.K.

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P102 Increased abundance of gut microbial virulence genes and pro-inflammatory pathways during Crohn’s disease exacerbations by Klaassen, M, Imhann, F, Collij, V, Vich Vila, A, Gacesa, R, Fu, J, Zhernakova, A, Wijmenga, C, Weersma, R

“…Abstract Background Crohn’s disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract characterised by alternating periods of exacerbation…”
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OP01 In-depth characterisation of host genetics and gut microbiome unravels novel host–microbiome interactions in inflammatory bowel disease by Hu, S, Vich Vila, A, Gacesa, R, Collij, V, Xavier, R, Stevens, C, Daly, M, Wijmenga, C, van Dullemen, H, Dijkstra, G, Visschedijk, M, Festen, E, Fu, J, Kurilshikov, A, Zhernakova, A, Weersma, R

“…Abstract Background A large number of host genetic factors, as well as changes in the gut microbiota, are known to determine aetiology and pathogenesis of…”
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