Search Results - "Gabriella da Rosa Monte Machado"
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Evaluation of 8-Hydroxyquinoline Derivatives as Hits for Antifungal Drug Design
Published in Medical mycology (Oxford) (01-10-2017)“…Abstract Clioquinol is an 8-hydroxyquinoline derivative that was widely used from the 1950s to 1970s as an oral antiparasitic agent. In 1970, the oral forms…”
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A chloroacetamide derivative as a potent candidate for fusariosis treatment
Published in Brazilian journal of microbiology (01-09-2022)“…Fusariosis has presented a significant increase in their incidence in the last years. This epidemiological panorama probably is due to the increasing profile…”
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Development of a Clioquinol Nanocarrier as a New, Promising Option for the Treatment of Dermatomycosis
Published in Pharmaceutics (01-02-2023)“…Dermatomycosis is a common fungal infection, and its treatment is limited by few antifungal agents. Clioquinol (CQ) is an antiparasitic agent that has been…”
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Essential oil and residual distillation water of Pterocaulon polystachyum DC: composition, antifungal activity, and mathematical modeling of steam distillation
Published in Plant biosystems (02-11-2022)“…The steam distillation applied to the aerial parts of Pterocaulon polystachyum DC (Asteraceae) afforded essential oil and an aqueous residue, which is a…”
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Anti-Acanthamoeba metallopharmaceuticals: Amoebicidal activity and synergistic effect of copper(II) coordination compound
Published in Biometals (01-10-2024)“…Acanthamoeba spp. emerged as a clinically important pathogen related to amoebic keratitis. It is among the main causes of corneal transplantation and vision…”
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Development of biopolymer films loaded with fluconazole and thymol for resistant vaginal candidiasis
Published in International journal of biological macromolecules (01-08-2024)“…Vulvovaginal candidiasis (VVC) is an opportunistic infection caused by a fungus of the Candida genus, affecting approximately 75 % of women during their…”
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Lipid core nanoparticles as a broad strategy to reverse fluconazole resistance in multiple Candida species
Published in Colloids and surfaces, B, Biointerfaces (01-03-2019)“…[Display omitted] •LCNF is an alternative to overcome fluconazole fungal resistance in Candida.•LNCF was effective against resistant strains that have active…”
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Clioquinol is a promising preventive morphological switching compound in the treatment of Candida infections linked to the use of intrauterine devices
Published in Journal of medical microbiology (01-11-2018)“…Candida biofilm infections are frequently linked to the use of biomaterials and are of clinical significance because they are commonly resistant to…”
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Quinolines derivatives as promising new antifungal candidates for the treatment of candidiasis and dermatophytosis
Published in Brazilian journal of microbiology (01-12-2020)“…Fungal infections have emerged as a current serious global public health problem. The main problem involving these infections is the expansion of multidrug…”
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Ex vivo potential of a quinoline-derivative nail lacquer as a new alternative for dermatophytic onychomycosis treatment
Published in Journal of medical microbiology (01-03-2021)“…Onychomycosis infections currently show a significant increase, affecting about 10 % of the world population. is the main agent responsible for about 80 % of…”
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Chloroacetamide derivatives as a promising topical treatment for fungal skin infections
Published in Mycologia (04-07-2019)“…The aim of this study was to evaluate the antifungal potential of 11 chloroacetamide derivatives and derivative incorporated into a film-forming system (FFS)…”
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Anti-Candida activity of Tripodanthus acutifolius (Loranthaceae), mechanism of action and toxicity parameters
Published in Scientific electronic archives (31-05-2021)“…The extensive use of azoles antifungals against infections caused by Candida species has been contributing to the selection of resistant strains to this…”
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In vitro Antifungal Susceptibility of Agents for Superficial Phaeohyphomycosis
Published in Revista da Sociedade Portuguesa de Dermatologia e Venereologia (14-07-2020)“…The selection of fungal isolates resistant to available therapy associated with an increase in the number of immunosuppressed patients has contributed to the…”
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Candidemia associated with COVID-19: risk factors and predisposition in critical patients
Published in Clinical and Biomedical Research (01-07-2024)“…Introduction: Coronavirus diasease 19 (COVID-19) is an infection caused by the new coronavirus - SARS-CoV-2 in 2019. The infection quickly spread throughout…”
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Corticosteroid therapy associated with Covid-19: an ally or a risk factor for the establishment of secondary fungal co-infections?
Published in Clinical and Biomedical Research (03-03-2023)Get full text
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Corticosterapy associated to COVID-19
Published in Clinical and Biomedical Research (01-03-2023)“…Introduction: the corticosteroids therapy to combat inflammation caused by SARS-CoV-2 appears to be a risk factor for the secondary fungal co-infections…”
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Candidemia associated with COVID-19: risk factors and predisposition in critical patients
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Influence of detergents and sodium hypochlorite on Yarrowia lipolytica biofilms in utensils used in industrial production of colonial cheese
Published in Anais da Academia Brasileira de Ciências (01-01-2020)“…Abstract The formation of microbial biofilms in materials used in the industrial production of dairy may lead to deterioration of these foods. Yarrowia…”
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