Search Results - "GUNTER, Jeffrey L"

Cascading network failure across the Alzheimer's disease spectrum by Jones, David T, Knopman, David S, Gunter, Jeffrey L, Graff-Radford, Jonathan, Vemuri, Prashanthi, Boeve, Bradley F, Petersen, Ronald C, Weiner, Michael W, Jack, Jr, Clifford R

“…Complex biological systems are organized across various spatiotemporal scales with particular scientific disciplines dedicated to the study of each scale (e.g…”
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Defining imaging biomarker cut points for brain aging and Alzheimer's disease by Jack, Clifford R, Wiste, Heather J, Weigand, Stephen D, Therneau, Terry M, Lowe, Val J, Knopman, David S, Gunter, Jeffrey L, Senjem, Matthew L, Jones, David T, Kantarci, Kejal, Machulda, Mary M, Mielke, Michelle M, Roberts, Rosebud O, Vemuri, Prashanthi, Reyes, Denise A, Petersen, Ronald C

“…Abstract Introduction Our goal was to develop cut points for amyloid positron emission tomography (PET), tau PET, flouro-deoxyglucose (FDG) PET, and MRI…”
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Non-stationarity in the "resting brain's" modular architecture by Jones, David T, Vemuri, Prashanthi, Murphy, Matthew C, Gunter, Jeffrey L, Senjem, Matthew L, Machulda, Mary M, Przybelski, Scott A, Gregg, Brian E, Kantarci, Kejal, Knopman, David S, Boeve, Bradley F, Petersen, Ronald C, Jack, Jr, Clifford R

“…Task-free functional magnetic resonance imaging (TF-fMRI) has great potential for advancing the understanding and treatment of neurologic illness. However, as…”
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Age-specific and sex-specific prevalence of cerebral β-amyloidosis, tauopathy, and neurodegeneration in cognitively unimpaired individuals aged 50–95 years: a cross-sectional study by Jack, Clifford R, Prof, Wiste, Heather J, BA, Weigand, Stephen D, MS, Therneau, Terry M, Prof, Knopman, David S, Prof, Lowe, Val, Prof, Vemuri, Prashanthi, PhD, Mielke, Michelle M, Prof, Roberts, Rosebud O, Prof, Machulda, Mary M, PhD, Senjem, Matthew L, MS, Gunter, Jeffrey L, PhD, Rocca, Walter A, Prof, Petersen, Ronald C, Prof

“…Summary Background A new classification for biomarkers in Alzheimer's disease and cognitive ageing research is based on grouping the markers into three…”
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An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease by Jack Jr, Clifford R., Knopman, David S., Weigand, Stephen D., Wiste, Heather J., Vemuri, Prashanthi, Lowe, Val, Kantarci, Kejal, Gunter, Jeffrey L., Senjem, Matthew L., Ivnik, Robert J., Roberts, Rosebud O., Rocca, Walter A., Boeve, Bradley F., Petersen, Ronald C.

“…Objective: A workgroup commissioned by the Alzheimer's Association (AA) and the National Institute on Aging (NIA) recently published research criteria for…”
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Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50–89 years: a cross-sectional study by Jack, Clifford R, Prof, Wiste, Heather J, BA, Weigand, Stephen D, MS, Rocca, Walter A, Prof, Knopman, David S, Prof, Mielke, Michelle M, PhD, Lowe, Val J, Prof, Senjem, Matthew L, MS, Gunter, Jeffrey L, PhD, Preboske, Gregory M, MS, Pankratz, Vernon S, PhD, Vemuri, Prashanthi, PhD, Petersen, Ronald C, Prof

“…Summary Background As preclinical Alzheimer's disease becomes a target for therapeutic intervention, the overlap between imaging abnormalities associated with…”
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Predicting future rates of tau accumulation on PET by Jack, Clifford R, Wiste, Heather J, Weigand, Stephen D, Therneau, Terry M, Lowe, Val J, Knopman, David S, Botha, Hugo, Graff-Radford, Jonathan, Jones, David T, Ferman, Tanis J, Boeve, Bradley F, Kantarci, Kejal, Vemuri, Prashanthi, Mielke, Michelle M, Whitwell, Jennifer, Josephs, Keith, Schwarz, Christopher G, Senjem, Matthew L, Gunter, Jeffrey L, Petersen, Ronald C

