Search Results - "GUO, Jiancheng"
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1
Liposomes for Tumor Targeted Therapy: A Review
Published in International journal of molecular sciences (31-01-2023)“…Liposomes, the most widely studied nano-drug carriers in drug delivery, are sphere-shaped vesicles consisting of one or more phospholipid bilayers. Compared…”
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2
Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma
Published in Nature communications (22-07-2020)“…Epigenetic landscapes can shape physiologic and disease phenotypes. We used integrative, high resolution multi-omics methods to delineate the methylome…”
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3
Overview of chicken embryo genes related to sex differentiation
Published in PeerJ (San Francisco, CA) (19-03-2024)“…Sex determination in chickens at an early embryonic stage has been a longstanding challenge in poultry production due to the unique ZZ:ZW sex chromosome system…”
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4
Dynamics of binding ability prediction between spike protein and human ACE2 reveals the adaptive strategy of SARS-CoV-2 in humans
Published in Scientific reports (04-02-2021)“…SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel coronavirus causing the COVID-19 pandemic in 2020. High adaptive plasticity on the…”
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5
Genetic testing in pediatric kidney transplant recipients to promote informed choice and improve individualized monitoring
Published in Orphanet journal of rare diseases (03-10-2024)“…The growing body of research on kidney disease in children has identified a broad spectrum of genetic etiologies. We conducted a prospective study to evaluate…”
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6
Research on the influence of thermal expansion of steel shaft on dynamic characteristics of full ceramic bearing-rotor system
Published in Advances in mechanical engineering (01-07-2022)“…Bearing as the core components of high-grade CNC machine tools, with the constant change of internal clearance of bearing wear increasingly aggravated, spindle…”
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7
Application of Metal-Based Nanozymes in Inflammatory Disease: A Review
Published in Frontiers in bioengineering and biotechnology (16-06-2022)“…Reactive oxygen species (ROS) are metabolites of normal cells in organisms, and normal levels of ROS in cells are essential for maintaining cell signaling and…”
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Novel compound heterozygous pathogenic variants in the SLC3A1 gene in a Chinese family with cystinuria
Published in BMC medical genomics (19-12-2023)“…Cystinuria is an autosomal recessive disorder characterized by a cystine transport deficiency in the renal tubules due to mutations in two genes: SLC3A1 and…”
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9
Frontiers in the COVID-19 vaccines development
Published in Experimental hematology & oncology (03-09-2020)“…Abstract Novel corona virus caused pneumonia first reported in December, 2019 in Wuhan, China was later named COVID-19. Due to its special pathogenicity,…”
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10
Involvement of Glutathione Depletion in Selective Cytotoxicity of Oridonin to p53-Mutant Esophageal Squamous Carcinoma Cells
Published in Frontiers in oncology (15-01-2020)“…Oridonin, a diterpenoid compound isolated from traditional Chinese medicine Rabdosia rubescens, has shown antitumor effects to esophageal cancer. However, its…”
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11
OShnscc: a novel user-friendly online survival analysis tool for head and neck squamous cell carcinoma based on RNA expression profiles and long-term survival information
Published in Journal of Zhejiang University. B. Science (15-03-2022)“…Head and neck squamous cell carcinoma (HNSCC), as the most common type (>90%) of head and neck cancer, includes various epithelial malignancies that arise in…”
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12
A Recurrent PDGFRB Mutation Causes Familial Infantile Myofibromatosis
Published in American journal of human genetics (06-06-2013)“…Infantile myofibromatosis (IM) is the most common benign fibrous tumor of soft tissues affecting young children. By using whole-exome sequencing, RNA…”
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13
Rock Granularity Analysis by Deep Belief Network
Published in MATEC Web of Conferences (01-01-2017)“…Granularity analysis is one of the most essential issues in authenticate. To improve the identification accuracy, a Deep Belief Network (DBN) based method is…”
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14
Thymosin alpha-1 blocks the accumulation of myeloid suppressor cells in NSCLC by inhibiting VEGF production
Published in Biomedicine & pharmacotherapy (01-11-2020)“…[Display omitted] •Thymosin alpha-1 promotes the apoptosis and inhibits the migration of M-MDSCs.•Thymosin alpha-1 inhibits NSCLC tumor growth.•Inhibition of…”
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15
Prevalence and reclassification of BRCA1 and BRCA2 variants in a large, unselected Chinese Han breast cancer cohort
Published in Journal of hematology and oncology (18-01-2021)“…Accurate interpretation of BRCA1/2 variants is critical for risk assessment and precise treatment of breast cancer (BC). Hence, the establishment of an…”
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16
pH‐Activatable Pre‐Nanozyme Mediated H2S Delivery for Endo‐Exogenous Regulation of Oxidative Stress in Acute Kidney Injury
Published in Advanced science (01-05-2024)“…Oxidative stress induced by excess reactive oxygen species (ROS) is a primary pathogenic cause of acute kidney injury (AKI). Development of an effective…”
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17
Lighting up Individual Organelles With Fluorescent Carbon Dots
Published in Frontiers in chemistry (26-11-2021)“…Cell organelles play crucial roles in the normal functioning of an organism, therefore the disruption of their operation is associated with diseases and in…”
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Camptothecin Delivery via Tumor-Derived Exosome for Radiosensitization by Cell Cycle Regulation on Patient-Derived Xenograft Mice
Published in Frontiers in bioengineering and biotechnology (12-04-2022)“…While radiotherapy remains the leading clinical treatment for many tumors, its efficacy can be significantly hampered by the insensitivity of cells in the S…”
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19
Transcriptomic Analysis Reveals the Effects of miR-122 Overexpression in the Liver of Qingyuan Partridge Chickens
Published in Animals (Basel) (22-07-2024)“…The liver of chickens is essential for maintaining physiological activities and homeostasis. This study aims to investigate the specific function and molecular…”
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Genetic Epidemiology of Medication Safety and Efficacy Related Variants in the Central Han Chinese Population With Whole Genome Sequencing
Published in Frontiers in pharmacology (23-02-2022)“…Medication safety and efficacy-related pharmacogenomic research play a critical role in precision medicine. This study comprehensively analyzed the…”
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