Search Results - "GUPTA, Samir K"

Tenofovir-associated Fanconi syndrome: review of the FDA adverse event reporting system by Gupta, Samir K

“…Tenofovir disoproxil fumarate (TDF) is a commonly used HIV antiretroviral. A relatively uncommon adverse effect of this drug is Fanconi syndrome. What is known…”
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HIV infection, antiretroviral therapy, and measures of endothelial function, inflammation, metabolism, and oxidative stress by Dysangco, Andrew, Liu, Ziyue, Stein, James H, Dubé, Michael P, Gupta, Samir K

“…HIV-infected patients have an increased risk of cardiovascular disease (CVD). Impaired endothelial function is an early risk factor for CVD in the general…”
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MASLD in persons with HIV is associated with high cardiometabolic risk as evidenced by altered advanced lipoprotein profiles and targeted metabolomics by Lin, Kung-Hung, Vilar-Gomez, Eduardo, Corey, Kathleen E, Connelly, Margery A, Gupta, Samir K, Lake, Jordan E, Chalasani, Naga, Gawrieh, Samer

“…Metabolic dysfunction associated steatotic liver disease (MASLD) is associated with increased cardiovascular disease (CVD) risk in persons with HIV (PWH). The…”
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Non-alcoholic fatty liver disease is not associated with impairment in health-related quality of life in virally suppressed persons with human immune deficiency virus by Gawrieh, Samer, Corey, Kathleen E, Lake, Jordan E, Samala, Niharika, Desai, Archita P, Debroy, Paula, Sjoquist, Julia A, Robison, Montreca, Tann, Mark, Akisik, Fatih, Bhamidipalli, Surya S, Saha, Chandan K, Zachary, Kimon, Robbins, Gregory K, Gupta, Samir K, Chung, Raymond T, Chalasani, Naga

“…Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in persons with HIV (PWH) (HIV-NAFLD). It is unknown if HIV-NAFLD is associated with…”
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Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction by Wang, Ting, Green, Linden A, Gupta, Samir K, Kim, Chul, Wang, Liang, Almodovar, Sharilyn, Flores, Sonia C, Prudovsky, Igor A, Jolicoeur, Paul, Liu, Ziyue, Clauss, Matthias

“…With effective antiretroviral therapy (ART), cardiovascular diseases (CVD) are emerging as a major cause of morbidity and death in the aging HIV-infected…”
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Immune reconstitution in ART treated, but not untreated HIV infection, is associated with abnormal beta cell function by Sims, Emily K, Park, Grace, Mather, Kieren J, Mirmira, Raghavendra G, Liu, Ziyue, Gupta, Samir K

“…HIV infection has been associated with increased diabetes risk, but prior work has mostly focused on insulin resistance, as opposed to beta cell effects, or…”
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Guidelines for the Management of Chronic Kidney Disease in HIV-Infected Patients: Recommendations of the HIV Medicine Association of the Infectious Diseases Society of America by Gupta, Samir K., Eustace, Joseph A., Winston, Jonathan A., Boydstun, Ivy I., Ahuja, Tejinder S., Rodriguez, Rudolph A., Tashima, Karen T., Roland, Michelle, Franceschini, Nora, Palella, Frank J., Lennox, Jeffrey L., Klotman, Paul E., Nachman, Sharon A., Hall, Stephen D., Szczech, Lynda A.

“…Several lines of evidence point to kidney disease as an important complication of human immunodeficiency virus infection. here, Gupta et al present some…”
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Insomnia symptoms and biomarkers of monocyte activation, systemic inflammation, and coagulation in HIV: Veterans Aging Cohort Study by Polanka, Brittanny M, Kundu, Suman, So-Armah, Kaku A, Freiberg, Matthew S, Gupta, Samir K, Zapolski, Tamika C B, Hirsh, Adam T, Bedimo, Roger J, Budoff, Matthew J, Butt, Adeel A, Chang, Chung-Chou H, Gottlieb, Stephen S, Marconi, Vincent C, Womack, Julie A, Stewart, Jesse C

“…Insomnia may be a risk factor for cardiovascular disease in HIV (HIV-CVD); however, mechanisms have yet to be elucidated. We examined cross-sectional…”
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A pilot study to determine the impact on dyslipidemia of adding tenofovir to stable background antiretroviral therapy: ACTG 5206 by TUNGSIRIPAT, Marisa, KITCH, Douglas, GLESBUY, Marshall J, GUPTA, Samir K, MELLORS, John W, MORAN, Laura, JONES, Lynne, ALSTON-SMITH, Beverly, ROONEY, James F, ABERG, Judith A

