Search Results - "GUMUCIO, D"

Peroxisome proliferator activated receptor γ in colonic epithelial cells protects against experimental inflammatory bowel disease by Adachi, M, Kurotani, R, Morimura, K, Shah, Y, Sanford, M, Madison, B B, Gumucio, D L, Marin, H E, Peters, J M, Young, H A, Gonzalez, F J

“…Introduction: Peroxisome proliferator activated receptor γ (PPARγ) is expressed in epithelial cells, macrophage, and T and B lymphocytes. Ligand induced…”
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Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever by Aksentijevich, I, Centola, M, Deng, Zuoming, Sood, R, Balow, JE Jr, Wood, G, Zaks, N, Mansfield, E, Chen, Xiang, Eisenberg, S, Vedula, A, Shafran, N, Raben, N, Pras, E, Pras, M

“…Familial Mediterranean fever (FMF) is a recessively inherited disorder characterized by dramatic episodes of fever and serosal inflammation. This report…”
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Epithelial hedgehog signals pattern the intestinal crypt-villus axis by Madison, Blair B, Braunstein, Katherine, Kuizon, Erlene, Portman, Kathleen, Qiao, Xiaotan T, Gumucio, Deborah L

“…Morphological development of the small intestinal mucosa involves the stepwise remodeling of a smooth-surfaced endodermal tube to form finger-like luminal…”
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cis Elements of the Villin Gene Control Expression in Restricted Domains of the Vertical (Crypt) and Horizontal (Duodenum, Cecum) Axes of the Intestine by Madison, Blair B., Dunbar, Laura, Qiao, Xiaotan T., Braunstein, Katherine, Braunstein, Evan, Gumucio, Deborah L.

“…Villin, an actin bundling protein found in the apical brush border of absorptive tissues, is one of the first structural genes to be transcriptionally…”
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Interaction between Pyrin and the Apoptotic Speck Protein (ASC) Modulates ASC-induced Apoptosis by Richards, Neil, Schaner, Philip, Diaz, Arturo, Stuckey, Jeanne, Shelden, Eric, Wadhwa, Anish, Gumucio, Deborah L.

“…Patients with familial Mediterranean fever suffer sporadic inflammatory attacks characterized by fever and intense pain (in joints, abdomen, or chest). Pyrin,…”
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ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis by Masumoto, Junya, Dowds, Theresa A, Schaner, Philip, Chen, Felicia F, Ogura, Yasunori, Li, Mu, Zhu, Li, Katsuyama, Tsutomu, Sagara, Junji, Taniguchi, Shun'ichiro, Gumucio, Deborah L, Núñez, Gabriel, Inohara, Naohiro

“…ASC is a pro-apoptotic protein containing a pyrin domain (PD) and a caspase-recruitment domain (CARD). A previous study suggests that ASC interacts with Ipaf,…”
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Tissue stem cells and cancer stem cells: potential implications for gastric cancer by Gumucio, D L, Fagoonee, S, Qiao, X T, Liebert, M, Merchant, J L, Altruda, F, Rizzetto, M, Pellicano, R

“…Gastric cancer remains the second leading cause of death in the world today, making the search for its molecular and cellular basis an important priority…”
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Locus control regions of mammalian β-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights by Hardison, Ross, Slightom, Jerry L., Gumucio, Deborah L., Goodman, Morris, Stojanovic, Nikola, Miller, Webb

“…Locus control regions (LCRs) are cis-acting DNA segments needed for activation of an entire locus or gene cluster. They are operationally defined as DNA…”
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Fire and ICE: the role of pyrin domain-containing proteins in inflammation and apoptosis by Gumucio, D L, Diaz, A, Schaner, P, Richards, N, Babcock, C, Schaller, M, Cesena, T

“…The genetic bases for several human autoinflammatory syndromes have recently been identified, and the mutated proteins responsible for these diseases are…”
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Phylogenetic footprinting reveals a nuclear protein which binds to silencer sequences in the human gamma and epsilon globin genes by Gumucio, D L, Heilstedt-Williamson, H, Gray, T A, Tarlé, S A, Shelton, D A, Tagle, D A, Slightom, J L, Goodman, M, Collins, F S

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification of a stage selector element in the human gamma‐globin gene promoter that fosters preferential interaction with the 5′ HS2 enhancer when in competition with the beta‐promoter by Jane, S.M., Ney, P.A., Vanin, E.F., Gumucio, D.L., Nienhuis, A.W.

