Search Results - "GULOKSUZ, SINAN"

A critique of the “ultra‐high risk” and “transition” paradigm by van Os, Jim, Guloksuz, Sinan

“…The transdiagnostic expression of psychotic experiences in common mental disorder (anxiety/depression/substance use disorder) is associated with a poorer…”
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Antipsychotics result in more weight gain in antipsychotic naive patients than in patients after antipsychotic switch and weight gain is irrespective of psychiatric diagnosis: A meta-analysis by Bak, Maarten, Drukker, Marjan, Cortenraad, Shauna, Vandenberk, Emma, Guloksuz, Sinan

“…Antipsychotics are associated with bodyweight gain and metabolic disturbance. Previous meta-analyses were limited to mainly antipsychotic switch studies in…”
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En attendant Godot: Waiting for the Funeral of “Schizophrenia” and the Baby Shower of the Psychosis Spectrum by Guloksuz, Sinan, van Os, Jim

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The experience sampling method as an mHealth tool to support self‐monitoring, self‐insight, and personalized health care in clinical practice by Os, Jim, Verhagen, Simone, Marsman, Anne, Peeters, Frenk, Bak, Maarten, Marcelis, Machteld, Drukker, Marjan, Reininghaus, Ulrich, Jacobs, Nele, Lataster, Tineke, Simons, Claudia, Lousberg, Richel, Gülöksüz, Sinan, Leue, Carsten, Groot, Peter C., Viechtbauer, Wolfgang, Delespaul, Philippe

“…Background The experience sampling method (ESM) builds an intensive time series of experiences and contexts in the flow of daily life, typically consisting of…”
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Neural cell‐derived plasma exosome protein abnormalities implicate mitochondrial impairment in first episodes of psychosis by Goetzl, Edward J., Srihari, Vinod H., Guloksuz, Sinan, Ferrara, Maria, Tek, Cenk, Heninger, George R.

“…Neuroprotective and other functional proteins of mitochondria were quantified in extracts of plasma neural‐derived exosomes from ten first‐episode psychosis…”
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Reduced regulatory T cells with increased proinflammatory response in patients with schizophrenia by Sahbaz, Cigdem, Zibandey, Noushin, Kurtulmus, Ayse, Duran, Yazgul, Gokalp, Muazzez, Kırpınar, Ismet, Sahin, Fikrettin, Guloksuz, Sinan, Akkoc, Tunc

“…Aim To investigate whether circulating T cells including regulatory T cells (Treg) and derived cytokines contribute to the immune imbalance observed in…”
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Decreased mitochondrial electron transport proteins and increased complement mediators in plasma neural-derived exosomes of early psychosis by Goetzl, Edward J., Srihari, Vinod H., Guloksuz, Sinan, Ferrara, Maria, Tek, Cenk, Heninger, George R.

“…Potentially neurotoxic systems involved in traumatic and degenerative diseases of the brain were assessed in acute psychosis. Astrocyte-derived exosomes (ADEs)…”
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Editorial: Substance use and the psychosis spectrum by Kirli, Umut, Guloksuz, Sinan, Elbi, Hayriye

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Antipsychotic-induced weight gain in first-episode psychosis patients: a meta-analysis of differential effects of antipsychotic medications by Tek, Cenk, Kucukgoncu, Suat, Guloksuz, Sinan, Woods, Scott W., Srihari, Vinod H., Annamalai, Aniyizhai

“…Aim The first‐episode psychosis (FEP) represents a critical period to prevent cardiovascular and metabolic morbidity decades later. Antipsychotic (AP)‐induced…”
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Emotion regulation in response to daily negative and positive events in youth: The role of event intensity and psychopathology by Hiekkaranta, Anu P., Kirtley, Olivia J., Lafit, Ginette, Decoster, Jeroen, Derom, Catherine, de Hert, Marc, Gülöksüz, Sinan, Jacobs, Nele, Menne-Lothmann, Claudia, Rutten, Bart P.F., Thiery, Evert, van Os, Jim, van Winkel, Ruud, Wichers, Marieke, Myin-Germeys, Inez

