Search Results - "Gabriele, Antonio"
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The Use of Surface Plasmon Resonance to Study the Interactions of Proteins Involved in Conformational Diseases: Experimental Approaches for New Therapeutical Perspectives
Published in Current medicinal chemistry (01-01-2023)“…In recent years, the scientific community has been trying to tackle different diseases by using unifying and holistic approaches based on the concept that it…”
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An SPR-based method for Hill coefficient measurements: the case of insulin-degrading enzyme
Published in Analytical and bioanalytical chemistry (01-07-2022)“…Insulin-degrading enzyme (IDE) is a highly conserved zinc metallopeptidase and is capable to catalytically cleave several substrates besides insulin, playing a…”
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A geometrical solution underlies general neural principle for serial ordering
Published in Nature communications (19-09-2024)“…A general mathematical description of how the brain sequentially encodes knowledge remains elusive. We propose a linear solution for serial learning tasks,…”
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The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells' Ubiquitylome
Published in International journal of molecular sciences (17-09-2024)“…Glaucoma is chronic optic neuropathy whose pathogenesis has been associated with the altered metabolism of Trabecular Meshwork Cells, which is a cell type…”
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A pre‐processing technique to decrease inspection time in glass tube production lines
Published in IET image processing (01-08-2021)“…In case of glass tube for pharmaceutical applications, high‐quality defect detection is made via inspection systems based on computer vision. The processing…”
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IDE Degrades Nociceptin/Orphanin FQ through an Insulin Regulated Mechanism
Published in International journal of molecular sciences (10-09-2019)“…Insulin-degrading enzyme (IDE) was applied to catalyze hydrolysis of Nociceptin/Orphanin 1-16 (OFQ/N) to show the involvement of the enzyme in degradation of…”
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Carbon dots fluorescence can be used to distinguish isobaric peptide and to monitor protein oligomerization dynamics
Published in Methods (San Diego, Calif.) (01-10-2024)“…[Display omitted] •A newly developed method based on carbon dots fluorescence is described in details;•The newly developed method allows distinguish among…”
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Relationships, Current Issues, Safety and Efficacy of Oral Anticoagulation in Cancer Patients with Atrial Fibrillation
Published in Journal of clinical medicine (16-10-2023)“…A relationship between malignancy and impaired hemostasis has been proven, and balancing clotting and bleeding risks can be challenging. Half of cancer…”
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Systematic Review and Meta-Analysis of Oral Anticoagulant Therapy in Atrial Fibrillation Cancer Patients
Published in Cancers (30-04-2023)“…(1) Introduction: Cancer and atrial fibrillation (AF) are increasingly coexisting medical challenges. These two conditions share an increased thrombotic and…”
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A novel SPR based method for measuring diffusion coefficients: From small molecules to supramolecular aggregates
Published in Biosensors and bioelectronics. X (01-05-2023)“…Investigating peptides and proteins conformations in vitro is of paramount importance in biochemistry and cell biology, as the understanding of many…”
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Staged rotational atherectomy in a patient with acute ST-elevation myocardial infarction: a case report and review of the literature
Published in Giornale italiano di cardiologia (2006) (01-02-2022)“…Rotational atherectomy represents an option to improve the treatment of calcified/undilatable coronary stenoses, but its use in ST-elevation myocardial…”
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HDAC6 inhibition disrupts HDAC6-P300 interaction reshaping the cancer chromatin landscape
Published in Clinical epigenetics (18-08-2024)“…Histone deacetylases (HDACs) are crucial regulators of gene expression, DNA synthesis, and cellular processes, making them essential targets in cancer…”
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The rise of rationality in blockchain dynamics
Published in New journal of physics (01-12-2023)“…Abstract Taking informed decisions, namely acting rationally, is an individual attitude of paramount relevance in nature and human societies. In this work, we…”
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Fast Blob and Air Line Defects Detection for High Speed Glass Tube Production Lines
Published in Journal of imaging (25-10-2021)“…During the production of pharmaceutical glass tubes, a machine-vision based inspection system can be utilized to perform the high-quality check required by the…”
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Low‐density lipoprotein‐cholesterol lowering in individuals at intermediate cardiovascular risk: Percent reduction or target level?
Published in Clinical cardiology (Mahwah, N.J.) (01-03-2018)“…Background Recommendations for blood cholesterol management differ across different guidelines. Hypothesis Lipid‐lowering strategies based on low‐density…”
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Cardiovascular Risk Stratification and Statin Eligibility Based on the Brazilian vs. North American Guidelines on Blood Cholesterol Management
Published in Arquivos brasileiros de cardiologia (01-06-2017)“…The best way to select individuals for lipid-lowering treatment in the population is controversial. In healthy individuals in primary prevention: to assess the…”
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Persistent Depressive Symptoms are Independent Predictors of Low-Grade Inflammation Onset Among Healthy Individuals
Published in Arquivos brasileiros de cardiologia (01-08-2017)“…Depressive symptoms are independently associated with an increased risk of cardiovascular disease (CVD) among individuals with non-diagnosed CVD. The…”
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The Expected Cardiovascular Benefit of Plasma Cholesterol Lowering with or Without LDL-C Targets in Healthy Individuals at Higher Cardiovascular Risk
Published in Arquivos brasileiros de cardiologia (01-06-2017)“…There is controversy whether management of blood cholesterol should be based or not on LDL-cholesterol (LDL-c) target concentrations. To compare the estimated…”
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Percepção Inadequada do Risco Cardiovascular e Baixo Conhecimento sobre Hipercolesterolemia Familiar em Indivíduos com Hipercolesterolemia Grave
Published in Arquivos brasileiros de cardiologia (08-04-2021)“…Resumo Fundamento Indivíduos com hipercolesterolemia grave apresentam alto risco de desenvolver doença cardiovascular aterosclerótica (DCVA). Muitos deles…”
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