“…The erythroid‐specific enhancer within hypersensitivity site 2 (HS2) of the human beta‐globin locus control region is required for high level globin gene…”
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Severe Acute Kidney Injury in Patients with COVID-19 and Acute Respiratory Distress Syndrome by Chaibi, Khalil, Dao, Myriam, Pham, Tài, Gumucio-Sanguino, Victor D, Di Paolo, Fabio A, Pavot, Arthur, Cohen, Yves, Dreyfuss, Didier, Pérez-Fernandez, Xosé, Gaudry, Stéphane

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Isolation of intestinal epithelial cells for the study of differential gene expression along the crypt-villus axis by Traber, P G, Gumucio, D L, Wang, W

“…Methods for the differential isolation of intestinal epithelial cells from crypt and villus compartments of small intestine have been used in the study of…”
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Familial Mediterranean fever and hyperimmunoglobulinemia D syndrome: two diseases with distinct clinical, serologic, and genetic features by Livneh, A, Drenth, J P, Klasen, I S, Langevitz, P, George, J, Shelton, D A, Gumucio, D L, Pras, E, Kastner, D L, Pras, M, van der Meer, J W

“…To determine whether the 2 periodic febrile syndromes familial Mediterranean fever (FMF) and hyperimmunoglobulinemia D syndrome (HIDS) are distinct diseases…”
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Methylation-enhanced binding of Sp1 to the stage selector element of the human γ-globin gene promoter may regulate developmental specificity of expression by JANE, S. M, GUMUCIO, D. L, NEY, P. A, CUNNINGHAM, J. M, NIENHUIS, A. W

“…The human gamma -globin gene promoter contains a stage selector element (SSE) responsible for preferential interaction of the promoter with a powerful…”
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Nuclear proteins that bind the human gamma-globin gene promoter: alterations in binding produced by point mutations associated with hereditary persistence of fetal hemoglobin by GUMUCIO, D. L, ROOD, K. L, GRAY, T. A, RIORDAN, M. F, SARTOR, C. I, COLLINS, F. S

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Phylogenetic Footprinting Reveals Unexpected Complexity in Trans Factor Binding Upstream from the ε-Globin Gene by Gumucio, Deborah L., Shelton, David A., Bailey, Wendy J., Slightom, Jerry L., Goodman, Morris

“…The human ε-globin gene undergoes dramatic changes in transcriptional activity during development, but the molecular factors that control its high expression…”
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Helicobacter-induced Intestinal Metaplasia in the Stomach Correlates with Elk-1 and Serum Response Factor Induction of Villin by Rieder, Gabriele, Tessier, Arthur J., Qiao, Xiaotan T., Madison, Blair, Gumucio, Deborah L., Merchant, Juanita L.

“…Chronic Helicobacter pylori infection results in serious sequelae, including atrophy, intestinal metaplasia, and gastric cancer. Intestinal metaplasia in the…”
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Targeted disruption of the mouse villin gene does not impair the morphogenesis of microvilli by Pinson, Kathleen I., Dunbar, Laura, Samuelson, Linda, Gumucio, Deborah L.

“…The small intestine is functionally dependent on the presence of the brush border, a tightly packed array of microvilli that forms the amplified apical surface…”
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Phylogenetic footprinting of hypersensitive site 3 of the β-globin locus control region by SHELTON, D. A, STEGMAN, L, HARDISON, R, MILLER, W, BOCK, J. H, SLIGHTOM, J. L, GOODMAN, M, GUMUCIO, D. L

“…Hypersensitive site 3 (HS3) of the beta-like globin locus control region has been implicated as an important regulator of the beta-like globin genes, but the…”
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