“…Clinical trials with anti-tau drugs will need to target individuals at risk of accumulating tau. Our objective was to identify variables available in a…”
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Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly by Vemuri, Prashanthi, Lesnick, Timothy G, Przybelski, Scott A, Knopman, David S, Preboske, Greg M, Kantarci, Kejal, Raman, Mekala R, Machulda, Mary M, Mielke, Michelle M, Lowe, Val J, Senjem, Matthew L, Gunter, Jeffrey L, Rocca, Walter A, Roberts, Rosebud O, Petersen, Ronald C, Jack, Jr, Clifford R

“…Our primary objective was to investigate a biomarker driven model for the interrelationships between vascular disease pathology, amyloid pathology, and…”
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Associations of quantitative susceptibility mapping with Alzheimer's disease clinical and imaging markers by Cogswell, Petrice M., Wiste, Heather J., Senjem, Matthew L., Gunter, Jeffrey L., Weigand, Stephen D., Schwarz, Christopher G., Arani, Arvin, Therneau, Terry M., Lowe, Val J., Knopman, David S., Botha, Hugo, Graff-Radford, Jonathan, Jones, David T., Kantarci, Kejal, Vemuri, Prashanthi, Boeve, Bradley F, Mielke, Michelle M., Petersen, Ronald C., Jack, Clifford R.

“…Altered iron metabolism has been hypothesized to be associated with Alzheimer's disease pathology, and prior work has shown associations between iron load and…”
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Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease by Jack, Clifford R., Lowe, Val J., Weigand, Stephen D., Wiste, Heather J., Senjem, Matthew L., Knopman, David S., Shiung, Maria M., Gunter, Jeffrey L., Boeve, Bradley F., Kemp, Bradley J., Weiner, Michael, Petersen, Ronald C.

“…The purpose of this study was to use serial imaging to gain insight into the sequence of pathologic events in Alzheimer's disease, and the clinical features…”
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A standard system phantom for magnetic resonance imaging by Stupic, Karl F., Ainslie, Maureen, Boss, Michael A., Charles, Cecil, Dienstfrey, Andrew M., Evelhoch, Jeffrey L., Finn, Paul, Gimbutas, Zydrunas, Gunter, Jeffrey L., Hill, Derek L. G., Jack, Clifford R., Jackson, Edward F., Karaulanov, Todor, Keenan, Kathryn E., Liu, Guoying, Martin, Michele N., Prasad, Pottumarthi V., Rentz, Nikki S., Yuan, Chun, Russek, Stephen E.

“…Purpose A standard MRI system phantom has been designed and fabricated to assess scanner performance, stability, comparability and assess the accuracy of…”
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Changing the face of neuroimaging research: Comparing a new MRI de-facing technique with popular alternatives by Schwarz, Christopher G., Kremers, Walter K., Wiste, Heather J., Gunter, Jeffrey L., Vemuri, Prashanthi, Spychalla, Anthony J., Kantarci, Kejal, Schultz, Aaron P., Sperling, Reisa A., Knopman, David S., Petersen, Ronald C., Jack, Clifford R.

“…Recent advances in automated face recognition algorithms have increased the risk that de-identified research MRI scans may be re-identifiable by matching them…”
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Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study by Jack, Clifford R, Prof, Therneau, Terry M, Prof, Wiste, Heather J, BA, Weigand, Stephen D, MS, Knopman, David S, Prof, Lowe, Val J, Prof, Mielke, Michelle M, PhD, Vemuri, Prashanthi, PhD, Roberts, Rosebud O, Prof, Machulda, Mary M, PhD, Senjem, Matthew L, MS, Gunter, Jeffrey L, PhD, Rocca, Walter A, Prof, Petersen, Ronald C, Prof

“…Summary Background In a 2014 cross-sectional analysis, we showed that amyloid and neurodegeneration biomarker states in participants with no clinical…”
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White Matter Integrity on DTI and the Pathologic Staging of Alzheimer’s Disease by Kantarci, Kejal, MD, MS, Murray, Melissa E., PhD, Schwarz, Christopher G., PhD, Reid, Robert, PhD, Przybelski, Scott A, Lesnick, Timothy, MS, Zuk, Samantha M, Raman, Mekala R., PhD, Senjem, Matthew L., MS, Gunter, Jeffrey L., PhD, Boeve, Bradley F., MD, Knopman, David S., MD, Parisi, Joseph E., MD, Petersen, Ronald C., MD, PhD, Jack, Clifford R., MD, Dickson, Dennis, MD

