Search Results - "Gabriela M. Gomes, M."
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Herd immunity under individual variation and reinfection
Published in Journal of mathematical biology (01-07-2022)“…We study a susceptible-exposed-infected-recovered (SEIR) model considered by Aguas et al. (In: Herd immunity thresholds for SARS-CoV-2 estimated from unfolding…”
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Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold
Published in Journal of theoretical biology (07-05-2022)“…[Display omitted] •Variation in susceptibility/exposure responds to selection by natural infection.•Selection on susceptibility/exposure flattens epidemic…”
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Modelling the epidemiology of residual Plasmodium vivax malaria in a heterogeneous host population: A case study in the Amazon Basin
Published in PLoS computational biology (13-03-2020)“…The overall malaria burden in the Americas has decreased dramatically over the past two decades, but residual transmission pockets persist across the Amazon…”
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Variation in Wolbachia effects on Aedes mosquitoes as a determinant of invasiveness and vectorial capacity
Published in Nature communications (16-04-2018)“…Wolbachia has been introduced into Aedes aegypti mosquitoes to control the spread of arboviruses, such as dengue, chikungunya and Zika. Studies showed that…”
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The impact of active case finding on transmission dynamics of tuberculosis: A modelling study
Published in PloS one (19-11-2021)“…In the last decade, active case finding (ACF) strategies for tuberculosis (TB) have been implemented in many diverse settings, with some showing large…”
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A Bayesian framework for parameter estimation in dynamical models
Published in PloS one (24-05-2011)“…Mathematical models in biology are powerful tools for the study and exploration of complex dynamics. Nevertheless, bringing theoretical results to an agreement…”
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Controlling malaria using livestock-based interventions: a one health approach
Published in PloS one (22-07-2014)“…Where malaria is transmitted by zoophilic vectors, two types of malaria control strategies have been proposed based on animals: using livestock to divert…”
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Tuberculosis in Brazil and cash transfer programs: A longitudinal database study of the effect of cash transfer on cure rates
Published in PloS one (22-02-2019)“…Tuberculosis incidence is disproportionately high among people in poverty. Cash transfer programs have become an important strategy in Brazil fight…”
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Reply to: “Enhancement of Aedes aegypti susceptibility to dengue by Wolbachia is not supported”
Published in Nature communications (30-11-2020)Get full text
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A missing dimension in measures of vaccination impacts
Published in PLoS pathogens (01-03-2014)“… Any infectious processes must depend in some fashion on dose, and empirical evidence exists for an effect of exposure dose on the probability of transmission…”
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Introducing risk inequality metrics in tuberculosis policy development
Published in Nature communications (06-06-2019)“…Global stakeholders including the World Health Organization rely on predictive models for developing strategies and setting targets for tuberculosis care and…”
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A BRIEF APPRAISAL OF THE COVID-19 PANDEMIC IN PORTUGAL
Published in Revstat (15-10-2020)“…In this issue, Nunes et al. ([4]) review the prominent role embraced by statistical and epidemiological researchers in conducting societies through the…”
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Model-based inference from multiple dose, time course data reveals Wolbachia effects on infection profiles of type 1 dengue virus in Aedes aegypti
Published in PLoS neglected tropical diseases (20-03-2018)“…Infection is a complex and dynamic process involving a population of invading microbes, the host and its responses, aimed at controlling the situation…”
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Ten-year performance of Influenzanet: ILI time series, risks, vaccine effects, and care-seeking behaviour
Published in Epidemics (01-12-2015)“…Highlights • ILI incidences from Influenzanet and ECDC correlate well over multiple seasons. • Northern Europeans visit their GP later and less often than…”
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Limited available evidence supports theoretical predictions of reduced vaccine efficacy at higher exposure dose
Published in Scientific reports (01-03-2019)“…Understanding the causes of vaccine failure is important for predicting disease dynamics in vaccinated populations and planning disease interventions. Pathogen…”
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Vaccine Effects on Heterogeneity in Susceptibility and Implications for Population Health Management
Published in mBio (21-11-2017)“…Heterogeneity in host susceptibility is a key determinant of infectious disease dynamics but is rarely accounted for in assessment of disease control measures…”
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Expanding vaccine efficacy estimation with dynamic models fitted to cross-sectional prevalence data post-licensure
Published in Epidemics (01-03-2016)“…Highlights • We study vaccine efficacy (VE) against pathogen acquisition in SI and SIS systems with vaccination. • We outline the nonlinear relationship…”
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On the Final Size of Epidemics with Seasonality
Published in Bulletin of mathematical biology (01-11-2009)“…We first study an SIR system of differential equations with periodic coefficients describing an epidemic in a seasonal environment. Unlike in a constant…”
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The role of weather on the relation between influenza and influenza-like illness
Published in Journal of theoretical biology (07-04-2012)“…Influenza epidemics, enabled by viral antigenic drift, occur invariably each winter in temperate climates. However, attempts to correlate the magnitude of…”
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Clinical trials: The mathematics of falling vaccine efficacy with rising disease incidence
Published in Vaccine (08-06-2016)“…Reports of unexplained discrepancies in the efficacy of vaccines, as estimated from randomised controlled trials in different parts of the world, are…”
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