Search Results - "GUOBIN TIAN"
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Global dissemination of H5N1 influenza viruses bearing the clade 2.3.4.4b HA gene and biologic analysis of the ones detected in China
Published in Emerging microbes & infections (31-12-2022)“…H5N1 avian influenza viruses bearing the clade 2.3.4.4b hemagglutinin gene have been widely circulating in wild birds and are responsible for the loss of over…”
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Highly Pathogenic Avian Influenza Virus (H5N1) Clade 2.3.4.4b Introduced by Wild Birds, China, 2021
Published in Emerging infectious diseases (01-07-2023)“…Highly pathogenic avian influenza (HPAI) subtype H5N1 clade 2.3.4.4b virus has spread globally, causing unprecedented large-scale avian influenza outbreaks…”
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H5N1 Hybrid Viruses Bearing 2009/H1N1 Virus Genes Transmit in Guinea Pigs by Respiratory Droplet
Published in Science (American Association for the Advancement of Science) (21-06-2013)“…In the past, avian influenza viruses have crossed species barriers to trigger human pandemics by reassorting with mammal-infective viruses in intermediate…”
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Genetic and biological properties of H7N9 avian influenza viruses detected after application of the H7N9 poultry vaccine in China
Published in PLoS pathogens (01-04-2021)“…The H7N9 avian influenza virus (AIV) that emerged in China have caused five waves of human infection. Further human cases have been successfully prevented…”
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Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses
Published in PLoS pathogens (01-11-2014)“…H9N2 subtype influenza viruses have been detected in different species of wild birds and domestic poultry in many countries for several decades. Because these…”
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Novel H5N6 reassortants bearing the clade 2.3.4.4b HA gene of H5N8 virus have been detected in poultry and caused multiple human infections in China
Published in Emerging microbes & infections (01-12-2022)“…The globally circulating H5N8 avian influenza viruses bearing the clade 2.3.4.4b hemagglutinin (HA) gene are responsible for the loss of more than 33 million…”
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A Single-Amino-Acid Substitution in the NS1 Protein Changes the Pathogenicity of H5N1 Avian Influenza Viruses in Mice
Published in Journal of Virology (01-02-2008)“…Erratum ( vol. 82 , p. 4190 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious…”
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H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet
Published in Science (American Association for the Advancement of Science) (26-07-2013)“…A newly emerged H7N9 virus has caused 132 human infections with 37 deaths in China since 18 February 2013. Control measures in H7N9 virus—positive live poultry…”
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Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host
Published in PLoS pathogens (01-12-2009)“…Since 2003, H5N1 influenza viruses have caused over 400 known cases of human infection with a mortality rate greater than 60%. Most of these cases resulted…”
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PIAS1-mediated SUMOylation of influenza A virus PB2 restricts viral replication and virulence
Published in PLoS pathogens (04-04-2022)“…Host defense systems employ posttranslational modifications to protect against invading pathogens. Here, we found that protein inhibitor of activated STAT 1…”
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The G Protein-Coupled Receptor FFAR2 Promotes Internalization during Influenza A Virus Entry
Published in Journal of virology (06-01-2020)“…Influenza A virus (IAV) coopts numerous host factors to complete its replication cycle. Here, we identify free fatty acid receptor 2 (FFAR2) as a cofactor for…”
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Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China
Published in Science China. Life sciences (01-04-2022)“…The H5N8 avian influenza viruses have been widely circulating in wild birds and are responsible for the loss of over 33 million domestic poultry in Europe,…”
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Complex Reassortment of Multiple Subtypes of Avian Influenza Viruses in Domestic Ducks at the Dongting Lake Region of China
Published in Journal of Virology (01-09-2013)“…OA Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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Continued Evolution of H5N1 Influenza Viruses in Wild Birds, Domestic Poultry, and Humans in China from 2004 to 2009
Published in Journal of Virology (01-09-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Expression and characterization of recombinant antibodies against H7 subtype avian influenza virus and their diagnostic potential
Published in Frontiers in microbiology (2024)“…Monoclonal antibodies (mAbs) play a pivotal role in disease diagnosis as well as immunotherapy interventions. Traditional monoclonal antibody generation relies…”
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The NS1 Gene Contributes to the Virulence of H5N1 Avian Influenza Viruses
Published in Journal of Virology (01-11-2006)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Low Polymerase Activity Attributed to PA Drives the Acquisition of the PB2 E627K Mutation of H7N9 Avian Influenza Virus in Mammals
Published in mBio (18-06-2019)“…Avian influenza viruses (AIVs) must acquire mammalian-adaptive mutations before they can efficiently replicate in and transmit among humans. The PB2 E627K…”
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Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission
Published in PLoS pathogens (01-02-2021)“…Posttranslational modifications, such as SUMOylation, play specific roles in the life cycle of invading pathogens. However, the effect of SUMOylation on the…”
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On-Site and Visual Detection of the H5 Subtype Avian Influenza Virus Based on RT-RPA and CRISPR/Cas12a
Published in Viruses (10-05-2024)“…Avian influenza viruses (AIVs) of the H5 subtype rank among the most serious pathogens, leading to significant economic losses in the global poultry industry…”
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Two amino acid residues in the matrix protein M1 contribute to the virulence difference of H5N1 avian influenza viruses in mice
Published in Virology (New York, N.Y.) (05-02-2009)“…Abstract A/duck/Guangxi/53/2002 (DKGX/53) and A/duck/Fujian/01/2002 (DKFJ/01) are H5N1 avian influenza viruses that are lethal in chickens. In mice, however,…”
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