Search Results - "Gaaied, El"
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Polymorphisms in VDR gene in Tunisian postmenopausal women are associated with osteopenia phenotype
Published in Climacteric : the journal of the International Menopause Society (01-08-2015)“…Abstract Objectives Osteopenia is characterized by intermediate values of bone mineral density (BMD) as compared to normal and osteoporotic subjects. BMD, a…”
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The investigation of the origin of Southern Tunisians using HLA genes
Published in Journal of human genetics (01-03-2017)“…The south of Tunisia is characterized by marked ethnic diversity, highlighted by the coexistence of native Berbers with Blacks, Jews and Arab-speaking…”
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Genetic variation of 17 X-chromosome STR loci in Tunisian population of Nabeul
Published in International journal of legal medicine (01-01-2019)“…In the present study, the genetic variations of 17 X-STR markers (DXS8378, DXS9898, DXS7133, GATA31E08, GATA172D05, DXS6801, DXS7423, DXS6809, DXS6799,…”
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HLA Class I and Class II Alleles and Haplotypes Confirm the Berber Origin of the Present Day Tunisian Population
Published in PloS one (28-08-2015)“…In view of its distinct geographical location and relatively small area, Tunisia witnessed the presence of many civilizations and ethnic groups throughout…”
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Gut microbiota, an emergent target to shape the efficiency of cancer therapy
Published in Exploration of targeted anti-tumor therapy (2023)“…It is now well-acknowledged that microbiota has a profound influence on both human health and illness. The gut microbiota has recently come to light as a…”
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CARD14 alterations in Tunisian patients with psoriasis and further characterization in European cohorts
Published in British journal of dermatology (1951) (01-02-2016)“…Summary Background Rare highly penetrant gain‐of‐function mutations in caspase recruitment domain family, member 14 (CARD14) can lead to psoriasis, a chronic…”
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New Insight into the human genetic diversity in North African populations by genotyping of SNPs in DRD3, CSMD1 and NRG1 genes
Published in Molecular genetics & genomic medicine (01-03-2022)“…Background The single nucleotide polymorphisms (SNPs) of the dopamine D3 receptor (DRD3), the CUB and sushi multiple domains 1 (CSMD1) and the neuregulin 1…”
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BRCA1/BRCA2 Mutations Shaped by Ancient Consanguinity Practice in Southern Mediterranean Populations
Published in Asian Pacific journal of cancer prevention : APJCP (26-10-2018)“…The aim of this study is to investigate the involvement of consanguinity on BRCA1/2 mutation incidence in Southern Mediterranean populations and to confirm…”
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Internal diversification of mitochondrial haplogroup R0a reveals post-last glacial maximum demographic expansions in South Arabia
Published in Molecular biology and evolution (01-01-2011)“…Widespread interest in the first successful Out of Africa dispersal of modern humans ∼60-80 thousand years ago via a southern migration route has overshadowed…”
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643C > T RANKL gene polymorphism is associated with osteoporosis in Tunisian postmenopausal women
Published in Climacteric : the journal of the International Menopause Society (01-08-2017)“…Objectives: The dynamic nature of the skeleton is achieved by a remodeling process. Receptor activator of nuclear factor kappa B (RANK) ligand (RANKL)…”
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Clinical significance of T-bet, GATA-3, and Bcl-6 transcription factor expression in bladder carcinoma
Published in Journal of translational medicine (30-05-2016)“…The aim of this study was to investigate the clinical significance of three immune cell-related transcription factors, T-bet, GATA-3 and Bcl-6 in bladder…”
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Akt activation correlates with the tumor aggressiveness in Tunisian patients with bladder cancer
Published in Tumor biology (01-06-2016)“…Various studies in western countries found Akt amplification to be a frequent event in human cancers, including bladder, but the correlation with…”
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A meta-analysis of the relationship between FGFR3 and TP53 mutations in bladder cancer
Published in PloS one (13-12-2012)“…TP53 and FGFR3 mutations are the most common mutations in bladder cancers. FGFR3 mutations are most frequent in low-grade low-stage tumours, whereas TP53…”
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Mitochondrial DNA analysis of Tunisians reveals a mosaic genetic structure with recent population expansion
Published in Homo : internationale Zeitschrift fur die vergleichende Forschung am Menschen (01-08-2017)“…Tunisia is a country of great interest for human population genetics due to its strategic geographic position and rich human settlement history. These factors…”
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Mitochondrial DNA Heterogeneity in Tunisian Berbers
Published in Annals of human genetics (01-05-2004)“…Summary Berbers live in groups scattered across North Africa whose origins and genetic relationships with their neighbours are not well established. The first…”
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PRNP polymorphisms in Tunisian sheep breeds
Published in Livestock science (01-09-2014)“…In this study, genetic variation of ovine prion protein in Tunisian sheep breeds was analysed. Sequencing of the entire coding sequence of prion protein gene…”
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Assessment of Aurora A kinase expression in breast cancer: a tool for early diagnosis?
Published in Disease markers (2013)“…Aurora A kinase is overexpressed in many cancers but the status of this protein in the breast cancer often varies. We investigate the expression and…”
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Obesity and renal cancer: Role of adipokines in the tumor-immune system conflict
Published in Oncoimmunology (01-01-2014)“…Epidemiological studies link obesity, as measured by increased body mass index (BMI) to the incidence of renal cell carcinoma (RCC) as well as to the…”
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Data from complete mtDNA sequencing of Tunisian centenarians: Testing haplogroup association and the “golden mean” to longevity
Published in Mechanisms of ageing and development (01-04-2009)“…Since the mitochondrial theory of ageing was proposed, mitochondrial DNA (mtDNA) diversity has been largely studied in old people, however complete genomes are…”
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Association analysis of LCE3C–LCE3B deletion in Tunisian psoriatic population
Published in Archives of Dermatological Research (01-11-2012)“…An association between a common deletion comprising the late cornified envelope LCE3B and LCE3C genes (LCE3C_LCE3B-del) and psoriasis has been reported in…”
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