Search Results - "GULERIA, Indira"

Glioproliferative Lesion of the Spinal Cord as a Complication of “Stem-Cell Tourism” by Berkowitz, Aaron L, Miller, Michael B, Mir, Saad A, Cagney, Daniel, Chavakula, Vamsidhar, Guleria, Indira, Aizer, Ayal, Ligon, Keith L, Chi, John H

“…A primitive neoplasm composed predominantly of nonhost cells was detected in the thoracic spinal cord and thecal sac of a 66-year-old man who had received…”
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Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses by Liu, Jun, Yuan, Ying, Chen, Wenna, Putra, Juan, Suriawinata, Arief A., Schenk, Austin D., Miller, Halli E., Guleria, Indira, Barth, Richard J., Huang, Yina H., Wang, Li

“…Significance Multiple immune-checkpoint proteins, such as programmed death 1 (PD-1), LAG3, and TIM3, are coexpressed on immune cells and functionally synergize…”
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Maternal Acceptance of the Fetus: True Human Tolerance by Guleria, Indira, Sayegh, Mohamed H

“…Induction and maintenance of immunologic tolerance in humans remains a desirable but elusive goal. Therefore, understanding the physiologic mechanisms of…”
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Clonal dynamics of alloreactive T cells in kidney allograft rejection after anti-PD-1 therapy by Dunlap, Garrett S., DiToro, Daniel, Henderson, Joel, Shah, Sujal I., Manos, Mike, Severgnini, Mariano, Weins, Astrid, Guleria, Indira, Ott, Patrick A., Murakami, Naoka, Rao, Deepak A.

“…Kidney transplant recipients are at particular risk for developing tumors, many of which are now routinely treated with immune checkpoint inhibitors (ICIs);…”
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Role of PD1/PDL1 pathway, and TH17 and treg cells in maternal tolerance to the fetus by Tripathi, Sudipta, Guleria, Indira

“…Tolerance of the fetus by the maternal immune system is regulated through various mechanisms involving the different immune cells, both in the periphery and…”
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Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3⁺CD4⁺ regulatory T cells by Wang, Li, Pino-Lagos, Karina, de Vries, Victor C, Guleria, Indira, Sayegh, Mohamed H, Noelle, Randolph J

“…Although mature dendritic cells (DCs) are potent initiators of adaptive immune response, immature steady-state DCs contribute to immune tolerance. In this…”
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The link between the PDL1 costimulatory pathway and Th17 in fetomaternal tolerance by D'Addio, Francesca, Riella, Leonardo V, Mfarrej, Bechara G, Chabtini, Lola, Adams, La Tonya, Yeung, Melissa, Yagita, Hideo, Azuma, Miyuki, Sayegh, Mohamed H, Guleria, Indira

“…Fetomaternal tolerance has been shown to depend both on regulatory T cells (Tregs) and negative signals from the PD1-PDL1 costimulatory pathway. More recently,…”
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TIM-3 regulates innate immune cells to induce fetomaternal tolerance by Chabtini, Lola, Mfarrej, Bechara, Mounayar, Marwan, Zhu, Bing, Batal, Ibrahim, Dakle, Pranal J, Smith, Brian D, Boenisch, Olaf, Najafian, Nader, Akiba, Hisaya, Yagita, Hideo, Guleria, Indira

“…TIM-3 is constitutively expressed on subsets of macrophages and dendritic cells. Its expression on other cells of the innate immune system and its role in…”
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Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway by Fife, Brian T, Guleria, Indira, Gubbels Bupp, Melanie, Eagar, Todd N, Tang, Qizhi, Bour-Jordan, Helene, Yagita, Hideo, Azuma, Miyuki, Sayegh, Mohamed H, Bluestone, Jeffrey A

“…The past decade has seen a significant increase in the number of potentially tolerogenic therapies for treatment of new-onset diabetes. However, most…”
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Distinct Non-Human Leukocyte Antigen Antibody Signatures Correlate with Endothelial Crossmatch Status in Lung and Renal Transplant Recipients by Alhamdan, Fahd, Coppolino, Antonio, Sheikh, Adil, Miele, Anna, Lee, Stefi, Gasiewski, Allison, Brescia, Peter, Wood, Isabelle, Venkat, Arvin, Thaniyavarn, Tany, Jacob, Selvin, Keshk, Mohamed, Meadowcroft, Stacia, Banday, Mudassir M, Khan, Mohd Moin, Hayes, Jr, Don, Chandrekar, Anil, Goldberg, Hilary, Guleria, Indira, Sharma, Nirmal S

“…Non-HLA antibodies against heterogeneous targets on endothelial cells have been associated with allograft injuries. The endothelial cell crossmatch (ECXM) is…”
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Biomarkers in Fetomaternal Tolerance by Tripathi, Sudipta, PhD, Guleria, Indira, PhD, D(ABHI)

