Search Results - "Gabazza, E.C."

What has been learnt from the thrombin‐activatable fibrinolysis inhibitor‐deficient mouse? by MORSER, J., GABAZZA, E. C., MYLES, T., LEUNG, L. L. K.

“…Thrombin‐activatable fibrinolysis inhibitor (TAFI) is a circulating zymogen that is activated physiologically by the thrombin/thrombomodulin complex to…”
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Enhanced wound healing by topical application of ointment containing a low concentration of povidone-iodine by Mitani, O, Nishikawa, A, Kurokawa, I, Gabazza, E.C, Ikeda, M, Mizutani, H

“…Objective: To investigate the effect of a novel topical wound-healing agent, low-concentration povidone-iodine ointment (LPIO) with a hydrophobic white…”
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Thrombin-activatable fibrinolysis inhibitor (TAFI) is enhanced in major trauma patients without infectious complications by Relja, B, Lustenberger, T, Puttkammer, B, Jakob, H, Morser, J, Gabazza, E.C, Takei, Y, Marzi, I

“…Abstract Background Infectious complications frequently occur after major trauma, leading to increased morbidity and mortality. Thrombin-activatable…”
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Procaterol Suppresses Epithelial to Mesenchymal Transition (EMT) of Bronchial Epithelial Cells Induced By Eosinophils by Kainuma, Keigo, MD, Fujisawa, Takao, MD, FAAAAI, Hosoki, Koa, MD, PhD, Toda, Masaaki, Harada, Etsuko, Chelakkot-Govindalayathila, A.L, D'Alessandro-Gabazza, C.N, Gabazza, E.C

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Activated Thrombin-Activatable Fibrinolysis Inhibitor (TAFIa) Levels are decreased in Patients With Trauma-Induced Coagulopathy by Lustenberger, T, Relja, B, Puttkammer, B, Gabazza, E.C, Geiger, E, Takei, Y, Morser, J, Marzi, I

“…Abstract Introduction The thrombin-activatable fibrinolysis inhibitor (TAFI) is a potent inhibitor of fibrinolysis. However, the time course of TAFI and its…”
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A prospective comparison of nursing home-acquired pneumonia with hospital-acquired pneumonia in non-intubated elderly by Maruyama, T, Niederman, M.S, Kobayashi, T, Kobayashi, H, Takagi, T, D'Alessandro-Gabazza, C.N, Fujimoto, H, Gil Bernabe, P, Hirohata, S, Nakayama, S, Nishikubo, K, Yuda, H, Yamaguchi, A, Gabazza, E.C, Noguchi, T, Takei, Y, Taguchi, O

“…Summary There are no prospective comparison of the etiology and clinical outcome between hospital-acquired pneumonia (HAP) and nursing home-acquired pneumonia…”
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Eosinophils Promote Epithelial To Mesenchymal Transition Of Bronchial Epithelial Cells by Hosoki, K, Yasukawa, A, Toda, M, Miyake, Y, Ruiz, D.B, Bernabe, P.G, Takagi, T, Morooka, R, Nagao, M, DAlessandro-Gabazza, C.N, Taguchi, O, Gabazza, E.C, Fujisawa, T

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IL-4/IL-13 antagonist DNA vaccination successfully suppresses Th2 type chronic dermatitis by Morioka, T., Yamanaka, K., Mori, H., Omoto, Y., Tokime, K., Kakeda, M., Kurokawa, I., Gabazza, E.C., Tsubura, A., Yasutomi, Y., Mizutani, H.

“…Summary Background  Atopic dermatitis (AD) is a chronic disease with a Th2‐type‐cytokine dominant profile. Several cytokines and related peptides have been…”
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Circulating fibrocytes correlate with the asthma control test score by Kobayashi, H, Naito, M, Masuya, M, Maruyama, M, Urata, K, Takahashi, Y, Tomaru, A, Fujiwara, K, Ohnishi, M, Takagi, T, Kobayashi, T, D'Alessandro-Gabazza, C, Urawa, M, Gabazza, E C, Taguchi, O, Takei, Y

“…Bronchial asthma is characterised by airway inflammation and remodelling with a decline of lung function. Fibrocytes are bone marrow-derived mesenchymal…”
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Protein C inhibitor directly and potently inhibits activated hepatocyte growth factor activator by HAYASHI, T., NISHIOKA, J., NAKAGAWA, N., KAMADA, H., GABAZZA, E. C., KOBAYASHI, T., HATTORI, A., SUZUKI, K.

“…Summary Background: Hepatocyte growth factor (HGF) plays an important role in tissue repair and regeneration. HGF activator (HGFA), a factor XIIa‐like serine…”
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High incidence of tumors in diabetic thrombin activatable fibrinolysis inhibitor and apolipoprotein E double‐deficient mice by BEPPU, T., GIL‐BERNABE, P., BOVEDA‐RUIZ, D., D'ALESSANDRO‐GABAZZA, C., MATSUDA, Y., TODA, M., MIYAKE, Y., SHIRAKI, K., MURATA, M., MURATA, T., YANO, Y., MORSER, J., GABAZZA, E. C., TAKEI, Y.

