Search Results - "Gabriel Criado"

Therapies Targeting Trained Immune Cells in Inflammatory and Autoimmune Diseases by Municio, Cristina, Criado, Gabriel

“…The concept of trained immunity has recently emerged as a mechanism contributing to several immune mediated inflammatory conditions. Trained immunity is…”
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Macrophages from the synovium of active rheumatoid arthritis exhibit an activin A-dependent pro-inflammatory profile by Soler Palacios, Blanca, Estrada-Capetillo, Lizbeth, Izquierdo, Elena, Criado, Gabriel, Nieto, Concha, Municio, Cristina, González-Alvaro, Isidoro, Sánchez-Mateos, Paloma, Pablos, Jose Luis, Corbí, Angel L, Puig-Kröger, Amaya

“…Rheumatoid arthritis (RA) is a chronic inflammatory disease whose pathogenesis and severity correlates with the presence of macrophage‐derived pro‐inflammatory…”
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Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype by Del Rey, Manuel J, Valín, Álvaro, Usategui, Alicia, Ergueta, Sandra, Martín, Eduardo, Municio, Cristina, Cañete, Juan D, Blanco, Francisco J, Criado, Gabriel, Pablos, José L

“…Accumulation of senescent cells has been associated with pro-inflammatory effects with deleterious consequences in different human diseases. The purpose of…”
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Hif-1α Knockdown Reduces Glycolytic Metabolism and Induces Cell Death of Human Synovial Fibroblasts Under Normoxic Conditions by Del Rey, Manuel J., Valín, Álvaro, Usategui, Alicia, García-Herrero, Carmen M., Sánchez-Aragó, María, Cuezva, José M., Galindo, María, Bravo, Beatriz, Cañete, Juan D., Blanco, Francisco J., Criado, Gabriel, Pablos, José L.

“…Increased glycolysis and HIF-1α activity are characteristics of cells under hypoxic or inflammatory conditions. Besides, in normal O 2 environments, elevated…”
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Protocol for the induction of arthritis in C57BL/6 mice by Williams, Richard O, Inglis, Julia J, Šimelyte, Egle, McCann, Fiona E, Criado, Gabriel

“…Collagen-induced arthritis is a well-validated, but strain-dependent mouse model of rheumatoid arthritis, with H-2 q and H-2 r strains showing the greatest…”
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The PI-3-Kinase P110α Catalytic Subunit of T Lymphocytes Modulates Collagen-Induced Arthritis by Montes-Casado, María, Ojeda, Gloria, Criado, Gabriel, Rojo, José M, Portolés, Pilar

“…The phosphatidylinositol 3-kinase (PI3K) family of enzymes plays a determinant role in inflammation and autoimmune responses. However, the implication of the…”
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Alternative p38 MAPKs Are Essential for Collagen‐Induced Arthritis by Criado, Gabriel, Risco, Ana, Alsina‐Beauchamp, Dayanira, Pérez‐Lorenzo, María J., Escós, Alejandra, Cuenda, Ana

“…Objective The role of most p38 MAPK isoforms in inflammatory arthritis is not known. This study was undertaken to evaluate p38γ and p38δ deficiency in the…”
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A profibrotic role for thymic stromal lymphopoietin in systemic sclerosis by Usategui, Alicia, Criado, Gabriel, Izquierdo, Elena, Del Rey, Manuel J, Carreira, Patricia E, Ortiz, Pablo, Leonard, Warren J, Pablos, José L

“…[corrected] Systemic sclerosis (SSc) is an autoimmune disease characterised by progressive fibrosis. Although SSc shares pathogenetic features with other…”
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TFAM-deficient mouse skin fibroblasts - an ex vivo model of mitochondrial dysfunction by Del Rey, Manuel J, Meroño, Carolina, Municio, Cristina, Usategui, Alicia, Mittelbrunn, María, García-Consuegra, Inés, Criado, Gabriel, Pablos, José L

“…Mitochondrial dysfunction associates with several pathological processes and contributes to chronic inflammatory and ageing-related diseases. Mitochondrial…”
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Evidence of telomere attrition and a potential role for DNA damage in systemic sclerosis by Usategui, Alicia, Municio, Cristina, Arias-Salgado, Elena G, Martín, María, Fernández-Varas, Beatriz, Del Rey, Manuel J, Carreira, Patricia, González, Antonio, Criado, Gabriel, Perona, Rosario, Pablos, José L

“…To investigate the role of cell senescence in systemic sclerosis (SSc), we analyzed telomere shortening (TS) in SSc patients and the effect of targeting DNA…”
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Synovial fibroblast hyperplasia in rheumatoid arthritis: Clinicopathologic correlations and partial reversal by anti–tumor necrosis factor therapy by Izquierdo, Elena, Cañete, Juan D., Celis, Raquel, Del Rey, Manuel J., Usategui, Alicia, Marsal, Sara, Sanmartí, Raimon, Criado, Gabriel, Pablos, José L.