“…Several studies have reported improvement in lipids after antiretroviral therapy switches to tenofovir disoproxil fumarate (TDF)-containing regimens. We…”
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Fanconi syndrome accompanied by renal function decline with tenofovir disoproxil fumarate: a prospective, case-control study of predictors and resolution in HIV-infected patients by Gupta, Samir K, Anderson, Albert M, Ebrahimi, Ramin, Fralich, Todd, Graham, Hiba, Scharen-Guivel, Valeska, Flaherty, John F, Fortin, Claude, Kalayjian, Robert C, Rachlis, Anita, Wyatt, Christina M

“…The predictors of Fanconi syndrome (FS) accompanied by renal function decline with use of the antiretroviral tenofovir disoproxil fumarate (TDF) have not been…”
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Depression as a Risk Factor for Incident Ischemic Stroke Among HIV-Positive Veterans in the Veterans Aging Cohort Study by Sico, Jason J, Kundu, Suman, So-Armah, Kaku, Gupta, Samir K, Chang, Chung-Chou H, Butt, Adeel A, Gibert, Cynthia L, Marconi, Vincent C, Crystal, Stephen, Tindle, Hilary A, Freiberg, Matthew S, Stewart, Jesse C

“…Background HIV infection and depression are each associated with increased ischemic stroke risk. Whether depression is a risk factor for stroke within the HIV…”
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Worsening endothelial function with efavirenz compared to protease inhibitors: a 12-month prospective study by Gupta, Samir K, Shen, Changyu, Moe, Sharon M, Kamendulis, Lisa M, Goldman, Mitchell, Dubé, Michael P

“…Changes in endothelial function, measured as flow-mediated dilation (FMD) of the brachial artery, has not been systematically assessed beyond 6 months of…”
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Relationship between microbial translocation and endothelial function in HIV infected patients by Blodget, Emily, Shen, Changyu, Aldrovandi, Grace, Rollie, Adrienne, Gupta, Samir K, Stein, James H, Dubé, Michael P

“…Circulating levels of microbial products are increased in HIV infection, and provoke endothelial dysfunction in other disease settings. We examined data from a…”
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Pharmacokinetics, safety, and tolerability of ribavirin in hemodialysis-dependent patients by Gupta, Samir K., Kantesaria, Bhavna, Glue, Paul

“…Purpose This study describes the pharmacokinetics, safety, and tolerability of ribavirin in hemodialysis-dependent patients. Methods Six adult patients…”
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Beetroot supplementation in women enjoying exercise together (BEE SWEET): Rationale, design and methods by Baranauskas, Marissa N., Altherr, Cody A., Gruber, Allison H., Coggan, Andrew R., Raglin, John S., Gupta, Samir K., Carter, Stephen J.

“…Postmenopausal women exhibit higher rates of disability and cardiovascular disease (CVD) with aging compared to men. Whereas habitual exercise training is a…”
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Pentoxifylline, inflammation, and endothelial function in HIV-infected persons: a randomized, placebo-controlled trial by Gupta, Samir K, Mi, Deming, Dubé, Michael P, Saha, Chandan K, Johnson, Raymond M, Stein, James H, Clauss, Matthias A, Mather, Kieren J, Desta, Zeruesenay, Liu, Ziyue

“…Untreated HIV may increase the risk of cardiovascular events. Our preliminary in vitro and in vivo research suggests that pentoxifylline (PTX) reduces vascular…”
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Hemoptysis: Beyond routine chest computed tomography and bronchoscopy by Mall, Saurabh, Sharma, Rahul Kumar, Prajapat, Deepak, Gupta, Samir K, Talwar, Deepak

“…Hemoptysis is considered as a medical emergency which requires urgent stabilization with identification and correction of underlying etiology. Diagnosis of the…”
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A 58-Year-old Man With Multifocal Pulmonary Nodules by McClean, Mitchell, Gupta, Samir K, Relich, Ryan F

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Exploring the influence of renal dysfunction on the pharmacokinetics of ribavirin after oral and intravenous dosing by K Gupta, Samir, Kantesaria, Bhavna, Glue, Paul

“…Although ribavirin is minimally cleared by renal elimination, its pharmacokinetics are substantially altered in patients with chronic renal impairment. This…”
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Immune checkpoints and pancreatic beta cell dysfunction in HIV by Pryke, Luke A, Liu, Ziyue, Khaitan, Alka K, Sims, Emily K, Gupta, Samir K

“…We explored the impact of immune dysregulation on pancreatic beta cell injury in HIV patients. Analyzing 105 participant samples, we observed lower IL-21…”
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