“…Environmental and individual contextual factors profoundly influence how people regulate their emotions. The current article addresses the role of event…”
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The Ethics of Risk Prediction for Psychosis and Suicide Attempt in Youth Mental Health by Smith, William R., Appelbaum, Paul S., Lebowitz, Matthew S., Gülöksüz, Sinan, Calkins, Monica E., Kohler, Christian G., Gur, Raquel E., Barzilay, Ran

“…To identify potential clinical utility of polygenic risk scores (PRS) and exposomic risk scores (ERS) for psychosis and suicide attempt in youth and assess the…”
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First help-seeking attempt before and after psychosis onset: measures of delay and aversive pathways to care by Ferrara, Maria, Guloksuz, Sinan, Mathis, Walter S., Li, Fangyong, Lin, I-Hsin, Syed, Sumaiyah, Gallagher, Keith, Shah, Jai, Kline, Emily, Tek, Cenk, Keshavan, Matcheri, Srihari, Vinod H.

“…Purpose Delay in receiving effective treatment for psychosis adversely impacts outcomes. We investigated the timing of the first help-seeking attempt in…”
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Associations Between Childhood Area-Level Social Fragmentation, Maladaptation to School, and Social Functioning Among Healthy Youth and Those at Clinical High Risk for Psychosis by Ku, Benson S, Addington, Jean, Bearden, Carrie E, Cadenhead, Kristin S, Cannon, Tyrone D, Compton, Michael T, Cornblatt, Barbara A, Druss, Benjamin G, Gülöksüz, Sinan, Mathalon, Daniel H, Perkins, Diana O, Tsuang, Ming T, Walker, Elaine F, Woods, Scott W, Carrión, Ricardo E

“…Abstract Background and Hypothesis Although studies have identified social fragmentation as an important risk factor for schizophrenia and other psychotic…”
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Association of the kynurenine pathway metabolites with clinical, cognitive features and IL-1β levels in patients with schizophrenia spectrum disorder and their siblings by Noyan, Handan, Erdağ, Ece, Tüzün, Erdem, Yaylım, İlhan, Küçükhüseyin, Özlem, Hakan, Mehmet Tolgahan, Gülöksüz, Sinan, Rutten, Bart P.F., Saka, Meram Can, Atbaşoğlu, Cem, Alptekin, Köksal, van Os, Jim, Üçok, Alp

“…There is evidence suggesting that tryptophan (TRP)-kynurenine (KYN) pathway dysregulation is involved in the pathophysiology of schizophrenia and is regulated…”
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General psychopathology and its social correlates in the daily lives of youth by Achterhof, Robin, Kirtley, Olivia J., Schneider, Maude, Hagemann, Noëmi, Hermans, Karlijn S.F.M., Hiekkaranta, Anu P., Lecei, Aleksandra, Decoster, Jeroen, Derom, Catherine, De Hert, Marc, Gülöksüz, Sinan, Jacobs, Nele, Menne-Lothmann, Claudia, Rutten, Bart P.F., Thiery, Evert, van Os, Jim, van Winkel, Ruud, Wichers, Marieke, Myin-Germeys, Inez