“…Multiple mechanisms of tolerance operate in the immune cross-talk at the fetomaternal interface, contributing to successful pregnancy outcome. The cross-talk…”
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Ischemia augments alloimmune injury through IL-6-driven CD4+ alloreactivity by Uehara, Mayuko, Solhjou, Zhabiz, Banouni, Naima, Kasinath, Vivek, Xiaqun, Ye, Dai, Li, Yilmam, Osman, Yilmaz, Mine, Ichimura, Takaharu, Fiorina, Paolo, Martins, Paulo N., Ohori, Shunsuke, Guleria, Indira, Maarouf, Omar H., Tullius, Stefan G., McGrath, Martina M., Abdi, Reza

“…Ischemia reperfusion injuries (IRI) are unavoidable in solid organ transplantation. IRI augments alloimmunity but the mechanisms involved are poorly…”
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Multicenter phase I/II trial of the safety of allogeneic endothelial cell implants after the creation of arteriovenous access for hemodialysis use: The V-HEALTH study by Conte, Michael S., MD, Nugent, Helen M., PhD, Gaccione, Peter, MA, Guleria, Indira, MD, Roy-Chaudhury, Prabir, MD, PhD, Lawson, Jeffrey H., MD, PhD

“…Objectives Vascular access dysfunction is the major cause of morbidity in patients on hemodialysis to treat end stage renal disease. Preclinical studies have…”
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A critical role for the programmed death ligand 1 in fetomaternal tolerance by Guleria, Indira, Khosroshahi, Arezou, Ansari, Mohammed Javeed, Habicht, Antje, Azuma, Miyuki, Yagita, Hideo, Noelle, Randolph J, Coyle, Anthony, Mellor, Andrew L, Khoury, Samia J, Sayegh, Mohamed H

“…Fetal survival during gestation implies that tolerance mechanisms suppress the maternal immune response to paternally inherited alloantigens. Here we show that…”
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Blockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes by Kochupurakkal, Nora M, Kruger, Annie J, Tripathi, Sudipta, Zhu, Bing, Adams, La Tonya, Rainbow, Daniel B, Rossini, Aldo, Greiner, Dale L, Sayegh, Mohamed H, Wicker, Linda S, Guleria, Indira

“…Inhibition of PD1-PDL1 signaling in NOD mice accelerates onset of type 1 diabetes implicating this pathway in suppressing the emergence of pancreatic beta cell…”
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Effect of TIM-3 Blockade on the Immunophenotype and Cytokine Profile of Murine Uterine NK Cells by Tripathi, Sudipta, Chabtini, Lola, Dakle, Pranal J, Smith, Brian, Akiba, Hisaya, Yagita, Hideo, Guleria, Indira

“…NK cells are the most abundant lymphocyte population in the feto-maternal interface during gestation. The uterine NK cells (uNK) are transient, have a unique…”
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Targeting CD22 Reprograms B-Cells and Reverses Autoimmune Diabetes by FIORINA, Paolo, VERGANI, Andrea, RODIG, Scott, DUNUSSI-JOANNOPOULOS, Kyri, BLUESTONE, Jeffrey, SAYEGH, Mohamed H, DADA, Shirine, JUREWICZ, Mollie, WONG, Masie, LAW, Kenneth, ERXI WU, ZE TIAN, ABDI, Reza, GULERIA, Indira

“…Targeting CD22 Reprograms B-Cells and Reverses Autoimmune Diabetes Paolo Fiorina 1 2 , Andrea Vergani 1 2 , Shirine Dada 1 , Mollie Jurewicz 1 , Masie Wong 1 ,…”
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Association of Donor and Recipient Telomere Length with Clinical Outcomes following Lung Transplantation by Courtwright, Andrew M, Fried, Sabrina, Villalba, Julian A, Moniodis, Anna, Guleria, Indira, Wood, Isabelle, Milford, Edgar, Mallidi, Hari H, Hunninghake, Gary M, Raby, Benjamin A, Agarwal, Suneet, Camp, Philip C, Rosas, Ivan O, Goldberg, Hilary J, El-Chemaly, Souheil

“…Patients with short telomere syndromes and pulmonary fibrosis have increased complications after lung transplant. However, the more general impact of donor and…”
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Immune modulation by Lacto-N-fucopentaose III in experimental autoimmune encephalomyelitis by Zhu, Bing, Trikudanathan, Subbulaxmi, Zozulya, Alla L, Sandoval-Garcia, Carolina, Kennedy, Jennifer K, Atochina, Olga, Norberg, Thomas, Castagner, Bastien, Seeberger, Peter, Fabry, Zsuzsa, Harn, Donald, Khoury, Samia J, Guleria, Indira

“…Abstract Parasitic infections frequently lead to immune deviation or suppression. However, the application of specific parasitic molecules in regulating…”
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Critical Role of Donor Tissue Expression of Programmed Death Ligand-1 in Regulating Cardiac Allograft Rejection and Vasculopathy by JUN YANG, POPOOLA, Joyce, SHIN, Tahiro, YAGITA, Hideo, AZUMA, Miyuki, SAYEGH, Mohamed H, CHANDRAKER, Anil, KHANDWALA, Shakila, VADIVEL, Nidyanandh, VANGURI, Vijay, XUELI YUAN, DADA, Shirine, GULERIA, Indira, TIAN, Chaorui, JAVEED ANSARI, M

“…Allograft vasculopathy is a major limiting factor in the long-term success of cardiac transplantation. T cells play a critical role in initiation of cardiac…”
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