Search Results - "Gabriel, Aurelie"
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Common genetic variations in telomere length genes and lung cancer: a Mendelian randomisation study and its novel application in lung tumour transcriptome
Published in eLife (20-04-2023)“…Genome-wide association studies (GWASs) have identified genetic susceptibility variants for both leukocyte telomere length (LTL) and lung cancer…”
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Needlestack: an ultra-sensitive variant caller for multi-sample next generation sequencing data
Published in NAR genomics and bioinformatics (01-06-2020)“…Abstract The emergence of next-generation sequencing (NGS) has revolutionized the way of reaching a genome sequence, with the promise of potentially providing…”
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Metacells untangle large and complex single-cell transcriptome networks
Published in BMC bioinformatics (13-08-2022)“…Single-cell RNA sequencing (scRNA-seq) technologies offer unique opportunities for exploring heterogeneous cell populations. However, in-depth single-cell…”
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4
Building and analyzing metacells in single-cell genomics data
Published in Molecular systems biology (02-07-2024)“…The advent of high-throughput single-cell genomics technologies has fundamentally transformed biological sciences. Currently, millions of cells from complex…”
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Robust estimation of cancer and immune cell-type proportions from bulk tumor ATAC-Seq data
Published in eLife (09-10-2024)“…Assay for Transposase-Accessible Chromatin sequencing (ATAC-Seq) is a widely used technique to explore gene regulatory mechanisms. For most ATAC-Seq data from…”
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A molecular map of lung neuroendocrine neoplasms
Published in Gigascience (30-10-2020)“…Abstract Background Lung neuroendocrine neoplasms (LNENs) are rare solid cancers, with most genomic studies including a limited number of samples. Recently,…”
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Genetic Analysis of Lung Cancer and the Germline Impact on Somatic Mutation Burden
Published in JNCI : Journal of the National Cancer Institute (08-08-2022)“…Abstract Background Germline genetic variation contributes to lung cancer (LC) susceptibility. Previous genome-wide association studies (GWAS) have implicated…”
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Differential Orthopedia Homeobox expression in pulmonary carcinoids is associated with changes in DNA methylation
Published in International journal of cancer (15-06-2022)“…Limited number of tumor types have been examined for Orthopedia Homeobox (OTP) expression. In pulmonary carcinoids, loss of expression is a strong indicator of…”
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Abstract 3744: Differential Orthopedia Homeobox (OTP) expression in pulmonary carcinoids is associated with changes in DNA methylation
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Introduction: Limited number of tumor types have been examined for Orthopedia Homeobox (OTP) expression. In pulmonary carcinoids, loss of expression is a…”
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Robust estimation of cancer and immune cell-type proportions from bulk tumor ATAC-Seq data
Published in eLife (09-10-2024)“…Assay for Transposase-Accessible Chromatin sequencing (ATAC-Seq) is a widely used technique to explore gene regulatory mechanisms. For most ATAC-Seq data from…”
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Transcriptome‐wide association study reveals candidate causal genes for lung cancer
Published in International journal of cancer (01-04-2020)“…We have recently completed the largest GWAS on lung cancer including 29,266 cases and 56,450 controls of European descent. The goal of our study has been to…”
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Deformation and cracking during sintering of bimaterial components processed from ceramic and metal powder mixes. Part I: Experimental investigation
Published in Mechanics of materials (01-10-2012)“…► Continuous observation of the sintering of a bilayer powder compact. ► Comparison of the strains in the bilayer with those measured during free sintering. ►…”
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Deformation and cracking during sintering of bimaterial components processed from ceramic and metal powder mixes. Part II: Numerical simulation
Published in Mechanics of materials (01-10-2012)“…► Identification of constitutive equations of powder compacts during sintering. ► Finite element simulation of the sintering of bilayer components. ► Good…”
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Constitutive modeling of the behaviour of cermet compacts during reaction sintering
Published in Powder technology (25-03-2011)“…This study deals with the identification of a constitutive equation describing the mechanical behaviour of a nickel ferrite based cermet during sintering. This…”
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Journal Article Conference Proceeding -
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Preparation and electrical properties of dense micro-cermets made of nickel ferrite and metallic copper
Published in Solid state sciences (01-08-2009)“…Dense micro-cermets made of nickel ferrites and copper micrometric particles were obtained from partial reduction under hydrogenated atmosphere at 350 °C of…”
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