“…Background: Activation of the complement system has been implicated in tumor growth. The antifibrinolytic protein, activated thrombin‐activatable fibrinolysis…”
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Pulmonary hypertension is ameliorated in mice deficient in thrombin‐activatable fibrinolysis inhibitor by QIN, L., D’ALESSANDRO‐GABAZZA, C. N., AOKI, S., GIL‐BERNABE, P., YANO, Y., TAKAGI, T., BOVEDA‐RUIZ, D., RAMIREZ MARMOL, A. Y., SAN MARTIN MONTENEGRO, V. T., TODA, M., MIYAKE, Y., TAGUCHI, O., TAKEI, Y., MORSER, J., GABAZZA, E. C.

“…Background: The fibrinolytic system has been implicated in the pathogenesis of pulmonary hypertension (PH). Thrombin‐activatable fibrinolysis inhibitor (TAFI)…”
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Protective Effect of Thrombomodulin in a Murine Model of Allergen-Induced Asthma by Takagi, T, Onishi, M, Urawa, M, Naito, M, Fujiwara, A, Kobayashi, T, Kobayashi, H, Toda, M, Boveda, D, Gil-Bernabe, P, D'Alessandro-Gabazza, C.N, Morser, J, Taguchi, O, Gabazza, E.C

“…Thrombomodulin (TM), the thrombin receptor on the endothelial cell surface, plays an important role in coagulation and inflammation by inactivating thrombin…”
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Protective role of thrombin activatable fibrinolysis inhibitor in obstructive nephropathy‐associated tubulointerstitial fibrosis by BRUNO, N. E., YANO, Y., TAKEI, Y., GABAZZA, E. C., QIN, L., NAGASHIMA, M., MORSER, J., D'ALESSANDRO‐GABAZZA, C. N., TAGUCHI, O., SUMIDA, Y.

“…Background: Thrombin‐activatable fibrinolysis inhibitor (TAFI) has been reported to affect wound healing and fibrotic processes, but its role in renal…”
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Characterization of a novel human protein C inhibitor (PCI) gene transgenic mouse useful for studying the role of PCI in physiological and pathological conditions by Hayashi, T., Nishioka, J., Kamada, H., Asanuma, K., Kondo, H., Gabazza, E. C., Ido, M., Suzuki, K.

“…In humans, protein C inhibitor (PCI) is expressed in various tissues and present in many body fluids including plasma and seminal fluid. In rodents, PCI is…”
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Protective role of protein C inhibitor in monocrotaline‐induced pulmonary hypertension by NISHII, Y., GABAZZA, E.C., FUJIMOTO, H., NAKAHARA, H., TAKAGI, T., BRUNO, N., D'ALESSANDRO‐GABAZZA, C. N., MARUYAMA, J., MARUYAMA, K., HAYASHI, T., ADACHI, Y., SUZUKI, K., TAGUCHI, O.

“…Background: Protein C inhibitor (PCI) plays a role in multiple biological processes including fertilization, coagulation, fibrinolysis and kinin systems…”
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Activation of protein C pathway in the airways by Hataji, O, Taguchi, O, Gabazza, E C, Yuda, H, Fujimoto, H, Suzuki, K, Adachi, Y

“…The protein C (PC) pathway plays important roles in the regulation of the coagulation system and inflammatory response. This study evaluated the degree of PC…”
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1535P Efficacy and safety of amrubicin after treatment with immune checkpoint inhibitor combined with chemotherapy in extensive-stage small cell carcinoma: MiSSION1 by Nishimura, T., Fujimoto, H., Fujiwara, T., Ito, K., Fujiwara, A., Yuda, H., Itani, H., D'Alessandro-Gabazza, C.N., Gabazza, E.C., Kobayashi, T.

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Protein S is protective in pulmonary fibrosis by Urawa, M., Kobayashi, T., D'Alessandro‐Gabazza, C. N., Fujimoto, H., Toda, M., Roeen, Z., Hinneh, J. A., Yasuma, T., Takei, Y., Taguchi, O., Gabazza, E. C.

“…Essentials Epithelial cell apoptosis is critical in the pathogenesis of idiopathic pulmonary fibrosis. Protein S, a circulating anticoagulant, inhibited…”
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Protein S exacerbates alcoholic hepatitis by stimulating liver natural killer T cells by Chelakkot‐Govindalayathil, A.‐L., Mifuji‐Moroka, R., D'Alessandro‐Gabazza, C. N., Toda, M., Matsuda, Y., Gil‐Bernabe, P., Roeen, Z., Yasuma, T., Yano, Y., Gabazza, E. C., Iwasa, M., Takei, Y.

“…Summary Background Alcohol consumption is a major cause of liver injury but the mechanisms are not completely understood. Protein S (PS) is an anticoagulant…”
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