Search Results - "GUO, Yuan"

SpatialDWLS: accurate deconvolution of spatial transcriptomic data by Dong, Rui, Yuan, Guo-Cheng

“…Recent development of spatial transcriptomic technologies has made it possible to characterize cellular heterogeneity with spatial information. However, the…”
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Neutrinophilic axion-like dark matter by Huang, Guo-yuan, Nath, Newton

“…The axion-like particles (ALPs) are very good candidates of the cosmological dark matter, which can exist in many extensions of the standard model (SM). The…”
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The biphasic function of microglia in ischemic stroke by Ma, Yuanyuan, Wang, Jixian, Wang, Yongting, Yang, Guo-Yuan

“…Microglia are brain resident macrophages originated from primitive progenitor cells in the yolk sac. Microglia can be activated within hours and recruited to…”
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GiniClust: detecting rare cell types from single-cell gene expression data with Gini index by Jiang, Lan, Chen, Huidong, Pinello, Luca, Yuan, Guo-Cheng

“…High-throughput single-cell technologies have great potential to discover new cell types; however, it remains challenging to detect rare cell types that are…”
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Double and multiple bangs at tau neutrino telescopes by Huang, Guo-yuan

“…In light of the exciting campaign of cosmogenic neutrino detection, we investigate the double and multiple tau bangs detectable at future tau neutrino…”
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Giotto: a toolbox for integrative analysis and visualization of spatial expression data by Dries, Ruben, Zhu, Qian, Dong, Rui, Eng, Chee-Huat Linus, Li, Huipeng, Liu, Kan, Fu, Yuntian, Zhao, Tianxiao, Sarkar, Arpan, Bao, Feng, George, Rani E, Pierson, Nico, Cai, Long, Yuan, Guo-Cheng

“…Spatial transcriptomic and proteomic technologies have provided new opportunities to investigate cells in their native microenvironment. Here we present…”
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GiniClust2: a cluster-aware, weighted ensemble clustering method for cell-type detection by Tsoucas, Daphne, Yuan, Guo-Cheng

“…Single-cell analysis is a powerful tool for dissecting the cellular composition within a tissue or organ. However, it remains difficult to detect rare and…”
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Accurate estimation of cell-type composition from gene expression data by Tsoucas, Daphne, Dong, Rui, Chen, Haide, Zhu, Qian, Guo, Guoji, Yuan, Guo-Cheng

“…The rapid development of single-cell transcriptomic technologies has helped uncover the cellular heterogeneity within cell populations. However, bulk RNA-seq…”
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Tentative sensitivity of future 0νββ-decay experiments to neutrino masses and Majorana CP phases by Huang, Guo-yuan, Zhou, Shun

“…A bstract In the near future, the neutrinoless double-beta (0 νββ ) decay experiments will hopefully reach the sensitivity of a few meV to the effective…”
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Identification of spatially associated subpopulations by combining scRNAseq and sequential fluorescence in situ hybridization data by Zhu, Qian, Shah, Sheel, Dries, Ruben, Cai, Long, Yuan, Guo-Cheng

“…Combining single-cell RNA-seq with sequential single-molecule FISH defines the influence of spatial location on cell identity. How intrinsic gene-regulatory…”
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GiniClust3: a fast and memory-efficient tool for rare cell type identification by Dong, Rui, Yuan, Guo-Cheng

“…With the rapid development of single-cell RNA sequencing technology, it is possible to dissect cell-type composition at high resolution. A number of methods…”
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Ductile 2-GPa steels with hierarchical substructure by Li, Yunjie, Yuan, Guo, Li, Linlin, Kang, Jian, Yan, Fengkai, Du, Pengju, Raabe, Dierk, Wang, Guodong

“…Mechanically strong and ductile load-carrying materials are needed in all sectors, from transportation to lightweight design to safe infrastructure. Yet, a…”
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Photoredox/Hydrogen Atom Transfer Cocatalyzed C–H Difluoroallylation of Amides, Ethers, and Alkyl Aldehydes by Guo, Yuan-Qiang, Wu, Yifan, Wang, Ruiguo, Song, Hongjian, Liu, Yuxiu, Wang, Qingmin

“…Herein, we report a method that combines hydrogen atom transfer and photoredox catalysis to achieve the dehydrogenative difluoroallylation of amides, ethers,…”
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GSCA: an integrated platform for gene set cancer analysis at genomic, pharmacogenomic and immunogenomic levels by Liu, Chun-Jie, Hu, Fei-Fei, Xie, Gui-Yan, Miao, Ya-Ru, Li, Xin-Wen, Zeng, Yan, Guo, An-Yuan

“…Abstract Cancer initiation and progression are likely caused by the dysregulation of biological pathways. Gene set analysis (GSA) could improve the…”
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GSDS 2.0: an upgraded gene feature visualization server by Hu, Bo, Jin, Jinpu, Guo, An-Yuan, Zhang, He, Luo, Jingchu, Gao, Ge

“…: Visualizing genes' structure and annotated features helps biologists to investigate their function and evolution intuitively. The Gene Structure Display…”
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lncRNASNP2: an updated database of functional SNPs and mutations in human and mouse lncRNAs by Miao, Ya-Ru, Liu, Wei, Zhang, Qiong, Guo, An-Yuan

“…Abstract Long non-coding RNAs (lncRNAs) are emerging as important regulators in different biological processes through various ways. Because the related data,…”
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Sestrin2 regulates microglia polarization through mTOR-mediated autophagic flux to attenuate inflammation during experimental brain ischemia by He, Tingting, Li, Wanlu, Song, Yaying, Li, Zongwei, Tang, Yaohui, Zhang, Zhijun, Yang, Guo-Yuan

“…Abstract Background Neuroinflammation is the major pathogenesis of cerebral ischemia. Microglia are activated and polarized to either the pro-inflammatory M1…”
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Stroke subtype-dependent synapse elimination by reactive gliosis in mice by Shi, Xiaojing, Luo, Longlong, Wang, Jixian, Shen, Hui, Li, Yongfang, Mamtilahun, Muyassar, Liu, Chang, Shi, Rubing, Lee, Joon-Hyuk, Tian, Hengli, Zhang, Zhijun, Wang, Yongting, Chung, Won-Suk, Tang, Yaohui, Yang, Guo-Yuan

“…The pathological role of reactive gliosis in CNS repair remains controversial. In this study, using murine ischemic and hemorrhagic stroke models, we…”
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Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion by Zhang, Lin-Yuan, Pan, Jiaji, Mamtilahun, Muyassar, Zhu, Yuan, Wang, Liping, Venkatesh, Ashwin, Shi, Rubing, Tu, Xuanqiang, Jin, Kunlin, Wang, Yongting, Zhang, Zhijun, Yang, Guo-Yuan

“…Microglial activation participates in white matter injury after cerebral hypoperfusion. However, the underlying mechanism is unclear. Here, we explore whether…”
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Assimilating the global satellite mapping of precipitation data with the Nonhydrostatic Icosahedral Atmospheric Model (NICAM) by Kotsuki, Shunji, Miyoshi, Takemasa, Terasaki, Koji, Lien, Guo‐Yuan, Kalnay, Eugenia

“…This study aims to propose two new approaches to improve precipitation forecasts from numerical weather prediction (NWP) models through effective data…”
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