Search Results - "GUTIERREZ, Marcelo M"

The Next Generation Scientist program: capacity-building for future scientific leaders in low- and middle-income countries by Pillai, Goonaseelan, Chibale, Kelly, Constable, Edwin C, Keller, Akiko N, Gutierrez, Marcelo M, Mirza, Fareed, Sengstag, Christian, Masimirembwa, Collen, Denti, Paolo, Maartens, Gary, Ramsay, Michèle, Ogutu, Bernhards, Makonnen, Eyasu, Gordon, Richard, Ferreira, Carlos Gil, Goldbaum, Fernando Alberto, Degrave, Wim M S, Spector, Jonathan, Tadmor, Brigitta, Kaiser, Hedwig J

“…Scientific and professional development opportunities for early career scientists in low- and middle- income countries (LMICs) are limited and not consistent…”
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Comparative Pharmacokinetic, Pharmacodynamic, Safety, and Tolerability Profiles of 3 Different Formulations of Epoprostenol Sodium for Injection in Healthy Men by Nicolas, Laurent B., PhD, Gutierrez, Marcelo M., PhD, Dingemanse, Jasper, PharmD, PhD

“…Abstract Background Epoprostenol sodium for injection is approved for the treatment of severe cases of primary pulmonary arterial hypertension. Currently,…”
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Prevalence of rheumatic heart disease in Zambian school children by Musuku, John, Engel, Mark E, Musonda, Patrick, Lungu, Joyce Chipili, Machila, Elizabeth, Schwaninger, Sherri, Mtaja, Agnes, Mulendele, Evans, Kavindele, Dorothy, Spector, Jonathan, Tadmor, Brigitta, Gutierrez, Marcelo M, Van Dam, Joris, Colin, Laurence, Long, Aidan, Fishman, Mark C, Mayosi, Bongani M, Zühlke, Liesl J

“…The large global burden of rheumatic heart disease (RHD) has come to light in recent years following robust epidemiologic studies. As an operational research…”
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An evaluation of the potential for pharmacokinetic interaction between escitalopram and the cytochrome P450 3A4 inhibitor ritonavir by Gutierrez, Marcelo M., Rosenberg, Jeffrey, Abramowitz, Wattanaporn

“…Background: Depression often coexists with a number of disease states, and patients with a diagnosis of depression often receive multiple medications. Thus, it…”
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A Randomized, Placebo-Controlled Trial of Citalopram for the Treatment of Major Depression in Children and Adolescents by Wagner, Karen Dineen, Robb, Adelaide S., Findling, Robert L., Jin, Jianqing, Gutierrez, Marcelo M., Heydorn, William E.

“…OBJECTIVE: Open-label trials with the selective serotonin reuptake inhibitor citalopram suggest that this agent is effective and safe for the treatment of…”
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Integrated pharmacokinetics and pharmacodynamics of epoprostenol in healthy subjects by Nicolas, Laurent B., Krause, Andreas, Gutierrez, Marcelo M., Dingemanse, Jasper

“…WHAT IS ALREADY KNOWN • Continuous infusion with synthetic prostacyclin (epoprostenol) is generally regarded as the most effective treatment against severe…”
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Relative bioavailability of a newly developed pediatric formulation of bosentan vs. the adult formulation by GUTIERREZ, Marcelo M, NICOLAS, Laurent B, DONAZZOLO, Yves, DINGEMANSE, Jasper

“…Bosentan is a dual endothelin receptor antagonist approved for the treatment of pulmonary arterial hypertension (PAH). Since bosentan is frequently used to…”
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Entry-into-humans study with a new direct renin inhibitor by Nicolas, Laurent B., Gutierrez, Marcelo M., Binkert, Christoph, Dingemanse, Jasper

“…Purpose To evaluate the pharmacokinetics, pharmacodynamics, safety, and tolerability of escalating single oral doses of ACT-077825, a novel orally active renin…”
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Tolerability and Pharmacokinetics of ACT-280778, a Novel Nondihydropyridine Dual L/T-type Calcium Channel Blocker: Early Clinical Studies in Healthy Male Subjects Using Adaptive Designs by Mueller, Markus S, Shakeri-Nejad, Kasra, Gutierrez, Marcelo M, Krause, Andreas, Täubel, Jörg, Sanderson, Brian, Dingemanse, Jasper

“…ACT-280778 is a novel nondihydropyridine dual L/T-type calcium channel blocker. Two clinical studies (AC-067-101 and AC-067-102) were conducted to characterize…”
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Pharmacokinetic comparison of oral solution and tablet formulations of citalopram: a single-dose, randomized, crossover study by Gutierrez, Marcelo M., Abramowitz, Wattanaporn

“…Background: Citalopram tablets fulfill most dosing needs in the treatment of depression, but some patients may have difficulty swallowing tablets and thus may…”
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Further characterization of the sodium-dependent nucleoside transporter (N3) in choroid plexus from rabbit by Wu, X, Gutierrez, M M, Giacomini, K M

“…The Na+/nucleoside cotransporter in rabbit choroid plexus differs from Na+/nucleoside cotransporters in other tissues in terms of substrate selectivity and…”
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Substrate selectivity, potential sensitivity and stoichiometry of Na(+)-nucleoside transport in brush border membrane vesicles from human kidney by Gutierrez, M M, Giacomini, K M

“…Recently, we demonstrated the presence of a Na(+)-nucleoside cotransport mechanism that transports both purine and pyrimidine nucleosides in human renal…”
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Interaction of nucleoside analogues with the sodium-nucleoside transport system in brush border membrane vesicles from human kidney by BRETT, C. M, WASHINGTON, C. B, OTT, R. J, GUTIERREZ, M. M, GIACOMINI, K. M

“…The therapeutic efficacy of nucleosides and nucleoside analogues as antitumor, antiviral, antiparasitic, and antiarrhythmic agents has been well documented…”
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Nucleoside transport in brush border membrane vesicles from human kidney by Gutierrez, M M, Brett, C M, Ott, R J, Hui, A C, Giacomini, K M

“…The goal of this study was to elucidate the mechanisms of nucleoside transport in the brush border membrane of the human kidney. [3H]Uridine was transported…”
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Isolated renal brush border and basolateral membrane vesicles and cultured renal cells by Gutierrez, M M, Brett, C M, Giacomini, K M

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