“…Abstract Pattern of diffusion tensor MRI (DTI) alterations were investigated in pathologically-staged Alzheimer’s disease (AD) patients (n=46). Patients with…”
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Quantitative magnetic resonance imaging phantoms: A review and the need for a system phantom by Keenan, Kathryn E., Ainslie, Maureen, Barker, Alex J., Boss, Michael A., Cecil, Kim M., Charles, Cecil, Chenevert, Thomas L., Clarke, Larry, Evelhoch, Jeffrey L., Finn, Paul, Gembris, Daniel, Gunter, Jeffrey L., Hill, Derek L.G., Jack, Clifford R., Jackson, Edward F., Liu, Guoying, Russek, Stephen E., Sharma, Samir D., Steckner, Michael, Stupic, Karl F., Trzasko, Joshua D., Yuan, Chun, Zheng, Jie

“…The MRI community is using quantitative mapping techniques to complement qualitative imaging. For quantitative imaging to reach its full potential, it is…”
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A large-scale comparison of cortical thickness and volume methods for measuring Alzheimer's disease severity by Schwarz, Christopher G, Gunter, Jeffrey L, Wiste, Heather J, Przybelski, Scott A, Weigand, Stephen D, Ward, Chadwick P, Senjem, Matthew L, Vemuri, Prashanthi, Murray, Melissa E, Dickson, Dennis W, Parisi, Joseph E, Kantarci, Kejal, Weiner, Michael W, Petersen, Ronald C, Jack, Jr, Clifford R

“…Alzheimer's disease (AD) researchers commonly use MRI as a quantitative measure of disease severity. Historically, hippocampal volume has been favored…”
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The evolution of primary progressive apraxia of speech by JOSEPHS, Keith A, DUFFY, Joseph R, JACK, Clifford R, WHITWELL, Jennifer L, STRAND, Edythe A, MACHULDA, Mary M, SENJEM, Matthew L, GUNTER, Jeffrey L, SCHWARZ, Christopher G, REID, Robert I, SPYCHALLA, Anthony J, LOWE, Val J

“…Primary progressive apraxia of speech is a recently described neurodegenerative disorder in which patients present with an isolated apraxia of speech and show…”
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Selecting software pipelines for change in flortaucipir SUVR: Balancing repeatability and group separation by Schwarz, Christopher G., Therneau, Terry M., Weigand, Stephen D., Gunter, Jeffrey L., Lowe, Val J., Przybelski, Scott A., Senjem, Matthew L., Botha, Hugo, Vemuri, Prashanthi, Kantarci, Kejal, Boeve, Bradley F., Whitwell, Jennifer L., Josephs, Keith A., Petersen, Ronald C., Knopman, David S., Jack, Clifford R.

“…Since tau PET tracers were introduced, investigators have quantified them using a wide variety of automated methods. As longitudinal cohort studies acquire…”
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Face recognition from research brain PET: An unexpected PET problem by Schwarz, Christopher G., Kremers, Walter K., Lowe, Val J., Savvides, Marios, Gunter, Jeffrey L., Senjem, Matthew L., Vemuri, Prashanthi, Kantarci, Kejal, Knopman, David S., Petersen, Ronald C., Jack, Clifford R.

“…It is well known that de-identified research brain images from MRI and CT can potentially be re-identified using face recognition; however, this has not been…”
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Effect of lifestyle activities on alzheimer disease biomarkers and cognition by Vemuri, Prashanthi, Lesnick, Timothy G., Przybelski, Scott A., Knopman, David S., Roberts, Rosebud O., Lowe, Val J., Kantarci, Kejal, Senjem, Mathew L., Gunter, Jeffrey L., Boeve, Bradley F., Petersen, Ronald C., Jack Jr, Clifford R.

“…Objective: A study was undertaken to investigate the association of intellectual and physical activity with biomarkers of Alzheimer disease (AD)…”
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