“…Objective Synovial fibroblast (SF) hyperplasia contributes to the pathogenesis of rheumatoid arthritis (RA), but quantitative information on this process is…”
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Microthrombotic Renal Vascular Lesions Are Associated to Increased Renal Inflammatory Infiltration in Murine Lupus Nephritis by Gonzalo-Gil, Elena, García-Herrero, Carmen, Toldos, Oscar, Usategui, Alicia, Criado, Gabriel, Pérez-Yagüe, Sonia, Barber, Domingo F, Pablos, Jose L, Galindo, Maria

“…Vascular microthrombotic lesions in lupus nephritis with or without antiphospholipid antibodies may relate to worse renal outcomes. Whether microthrombotic…”
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Characteristics of TCR/CD3 complex CD3ε chains of regulatory CD4+ T (Treg) lymphocytes: role in Treg differentiation in vitro and impact on Treg in vivo by Jose M. Rojo, Gloria Ojeda, Yenny Y. Acosta, Maria Montes-Casado, Gabriel Criado, Pilar Portolés

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Inhibitory Role of Growth Hormone in the Induction and Progression Phases of Collagen-Induced Arthritis by Villares, Ricardo, Criado, Gabriel, Juarranz, Yasmina, Lopez-Santalla, Mercedes, García-Cuesta, Eva M, Rodríguez-Frade, José M, Leceta, Javier, Lucas, Pilar, Pablos, José Luis, Martínez-A, Carlos, Garin, Marina I, Gomariz, Rosa P, Mellado, Mario

“…Evidence indicates an intimate connection between the neuroendocrine and the immune systems. A number of and studies have demonstrated growth hormone (GH)…”
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IL6/sIL6R regulates TNFα-inflammatory response in synovial fibroblasts through modulation of transcriptional and post-transcriptional mechanisms by Valin, Alvaro, Del Rey, Manuel J., Municio, Cristina, Usategui, Alicia, Romero, Marina, Fernández-Felipe, Jesús, Cañete, Juan D., Blanco, Francisco J., Ruano, Yolanda, Criado, Gabriel, Pablos, José L.

“…Introduction The clinical efficacy of specific interleukin-6 inhibitors has confirmed the central role of IL6 in rheumatoid arthritis (RA). However the local…”
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Use of Lentiviral Particles As a Cell Membrane-Based mFasL Delivery System for In Vivo Treatment of Inflammatory Arthritis by Rodríguez-Frade, José M, Guedán, Anabel, Lucas, Pilar, Martínez-Muñoz, Laura, Villares, Ricardo, Criado, Gabriel, Balomenos, Dimitri, Reyburn, Hugh T, Mellado, Mario

“…During budding, lentiviral particles (LVP) incorporate cell membrane proteins in the viral envelope. We explored the possibility of harnessing this process to…”
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Comparative Study of Senescent Th Biomarkers in Healthy Donors and Early Arthritis Patients. Analysis of VPAC Receptors and Their Influence by Villanueva-Romero, Raúl, Lamana, Amalia, Flores-Santamaría, Marissa, Carrión, Mar, Pérez-García, Selene, Triguero-Martínez, Ana, Tomero, Eva, Criado, Gabriel, Pablos, José L, González-Álvaro, Isidoro, Martínez, Carmen, Juarranz, Yasmina, Gomariz, Rosa P, Gutiérrez-Cañas, Irene

“…Pro-inflammatory CD4 CD28 T cells are characteristic of immunosenescence, but also of several autoimmune/inflammatory diseases. Vasoactive intestinal peptide…”
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Complement regulatory protein Crry/p65-mediated signaling in T lymphocytes: role of its cytoplasmic domain and partitioning into lipid rafts by Jimenez-Perianez, A, Ojeda, G, Criado, G, Sanchez, A, Fini, E, Madrenas, J, Rojo, J M, Portoles, P

“…Crry/p65 is a type I glycoprotein, which protects mouse T cells from complement attack. We have previously shown that complement receptor I‐related protein…”
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Peritoneal dialysis solutions inhibit the differentiation and maturation of human monocyte-derived dendritic cells: effect of lactate and glucose-degradation products by Puig-Kröger, Amaya, Muñiz-Pello, Oscar, Selgas, Rafael, Criado, Gabriel, Bajo, M-Auxiliadora, Sánchez-Tomero, Jose A, Alvarez, Vicente, del Peso, Gloria, Sánchez-Mateos, Paloma, Holmes, Clifford, Faict, Dirk, López-Cabrera, Manuel, Madrenas, Joaquín, Corbí, Angel L

“…Peritoneal dialysis (PD) is a well‐established therapy for end‐stage renal failure, but its efficiency is limited by recurrent peritonitis. As PD solutions…”
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ZAP-70-Independent Ca2+ Mobilization and Erk Activation in Jurkat T Cells in Response to T-Cell Antigen Receptor Ligation by Shan, Xiaochuan, Balakir, Richard, Criado, Gabriel, Wood, Jason S., Seminario, Maria-Cristina, Madrenas, Joaquin, Wange, Ronald L.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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