“…Adolescence is a period of both great social change, and of vulnerability to psychiatric distress. However, little is known about the associations between…”
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Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings by Velthorst, Eva, Mollon, Josephine, Murray, Robin M., de Haan, Lieuwe, Germeys, Inez Myin, Glahn, David C., Arango, Celso, van der Ven, Els, Di Forti, Marta, Bernardo, Miguel, Guloksuz, Sinan, Delespaul, Philippe, Mezquida, Gisela, Amoretti, Silvia, Bobes, Julio, Saiz, Pilar A., García-Portilla, María Paz, Santos, José Luis, Jiménez-López, Estela, Sanjuan, Julio, Aguilar, Eduardo J., Arrojo, Manuel, Carracedo, Angel, López, Gonzalo, González-Peñas, Javier, Parellada, Mara, Atbaşoğlu, Cem, Saka, Meram Can, Üçok, Alp, Alptekin, Köksal, Akdede, Berna, Binbay, Tolga, Altınyazar, Vesile, Ulaş, Halis, Yalınçetin, Berna, Gümüş-Akay, Güvem, Beyaz, Burçin Cihan, Soygür, Haldun, Cankurtaran, Eylem Şahin, Kaymak, Semra Ulusoy, Maric, Nadja P., Mihaljevic, Marina M., Petrovic, Sanja Andric, Mirjanic, Tijana, Del-Ben, Cristina Marta, Ferraro, Laura, Gayer-Anderson, Charlotte, Jones, Peter B., Jongsma, Hannah E., Kirkbride, James B., La Cascia, Caterina, Lasalvia, Antonio, Tosato, Sarah, Llorca, Pierre-Michel, Menezes, Paulo Rossi, Morgan, Craig, Quattrone, Diego, Menchetti, Marco, Selten, Jean-Paul, Szöke, Andrei, Tarricone, Ilaria, Tortelli, Andrea, McGuire, Philip, Valmaggia, Lucia, Kempton, Matthew J., van der Gaag, Mark, Riecher-Rössler, Anita, Bressan, Rodrigo A., Barrantes-Vidal, Neus, Nelson, Barnaby, McGorry, Patrick, Pantelis, Chris, Krebs, Marie-Odile, Ruhrmann, Stephan, Sachs, Gabriele, Rutten, Bart P. F., van Os, Jim, Alizadeh, Behrooz Z., van Amelsvoort, Therese, Bartels-Velthuis, Agna A., Bruggeman, Richard, van Beveren, Nico J., Luykx, Jurjen J., Cahn, Wiepke, Simons, Claudia J. P., Kahn, Rene S., Schirmbeck, Frederike, van Winkel, Ruud, Reichenberg, Abraham

“…Important questions remain about the profile of cognitive impairment in psychotic disorders across adulthood and illness stages. The age-associated profile of…”
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Interrogating Associations Between Polygenic Liabilities and Electroconvulsive Therapy Effectiveness by Luykx, Jurjen J., Loef, Dore, Lin, Bochao, van Diermen, Linda, Nuninga, Jasper O., van Exel, Eric, Oudega, Mardien L., Rhebergen, Didi, Schouws, Sigfried N.T.M., van Eijndhoven, Philip, Verwijk, Esmée, Schrijvers, Didier, Birkenhager, Tom K., Ryan, Karen M., Arts, Baer, van Bronswijk, Suzanne C., Kenis, Gunter, Schurgers, Geert, Baune, Bernhard T., Arns, Martijn, van Dellen, Edwin E., Somers, Metten, Sommer, Iris E.C., Boks, Marco P., Gülöksüz, Sinan, McLoughlin, Declan M., Dols, Annemiek, Rutten, Bart P.F.

“…Electroconvulsive therapy (ECT) is the most effective treatment for severe major depressive episodes (MDEs). Nonetheless, firmly established associations…”
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Estimating Aggregate Environmental Risk Score in Psychiatry: The Exposome Score for Schizophrenia by Pries, Lotta-Katrin, Erzin, Gamze, Rutten, Bart P. F., van Os, Jim, Guloksuz, Sinan

“…To understand the role of environment in the pathoetiology of psychosis spectrum disorders, research has thus far mainly investigated the effects of single…”
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Adjusting for population stratification in polygenic risk score analyses: a guide for model specifications in the UK Biobank by Lin, Bochao Danae, Pries, Lotta-Katrin, van Os, Jim, Luykx, Jurjen J, Rutten, Bart P F, Guloksuz, Sinan

“…The current study was conducted to provide a general guidance for model specifications in polygenic risk score (PRS) analyses of the UK Biobank, such as…”
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Analysis of GWAS-Derived Schizophrenia Genes for Links to Ischemia-Hypoxia Response of the Brain by Schmidt-Kastner, Rainald, Guloksuz, Sinan, Kietzmann, Thomas, van Os, Jim, Rutten, Bart P. F.

“…Obstetric complications (OCs) can induce major adverse conditions for early brain development and predispose to mental disorders, including schizophrenia…”
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