Search Results - "Gabor, Franz"
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The impact of calcium phosphate on FITC-BSA loading of sonochemically prepared PLGA nanoparticles for inner ear drug delivery elucidated by two different fluorimetric quantification methods
Published in Ultrasonics sonochemistry (01-11-2021)“…•Fluorimetric quantification of entrapped FITC-BSA is possible.•Two separate methods allow its quantification in the nanogram range.•Dequenching of FITC-BSA by…”
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Characterization of sonochemically prepared human serum albumin nanocapsules using different plant oils as core component for targeted drug delivery
Published in Ultrasonics sonochemistry (01-08-2021)“…•Proteinaceous nanocapsules (NCs) with a narrow size distribution could be prepared.•NCs with biocompatible oil cores could be produced avoiding toxic…”
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A Versatile Brij-Linker for One-Step Preparation of Targeted Nanoparticles
Published in Pharmaceutics (04-05-2023)“…: Most frequently the functionalization of nanoparticles is hampered by time-consuming, sometimes harsh conjugation and purification procedures causing…”
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A Novel Preparation Technique for Human Nasal Respiratory Mucosa to Disclose Its Glycosylation Pattern for Bioadhesive Drug Delivery
Published in Pharmaceutics (01-03-2023)“…To shed some light on glycotargeting as a potential strategy for nasal drug delivery, a reliable preparation method for human nasal mucosa samples and a tool…”
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5
Characterization of Adsorbents for Cytokine Removal from Blood in an In Vitro Model
Published in Journal of immunology research (01-01-2015)“…Introduction. Cytokines are basic targets that have to be removed effectively in order to improve the patient’s health status in treating severe inflammation,…”
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Trimethoprim-Loaded Microspheres Prepared from Low-Molecular-Weight PLGA as a Potential Drug Delivery System for the Treatment of Urinary Tract Infections
Published in ACS omega (21-04-2020)“…Commonly, therapy of urinary tract infections suffers from increasing resistance to antibiotics and the ability of uropathogenic Escherichia coli (UPEC) to…”
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The lectin–cell interaction and its implications to intestinal lectin-mediated drug delivery
Published in Advanced drug delivery reviews (03-03-2004)“…Based on the fact that oligosaccharides encode biological information, the biorecognition between lectinised drug delivery systems and glycosylated structures…”
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Increased transport of resveratrol across monolayers of the human intestinal caco-2 cells is mediated by inhibition and saturation of metabolites
Published in Pharmaceutical research (01-09-2006)“…The study's aim was to investigate the dose-dependent effect of sulfation and glucuronidation on intestinal absorption of resveratrol, a dietary constituent…”
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Trimethoprim-Loaded PLGA Nanoparticles Grafted with WGA as Potential Intravesical Therapy of Urinary Tract InfectionsStudies on Adhesion to SV-HUCs Under Varying Time, pH, and Drug-Loading Conditions
Published in ACS omega (21-07-2020)“…Intravesical therapy, already used to treat bladder cancer, is a potential treatment option for urinary tract infections. However, short dwelling time and…”
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Binding and uptake of wheat germ agglutinin-grafted PLGA-nanospheres by caco-2 monolayers
Published in Pharmaceutical research (01-10-2004)“…The Caco-2 association of lectin-grafted PLGA-nanospheres was investigated compared to plain and BSA-coated spheres. Nanospheres made from fluorescent-labeled…”
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Validation of in vitro cell culture models of the blood-brain barrier: tightness characterization of two promising cell lines
Published in Journal of pharmaceutical sciences (01-12-2008)“…In the course of the validation of blood-brain barrier in vitro models the aim of this work was to characterize two promising continuous cell lines with regard…”
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A novel tool to characterize paracellular transport : The APTS-dextran ladder
Published in Pharmaceutical research (01-07-2006)“…The aim of this work was to develop an easy, manageable, and precise analytic tool to describe the tightness of cell layers by a molecular weight ladder…”
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Noise trauma and systemic application of the selective glucocorticoid receptor modulator compound A
Published in Journal of negative results in biomedicine (11-05-2016)“…Selective glucocorticoid receptor modulators (SEGRMs) comprise a novel class of drugs promising both reduced side effects and similar pharmacological potency…”
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Stabilizer-Induced Viscosity Alteration Biases Nanoparticle Sizing via Dynamic Light Scattering
Published in Langmuir (14-08-2007)“…The size dependent features of colloids at the nanometer scale have been issues of increasingly intensive research. In order to be able to correctly relate…”
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Expression of Claudin-1, Claudin-3 and Claudin-5 in human blood–brain barrier mimicking cell line ECV304 is inducible by glioma-conditioned media
Published in Neuroscience letters (03-12-2008)“…Up to now no standard cell culture model of the blood–brain barrier is available. However, several models based on primary cells or continuous cell lines have…”
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Biomimickry of UPEC Cytoinvasion: A Novel Concept for Improved Drug Delivery in UTI
Published in Pathogens (Basel) (04-02-2016)“…Urinary tract infections (UTIs) are among the most common bacterial infections. In an increasing number of cases, pathogen (multi-)resistance hampers durable…”
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Wheat germ agglutinin binds to the epidermal growth factor receptor of artificial Caco-2 membranes as detected by silver nanoparticle enhanced fluorescence
Published in Pharmaceutical research (01-05-2003)“…The purpose of this study was to identify one of the ligands that mediate carbohydrate-specific cytoadhesion and cytoinvasion of wheat germ agglutinin…”
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Poly( d, l-lactic-co-glycolic acid) microspheres for sustained delivery and stabilization of camptothecin
Published in Journal of controlled release (20-09-1999)“…Camptothecin (CPT) and its water-insoluble derivatives are known as topoisomerase-I inhibitors exhibiting high antitumoral activity against a wide spectrum of…”
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Lectin-mediated drug targeting : Preparation, binding characteristics, and antiproliferative activity of wheat germ agglutinin conjugated doxorubicin on Caco-2 cells
Published in Pharmaceutical research (01-07-1998)“…To investigate the usefulness of wheat germ agglutinin as a targeting carrier protein for an acid-labile chemotherapeutic prodrug directed against colon…”
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Biocompatible medical implant materials with binding sites for a biodegradable drug-delivery system
Published in Nanotechnology, science and applications (01-01-2011)“…Feasibility studies have been carried out for development of a biocompatible coating of medical implant materials allowing the binding of biodegradable…”
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