Search Results - "Gabriëls, Isabelle J."

Gene transcription ontogeny of hypothalamic-pituitary-thyroid axis development in early-life stage fathead minnow and zebrafish by Vergauwen, Lucia, Cavallin, Jenna E., Ankley, Gerald T., Bars, Chloé, Gabriëls, Isabelle J., Michiels, Ellen D.G., Fitzpatrick, Krysta R., Periz-Stanacev, Jelena, Randolph, Eric C., Robinson, Serina L., Saari, Travis W., Schroeder, Anthony L., Stinckens, Evelyn, Swintek, Joe, Van Cruchten, Steven J., Verbueken, Evy, Villeneuve, Daniel L., Knapen, Dries

“…[Display omitted] •Control fish were sampled at 25 time points covering embryo-larval development.•Transcript levels of 12 thyroid-related genes were…”
Get full text

From mRNA Expression of Drug Disposition Genes to In Vivo Assessment of CYP-Mediated Biotransformation during Zebrafish Embryonic and Larval Development by Verbueken, Evy, Bars, Chloé, Ball, Jonathan S, Periz-Stanacev, Jelena, Marei, Waleed F A, Tochwin, Anna, Gabriëls, Isabelle J, Michiels, Ellen D G, Stinckens, Evelyn, Vergauwen, Lucia, Knapen, Dries, Van Ginneken, Chris J, Van Cruchten, Steven J

“…The zebrafish ( ) embryo is currently explored as an alternative for developmental toxicity testing. As maternal metabolism is lacking in this model, knowledge…”
Get full text

Optimizing the Use of Zebrafish Feeding Trials for the Safety Evaluation of Genetically Modified Crops by Gabriëls, Isabelle J, Vergauwen, Lucia, De Boevre, Marthe, Van Dongen, Stefan, Blust, Ronny, De Saeger, Sarah, Eeckhout, Mia, De Loose, Marc, Knapen, Dries

“…In Europe, the toxicological safety of genetically modified (GM) crops is routinely evaluated using rodent feeding trials, originally designed for testing oral…”
Get full text

Permanent Deiodinase Type 2 Deficiency Strongly Perturbs Zebrafish Development, Growth, and Fertility by Houbrechts, Anne M, Delarue, Julie, Gabriëls, Isabelle J, Sourbron, Jo, Darras, Veerle M

“…Iodothyronine deiodinases are selenocysteine-containing enzymes that activate or inactivate thyroid hormones (THs). Deiodinase type 2 (Dio2) catalyzes the…”
Get full text

Ontogeny of key zebrafish genes involved in the disposition of xenobiotics from the embryonic until the juvenile stage by Bars, Chloé, Verbueken, Evy, Periz-Stanaćev, Jelena, Vergauwen, Lucia, Michiels, Ellen D.G., Stinckens, Evelyn, Gabriëls, Isabelle J., Knapen, Dries, Van Ginneken, Chris, Van Cruchten, Steven

Get full text